Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pamela Albaugh"'
Autor:
John F. Tallman, Geoff White, Matt Crago, Lu Marshall, James V. Cassella, Pamela Albaugh, James Gregory, Dorothy W. Gallagher, Hutchison Alan J, Phil C. Ross
Publikováno v:
Journal of medicinal chemistry. 45(23)
Benzodiazepines are allosteric modulators of the GABA(A) receptor. The traditionally prescribed benzodiazepines are nonselective and suffer from numerous side effects. Upon the identification of receptor subtypes, we set out to discover selective age
Publikováno v:
Tetrahedron Letters. 23:723-726
Ethyl 3-methyl-2-trimethylsilyl-3-butenoate ( 3 ) undergoes reaction selectively at carbon 4, upon treatment with a Lewis acid and carbonyl compounds, acetals/ketals, acid chlorides, and chloromethyl phenyl sulfide. This overall conversion represents
Publikováno v:
The Journal of Organic Chemistry. 48:5288-5302
Preparation d'un certain nombre d'esters du type methyl-3 trimethylsilyl-2 butene-3oate d'ethyle et etude de leurs reactions avec divers electrophiles (aldehydes, cetones, acetals, chlorures d'acyle etc.) en presence d'acides de Lewis (TiCl 4 et trif
Publikováno v:
Tetrahedron. 41:5861-5869
Treatment of the readily prepared enzymes 12, 21 and 45 with Co2(CO) at ca 110° results in high yields (80%) of substituted bicyclo[3.3.0]octenones, that are suitable for straightforward elaboration into coriolin and hirsutic acid precursors. A mech
Publikováno v:
J. Chem. Soc., Chem. Commun.. :804-806
Intramolecular cyclization of the methoxyallene–alkoxide adducts (1a) proceeds along two different pathways via a methoxyallyl radical to give either a dihydrofuran, or vinyl epoxide, depending upon the steric environment of the redical anion.
Publikováno v:
Chemischer Informationsdienst. 15
Intramolecular cyclization of the methoxyallene–alkoxide adducts (1a) proceeds along two different pathways via a methoxyallyl radical to give either a dihydrofuran, or vinyl epoxide, depending upon the steric environment of the redical anion.
Publikováno v:
Journal of the American Chemical Society. 101:5435-5436