Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Pamarthi F. Mohan"'
Autor:
Sherman Bloom, Pamarthi F. Mohan
Publikováno v:
Cardiovascular Pathology. 6:287-291
Factors that determine the wide variation in the severity of isoproterenol-induced myocardial necrosis (ISO-MN) are numerous and poorly defined. We have investigated the role of age, body weight, food intake, and genetic strain differences on vulnera
Autor:
March D. Ard, Pamarthi F. Mohan
Publikováno v:
Glia. 17:259-262
The effect of lipoproteins on adult rat CNS microglial nitric oxide (NO) production was studied. Incubation of cultured microglia with very low density lipoprotein (VLDL) for 48 h induced a 13-fold increase in NO production, compared with control. Ho
Autor:
Marc S. Jacobson, Pamarthi F. Mohan
Publikováno v:
The American Journal of the Medical Sciences. 306:10-15
To understand the anti-atherosclerotic mechanism of the steroid dehydroepiandrosterone (DHEA), the effect of DHEA on rat peritoneal macrophage superoxide generation was studied. Dehydroepiandrosterone (12.5 to 50 μ M) inhibited digitonin-stimulated
Autor:
Margot P. Cleary, Pamarthi F. Mohan
Publikováno v:
The Journal of Nutrition. 121:240-250
Administration of dehydroepiandrosterone (DHEA) to rats results in alterations in liver and serum factors. This study was undertaken to determine the earliest metabolic change(s) associated with DHEA treatment. Serum cholesterol, triacylglycerol, glu
Autor:
Pamarthi F. Mohan, Sherman Bloom
Publikováno v:
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 8(5)
The cardiotoxic effect of isoproterenol (ISO) is associated with, and possibly due to, calcium overload. Prior work suggests that calcium entry into cardiac myocytes after ISO administration occurs in two phases: an early rapid phase, followed by a s
Autor:
Marc S. Jacobson, Pamarthi F. Mohan
Publikováno v:
Cell biochemistry and function. 13(2)
Superoxide production by macrophages and leukocytes may have an important role in atherogenesis. Whether lipoproteins modulate the superoxide production of these cells is not clear. Therefore, the effect of lipoproteins on the production of superoxid
Autor:
Pamarthi F. Mohan, Margot P. Cleary
Publikováno v:
Steroids. 57(5)
Experiments were conducted to determine if dehydroepiandrosterone (DHEA) specifically binds to liver nuclei or interferes in the binding of other steroid hormones. Hepatocytes were isolated from obese, female Zucker rats that were treated with and wi
Publikováno v:
The British journal of nutrition. 66(2)
The aim of the present investigation was to study the effects of fish oil feeding in obese Zucker rats to establish its suitability as an animal model of hyperlipidaemia, and to understand the possible mechanism of fish oil-induced perturbations in c
Publikováno v:
The Journal of nutrition. 120(9)
Previous studies showed that administration of dehydroepiandrosterone (DHEA) to lean and genetically obese Zucker rats reduced body weight. In the present experiments, the effect of DHEA treatment in rats with diet-induced obesity was evaluated. In e
Autor:
Pamarthi F. Mohan, Margot P. Cleary
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 255:E1-E8
Lean and obese Zucker rats, 7-8 wk of age, were treated with dehydroepiandrosterone (DHEA) for either 3 or 7 days to determine the initial cellular event(s) that might be responsible for the antiobesity activity of DHEA. Epididymal, retroperitoneal,