Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pam Witte"'
Autor:
Thomas Manley, Rachel M. Gittelman, Lance Baldo, Hans Nesse, Sudeb C. Dalai, Ian M. Kaplan, Caroline Taromino, John Alsobrook, Megan Herndon, Kipp Akers, Tera Eerkes, Emily Svejnoha, Sarah Duffy, Pam Witte, Jia Qadeer, Jennifer N. Dines, Thomas M. Snyder, Pashmi Vaney, Lynell Skewis, Anthony Monteforte, Cristina Wolf, Sally Howard
BackgroundWhile diagnostic, therapeutic, and vaccine development in the COVID-19 pandemic has proceeded at unprecedented speed and scale, critical gaps remain in our understanding of the immune response to SARS-CoV-2. Current diagnostic strategies, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2fa83119b2e6922525c69a98284343d
https://doi.org/10.1101/2021.01.06.21249345
https://doi.org/10.1101/2021.01.06.21249345
Autor:
Pam Witte, Alex B. Burgin, Jan Abendroth, Anca M. Segall, Timothy K. Craig, Forest Rohwer, Robert Edwards, Jeremy A. Frank, Merry Youle, Don Lorimer
Publikováno v:
The ISME Journal
Bacteriophages encode auxiliary metabolic genes that support more efficient phage replication. For example, cyanophages carry several genes to maintain host photosynthesis throughout infection, shuttling the energy and reducing power generated away f
Autor:
Thomas E. Edwards, Peter J. Myler, Pam Witte, Loren Baugh, Wesley C. Van Voorhis, Ruth Baydo, Kaitlin Thompkins, Bart L. Staker, Isabelle Phan, Donald D. Lorimer, Jameson Bullen, Christoph Grundner, Banumathi Sankaran, Jan Abendroth, Matthew C. Clifton
Publikováno v:
Journal of structural and functional genomics. 16(2)
The methylmalonyl Co-A mutase-associated GTPase MeaB from Methylobacterium extorquens is involved in glyoxylate regulation and required for growth. In humans, mutations in the homolog methylmalonic aciduria associated protein (MMAA) cause methylmalon
Autor:
Mark E. Gurney, Bart L. Staker, Jasbir Singh, Pam Witte, Alex B. Burgin, Timothy J. Hagen, Margret Thorsteinsdottir, Jon Mar Bjornsson, Sigrun Hrafnsdottir, Olafur T. Magnusson, Lance Stewart, Alex S. Kiselyov
Publikováno v:
Nature biotechnology. 28(1)
Phosphodiesterase 4 (PDE4), the primary cAMP-hydrolyzing enzyme in cells, is a promising drug target for a wide range of conditions. Here we present seven co-crystal structures of PDE4 and bound inhibitors that show the regulatory domain closed acros