Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pamela A Cote-Hammarlof"'
Autor:
Inês Fragata, Claudia Bank, Pamela A. Cote-Hammarlof, Konstantin B. Zeldovich, Julia M. Flynn, David Mavor, Daniel N. Bolon
Publikováno v:
Molecular Biology and Evolution
bioRxiv
Cote-Hammarlof, Pamela A; Fragata, Inês; Flynn, Julia; Mavor, David; Zeldovich, Konstantin B; Bank, Claudia; Bolon, Daniel N A (2021). The Adaptive Potential of the Middle Domain of Yeast Hsp90. Molecular Biology and Evolution, 38(2), pp. 368-379. Oxford University Press 10.1093/molbev/msaa211
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
bioRxiv
Cote-Hammarlof, Pamela A; Fragata, Inês; Flynn, Julia; Mavor, David; Zeldovich, Konstantin B; Bank, Claudia; Bolon, Daniel N A (2021). The Adaptive Potential of the Middle Domain of Yeast Hsp90. Molecular Biology and Evolution, 38(2), pp. 368-379. Oxford University Press 10.1093/molbev/msaa211
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The distribution of fitness effects (DFEs) of new mutations across different environments quantifies the potential for adaptation in a given environment and its cost in others. So far, results regarding the cost of adaptation across environments have
Autor:
Isidora N Stankovic, Anastasia Gant Kanegusuku, Pamela A Cote-Hammarlof, Priscilla H Yong, Christine A. White-Ziegler
Publikováno v:
Journal of Bacteriology
One of the first environmental cues sensed by a microbe as it enters a human host is an upshift in temperature to 37°C. In this dynamic time point analysis, we demonstrate that this environmental transition rapidly signals a multitude of gene expres
Autor:
Claudia Bank, Daniel N. Bolon, Julia M. Flynn, David Mavor, Carl Hollins, Inês Fragata, Pamela A. Cote-Hammarlof, Ammeret Rossouw
Publikováno v:
eLife, Vol 9 (2020)
eLife
Flynn, Julia M; Rossouw, Ammeret; Cote-Hammarlof, Pamela; Fragata, Inês; Mavor, David; Hollins, Carl; Bank, Claudia; Bolon, Daniel NA (2020). Comprehensive fitness maps of Hsp90 show widespread environmental dependence. eLife, 9 eLife Sciences Publications 10.7554/eLife.53810
eLife
Flynn, Julia M; Rossouw, Ammeret; Cote-Hammarlof, Pamela; Fragata, Inês; Mavor, David; Hollins, Carl; Bank, Claudia; Bolon, Daniel NA (2020). Comprehensive fitness maps of Hsp90 show widespread environmental dependence. eLife, 9 eLife Sciences Publications 10.7554/eLife.53810
Gene-environment interactions have long been theorized to influence molecular evolution. However, the environmental dependence of most mutations remains unknown. Using deep mutational scanning, we engineered yeast with all 44,604 single codon changes