Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Pamela, Somers"'
Publikováno v:
Cells Tissues Organs. 204:270-282
To date, a completely in vitro repopulated tissue-engineered heart valve has not been developed. This study focused on sequentially seeding 2 cell populations onto porcine decellularized heart valve leaflets (HVL) and pericardia (PER) to obtain fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffaa4d6fcb12008f0ba988d5a8c4d44
https://doi.org/10.1159/000480660
https://doi.org/10.1159/000480660
Autor:
Annelies Roosens, Guido Van Nooten, Pamela Somers, Filip De Somer, Víctor Carriel, Ria Cornelissen
Publikováno v:
Annals of Biomedical Engineering. 44:2827-2839
To date an optimal decellularization protocol of heart valve leaflets (HVL) and pericardia (PER) with an adequate preservation of the extracellular matrix (ECM) is still lacking. This study compares a 4 day Triton X-100-based protocol with faster SDC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb19415c92910b7b98f306b349ca1a00
https://doi.org/10.1007/s10439-016-1555-0
https://doi.org/10.1007/s10439-016-1555-0
Publikováno v:
Journal of the Mechanical Behavior of Biomedical Materials. 13:78-84
Freshly excised porcine aortic heart valve cusps were subjected to a uni-axial flexural indentation test, from which the rupture characteristics and a functional stiffness parameter were determined. It was found that the flexural mechanical propertie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7afc3639d1b1003f9e8f9301ca121076
https://doi.org/10.1016/j.jmbbm.2012.04.009
https://doi.org/10.1016/j.jmbbm.2012.04.009
Autor:
Thierry Bové, Filip De Somer, Guido Van Nooten, Patrick Wouters, Stefan De Hert, Daniel Devos, Pamela Somers, Stefaan Bouchez
Publikováno v:
Journal of the American College of Cardiology. 60:64-71
Objectives This study investigates the contribution of infundibular versus pulmonary valve (PV) dysfunction on right ventricular (RV) function in a porcine model. Background Clinical outcome after repair of tetralogy of Fallot is determined by the ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655719915c78c819c3ec9edfca26a280
https://doi.org/10.1016/j.jacc.2012.03.035
https://doi.org/10.1016/j.jacc.2012.03.035
Autor:
G. Van Nooten, E. Nollet, Pamela Somers, Hubert Thierens, L. Robyns, F De Somer, Maria Cornelissen
Publikováno v:
Cell Proliferation. 45:378-385
Objective The aim of this study was to repopulate decellularized heart valve matrices with ovine mesenchymal stem cells (oMSCs) by the use of platelet gel (PG) supernatant, a storage vehicle for growth factors. Methods oMSCs were exposed to different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26713f2788b292a43f1ad9752c5250fa
https://doi.org/10.1111/j.1365-2184.2012.00830.x
https://doi.org/10.1111/j.1365-2184.2012.00830.x
Publikováno v:
Artificial Cells, Blood Substitutes, and Biotechnology. 40:151-162
Currently used decellularization procedures have negative effects on extracellular matrix (ECM) integrity. The objective of this study is to evaluate four decellularization methods and their effect on the collagen ultrastructure, mechanical behavior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c6fc56d6c80d595232f694f38a12d7
https://doi.org/10.3109/10731199.2011.637925
https://doi.org/10.3109/10731199.2011.637925
Autor:
Filip De Somer, Pamela Somers, Maria Cornelissen, Guido Van Nooten, Eric Cox, Koen Chiers, Claude Cuvelier, Marc Verloo
Publikováno v:
Tissue Engineering Part A. 15:3597-3604
OBJECTIVES: Xenogenic extracellular heart valve matrices have been suggested as scaffolds for tissue engineering. However, these matrices are immunogenic and stimulate an intense cell-mediated immune response and calcification. Mitigating the immunog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793dd301476ffd462e324d6c2144a729
https://doi.org/10.1089/ten.tea.2008.0690
https://doi.org/10.1089/ten.tea.2008.0690
Publikováno v:
Journal of Biomedical Materials Research Part A. :1106-1112
The study evaluates the mechanical and chemical characteristics of autologous surgical glue made by mixing ultrafiltered plasma with glutaraldehyde (GTA). Human albumin 200 g/L mixed with different concentrations of GTA (25, 50, 75, or 100 g/L) was u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b558998dcf0fdfaeeeace288af21da99
https://doi.org/10.1002/jbm.a.31705
https://doi.org/10.1002/jbm.a.31705
Autor:
Yves Van Belleghem, Pamela Somers, Stefaan Jacobs, Kishan Narine, Guido Van Nooten, Filip De Somer, Ramses G Forsyth
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 134(2):415-423
Objective The aim of the study was to evaluate the safety and efficacy of an autologous surgical tissue adhesive. Methods Autologous glue was made out of canine concentrated plasma proteins mixed with 7.5% glutaraldehyde. Tensile strength and cytotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feffdbc68fe03f968e20b0fda2368dd1
Autor:
Sebstiaan de Winter, Ronald Hamers, Pim J. de Feijter, Stefan Verheye, Glenn Van Langenhove, Jos R.T.C. Roelandt, Michiel W.M. Knaapen, Evelyn Regar, Jurgen Ligthart, Iddo Heller, Nico Bruining, Pamela Somers, Patrick W. Serruys
Publikováno v:
Catheterization and Cardiovascular Interventions, 70(7), 968-978. Wiley-Liss Inc.
Objective: To validate automated and quantitative three-dimensional analysis of coronary plaque composition using intracoronary ultrasound (ICUS). Background: ICUS displays different tissue components based on their acoustic properties in 256 grey-le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95c83bb2c0ade10b66e8a89a9e0f0ee
https://doi.org/10.1002/ccd.21310
https://doi.org/10.1002/ccd.21310