Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Pamela A Kozlowski"'
Autor:
Anil Verma, Chase E Hawes, Sonny R Elizaldi, Justin C Smith, Dhivyaa Rajasundaram, Gabriel Kristian Pedersen, Xiaoying Shen, LaTonya D Williams, Georgia D Tomaras, Pamela A Kozlowski, Rama R Amara, Smita S Iyer
Publikováno v:
eLife, Vol 12 (2024)
CD4 T follicular helper cells (Tfh) are essential for establishing serological memory and have distinct helper attributes that impact both the quantity and quality of the antibody response. Insights into Tfh subsets that promote antibody persistence
Externí odkaz:
https://doaj.org/article/25f016ab6a0344d78af967a9cbf3f47a
Autor:
Caleb M Ardizzone, Hannah L Albritton, Rebecca A Lillis, Caitlyn E L Bagnetto, Li Shen, Lisa A Cavacini, Pamela A Kozlowski, Alison J Quayle
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258759 (2021)
The endocervix, the primary site of Chlamydia trachomatis (Ct) infection in women, has a unique repertoire of locally synthesized IgG and secretory IgA (SIgA) with contributions from serum IgG. Here, we assessed the ability of genital and serum-deriv
Externí odkaz:
https://doaj.org/article/d2881289f46540c5a3f7e24a73f687bb
Autor:
Hannah L Albritton, Pamela A Kozlowski, Rebecca A Lillis, Chris L McGowin, Julia D Siren, Stephanie N Taylor, Joyce A Ibana, Lyndsey R Buckner, Li Shen, Alison J Quayle
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183101 (2017)
Chlamydia trachomatis (CT) is the leading sexually transmitted bacterial infection. The continued global burden of CT infection strongly predicates the need for a vaccine to supplement current chlamydial control programs. The correlates of protection
Externí odkaz:
https://doaj.org/article/57f79375394b4515935723e1eb103a2f
Autor:
Rafiq Nabi, Zina Moldoveanu, Qing Wei, Elizabeth T Golub, Helen G Durkin, Ruth M Greenblatt, Betsy C Herold, Marek J Nowicki, Seble Kassaye, Michael W Cho, Abraham Pinter, Alan L Landay, Jiri Mestecky, Pamela A Kozlowski
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180245 (2017)
Mechanisms responsible for natural control of human immunodeficiency type 1 (HIV) replication in elite controllers (EC) remain incompletely defined. To determine if EC generate high quality HIV-specific IgA responses, we used Western blotting to comp
Externí odkaz:
https://doaj.org/article/c12b837a5fa64fd6afba030d2e100201
Autor:
Sama Adnan, R Keith Reeves, Jacqueline Gillis, Fay E Wong, Yi Yu, Jeremy V Camp, Qingsheng Li, Michelle Connole, Yuan Li, Michael Piatak, Jeffrey D Lifson, Wenjun Li, Brandon F Keele, Pamela A Kozlowski, Ronald C Desrosiers, Ashley T Haase, R Paul Johnson
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006104 (2016)
Defining the correlates of immune protection conferred by SIVΔnef, the most effective vaccine against SIV challenge, could enable the design of a protective vaccine against HIV infection. Here we provide a comprehensive assessment of immune response
Externí odkaz:
https://doaj.org/article/06b3afcb40fe45a695d045607398c274
Autor:
Lyndsey R Buckner, Angela M Amedee, Hannah L Albritton, Pamela A Kozlowski, Nedra Lacour, Chris L McGowin, Danny J Schust, Alison J Quayle
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146663 (2016)
Chlamydia trachomatis causes a predominantly asymptomatic, but generally inflammatory, genital infection that is associated with an increased risk for HIV acquisition. Endocervical epithelial cells provide the major niche for this obligate intracellu
Externí odkaz:
https://doaj.org/article/46cf557a467741299b88803eae5c2f37
Autor:
Venkata S. Bollimpelli, Pradeep B. J Reddy, Sailaja Gangadhara, Tysheena P. Charles, Samantha L. Burton, Gregory K. Tharp, Tiffany M. Styles, Celia C. Labranche, Justin C. Smith, Amit A. Upadhyay, Anusmita Sahoo, Traci Legere, Ayalnesh Shiferaw, Vijayakumar Velu, Tianwei Yu, Mark Tomai, John Vasilakos, Sudhir P. Kasturi, George M. Shaw, David Montefiori, Steven E. Bosinger, Pamela A. Kozlowski, Bali Pulendran, Cynthia A. Derdeyn, Eric Hunter, Rama R. Amara
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Route of immunization can markedly influence the quality of immune response. Here, we show that intradermal (ID) but not intramuscular (IM) modified vaccinia Ankara (MVA) vaccinations provide protection from acquisition of intravaginal tier2
Externí odkaz:
https://doaj.org/article/101d7faa095245b791894f88734b70d5
Autor:
Massimiliano Bissa, Veronica Galli, Luca Schifanella, Monica Vaccari, Mohammad Arif Rahman, Giacomo Gorini, Nicolò Binello, Sarkis Sarkis, Anna Gutowska, Isabela Silva de Castro, Melvin N. Doster, Ramona Moles, Guido Ferrari, Xiaoying Shen, Georgia D. Tomaras, David C. Montefiori, Kombo F. N’guessan, Dominic Paquin-Proulx, Pamela A. Kozlowski, David J. Venzon, Hyoyoung Choo-Wosoba, Matthew W. Breed, Joshua Kramer, Genoveffa Franchini
Publikováno v:
Vaccines, Vol 11, Iss 11, p 1662 (2023)
At the heart of the DNA/ALVAC/gp120/alum vaccine’s efficacy in the absence of neutralizing antibodies is a delicate balance of pro- and anti-inflammatory immune responses that effectively decreases the risk of SIVmac251 acquisition in macaques. Vac
Externí odkaz:
https://doaj.org/article/c79e712a0eef406bace853be5af64634
Autor:
Tiffany M. Styles, Sailaja Gangadhara, Pradeep B. J. Reddy, Anusmita Sahoo, Ayalensh Shiferaw, Sarah Welbourn, Pamela A. Kozlowski, Cynthia A. Derdeyn, Vijayakumar Velu, Rama Rao Amara
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Stabilized HIV envelope (Env) trimeric protein immunogens have been shown to induce strong autologous neutralizing antibody response. However, there is limited data on the immunogenicity and efficacy of stabilized Env expressed by a viral vector-base
Externí odkaz:
https://doaj.org/article/81f9a87b6bff43e3a8a1399b0ad63c82
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/69303b51de2c4dcea129f0439a26d134