Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Pamela A. Althof"'
Publikováno v:
Genes, Chromosomes and Cancer. 59:569-574
Multiple myeloma is a clonal malignancy of plasma cells in the bone marrow. Risk stratification is partly based on cytogenetic findings that include abnormalities of the IGH locus as determined by fluorescence in situ hybridization (FISH), such as re
Autor:
Cheng Wang, Pamela A. Althof, Guohua Yu, Weiwei Zhang, Jennifer N. Sanmann, Javeed Iqbal, Xuan Zhang, Julie M. Vose, Hongxia Cheng, Chengfeng Bi, Nanxi Jiang, Alyssa Bouska, Tian Tian, Kai Fu
Publikováno v:
British Journal of Haematology.
Autor:
Bhavana J. Dave, Pamela A. Althof, Rachel A. Harris, Diane L. Pickering, Jadd M. Stevens, Jennifer N. Sanmann, Lynette M. Smith
Publikováno v:
Leukemia research. 110
The clinical implications of deletions within chromosome 14q32 in CLL pathogenesis remain unclear. We examined the frequency of 14q32 deletions among CLL cases by karyotype and FISH, categorized the variation using genomic microarray, and assessed th
Publikováno v:
Leukemia research. 95
A relatively small subset of myeloid neoplasms involve rearrangements of cytoband 3q26.2. Such rearrangements are often in response to therapy and carry a poor prognosis. The ectopic expression of MECOM is the result of such translocations. To date,
Autor:
Pamela A. Althof, AZ VanDyke, SP Thayer, D Maroni, JN Sanmann, Prosenjit Mondal, Cassie J Liu, JD Price, JM Stevens
Publikováno v:
Cancer Research. 79:P2-03
Background: Autocrine motility factor (AMF) is secreted by cancer cells and acts in an autocrine or paracrine fashion to bind to its receptor, AMFR, at the cell surface of tumor cells. The AMF-AMFR pathway has been shown to promote proliferation, ant
Autor:
JM Stevens, AZ VanDyke, CE Grabow, JN Sanmann, JD Price, Pamela A. Althof, D Maroni, SP Thayer, Cassie J Liu
Publikováno v:
Cancer Research. 79:P3-01
Background: Most modern methods of detecting circulating tumor cells (CTCs) involve identifying cells with epithelial markers. This approach presents challenges, as not all epithelial cells found in circulation originate from the tumor and not all CT
Autor:
Michelle L. Varney, Bhavana J. Dave, Hesham M. Hassan, Rakesh Singh, Pamela A. Althof, Gabriel C. Caponetti, Kai Fu, Dennis D. Weisenburger
Publikováno v:
Cancer Research. 77:2157-2157
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma (NHL) and is curable in more than 60% of the cases. Despite long-term remission achieved with current therapies, relapse occurs in almost one-third of the case
Autor:
Rodney R. Miles, Mona S. Jahromi, Joshua D. Schiffman, Jonathan M. Downie, Sherrie L. Perkins, Pamela A. Althof, Phillip Barnette, Jennifer N. Sanmann, Patrick D. Lorimer, Vladimir Rodic, Warren G. Sanger, Michael G. Bayerl
Publikováno v:
British Journal of Haematology. 155:477-486
The majority of paediatric Burkitt lymphoma (pBL) patients that relapse will die of disease, but markers for this high-risk subset are unknown. MYC translocations characterize pBL, but additional genetic changes may relate to prognosis and serve as p
Autor:
Alan Norman Langnas, Wendy J. Grant, Martin Bast, Valerie Shostrom, James B. Ford, Pamela A. Althof, Kelly Erickson, Sanmann N Jennifer, Timothy C. Greiner, Peter F. Coccia
Publikováno v:
Blood. 132:5297-5297
Background: Post-Transplant Lymphoproliferative Disease (PTLD) is a heterogeneous disease that arises as a complication after solid organ transplants (SOT) and unusually after bone marrow transplants (BMT). PTLD is generally of recipient origin in SO
Autor:
Robert Tanner, Hagelstrom, James, Ford, Gwendolyn M, Reiser, Marilu, Nelson, Diane L, Pickering, Pamela A, Althof, Warren G, Sanger, Peter F, Coccia
Publikováno v:
Pediatric bloodcancer. 63(3)
Male breast cancer (MBC) is unusual, especially in young adults. Most cases of MBC as a secondary malignancy relate to the previous treatment with ionizing radiation. MBC can be associated with mutations in hereditary cancer predisposition syndrome g