Výsledky vyhledávání - "Pamela, Esposito"

Corticotropin-releasing factor (CRF) can directly affect brain microvessel endothelial cells

Autor: Richard Letourneau, Pamela Esposito, Stanley Jacobson, Subimal Basu, Theoharis C. Theoharides

Publikováno v: Brain Research. 968:192-198

Stress activates the hypothalamic–pituitary–adrenal (HPA) axis through release of corticotropin releasing factor (CRF), leading to production of glucocorticoids that down regulate immune responses. However, acute stress via CRF also has pro-infla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791a17a1bfe54bc21c5f864ff0ad46a9
https://doi.org/10.1016/s0006-8993(03)02237-6

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Stress-induced dura vascular permeability does not develop in mast cell-deficient and neurokinin-1 receptor knockout mice

Autor: Man Huang, Josef Priller, Theoharis C. Theoharides, Norma P. Gerard, Kristiana Kandere-Grzybowska, Pamela Esposito, Daniela Gheorghe

Publikováno v: Brain Research, 980(2), 213-220. Elsevier
Kandere-Grzybowska, K, Gheorghe, D, Priller, J, Esposito, P, Huang, M, Gerard, N & Theoharides, T C 2003, ' Stress-induced dura vascular permeability does not develop in mast cell-deficient and neurokinin-1 receptor knockout mice ', Brain Research, vol. 980, no. 2, pp. 213-220 . https://doi.org/10.1016/S0006-8993(03)02975-5

Migraine headaches are often precipitated by stress and seem to involve neurogenic inflammation (NI) of the dura mater associated with the sensation of throbbing pain. Trigeminal nerve stimulation had been reported to activate rat dura mast cells and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2863b344a4f54eebaa8ef6c8b54cba3
https://doi.org/10.1016/s0006-8993(03)02975-5

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Acute stress shortens the time to onset of experimental allergic encephalomyelitis in SJL/J mice

Autor: Raymond J. Connolly, N. Chandler, Stanley Jacobson, Theoharis C. Theoharides, Pamela Esposito

Publikováno v: Brain, Behavior, and Immunity. 16:757-763

Experimental allergic encephalomyelitis (EAE) is a murine model of multiple sclerosis (MS), an inflammatory condition of the central nervous system (CNS) resulting in focal demyelination due to the infiltration of sensitized T-leukocytes through the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ce9e057943d09021b9983d4efb0016
https://doi.org/10.1016/s0889-1591(02)00028-4

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Non-invasive assessment of blood–brain barrier (BBB) permeability using a gamma camera to detect 99technetium-gluceptate extravasation in rat brain

Autor: Theoharis C. Theoharides, Stanley Jacobson, Pamela Esposito, Raymond J. Connolly, Daniela Gheorghe

Publikováno v: Brain Research Protocols. 8:143-149

The blood–brain barrier (BBB) is a complex structure of endothelial cells, astroglia, pericytes, and perivascular macrophages enclosed by basal lamina. The BBB regulates the entry of blood-borne molecules and cells into the brain, but it is disrupt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5770390b3173736c7d16f0ff4d6a900
https://doi.org/10.1016/s1385-299x(01)00104-0

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Acute stress increases permeability of the blood–brain-barrier through activation of brain mast cells

Autor: Pamela Esposito, Kristiana Kandere, Daniela Gheorghe, Theoharis C. Theoharides, Stanley Jacobson, Xinzhu Pang, Raymond J. Connolly

Publikováno v: Brain Research. 888:117-127

Disruption of the blood-brain-barrier (BBB) is important in the pathophysiology of various inflammatory conditions of the central nervous system (CNS), such as multiple sclerosis (MS), in which breakdown of the BBB precedes any clinical or pathologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332052074a8fd0d29faef22fd85eea89
https://doi.org/10.1016/s0006-8993(00)03026-2

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Corticotropin-releasing hormone and brain mast cells regulate blood-brain-barrier permeability induced by acute stress

Autor: Pamela Esposito, Nathan Chandler, Kristiana Kandere, Subimal Basu, Stanley Jacobson, David Tutor, Theoharis C. Theoharides, Raymond J. Connolly

Publikováno v: The Journal of pharmacology and experimental therapeutics. 303(3)

Stress activates the hypothalamic-pituitary-adrenal axis through release of corticotropin releasing hormone (CRH), leading to production of glucocorticoids that down-regulate immune responses. Acute stress, however, also has proinflammatory effects t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3199eea7192d1e399e57e1a946048654
https://pubmed.ncbi.nlm.nih.gov/12438528

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Acute stress results in skin corticotropin-releasing hormone secretion, mast cell activation and vascular permeability, an effect mimicked by intradermal corticotropin-releasing hormone and inhibited by histamine-1 receptor antagonists

Autor: Theoharis C. Theoharides, Duraisamy Kempuraj, Man Huang, Pamela Esposito, William Boucher, Michael Lytinas

Publikováno v: International archives of allergy and immunology. 130(3)

Background: Mast cells play an important role in allergic inflammation by releasing vasoactive molecules, proteases and cytokines. Corticotropin-releasing hormone (CRH) and its structural analogue urocortin (Ucn) were shown to trigger skin mast cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3243a40afa21b3082bddcc11f8ddc72a
https://pubmed.ncbi.nlm.nih.gov/12660427

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