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pro vyhledávání: '"Pam S. Scott"'
Autor:
E. Jon Jacobsen, Mark A. Mitchell, Susan K. Hendges, Kenneth L. Belonga, Louis L. Skaletzky, Lindsay S. Stelzer, Thomas. J. Lindberg, Edward L. Fritzen, Heinrich J. Schostarez, Theresa J. O'Sullivan, Linda L. Maggiora, Christopher W. Stuchly, Alice L. Laborde, Marc F. Kubicek, Roger A. Poorman, Joan M. Beck, Henry R. Miller, Gary L. Petzold, Pam S. Scott, Scott E. Truesdell, Tanya L. Wallace, John W. Wilks, Christopher Fisher, Linda V. Goodman, Paul S. Kaytes, Stephen R. Ledbetter, Elaine A. Powers, Gabriel Vogeli, John E. Mott, Catherine M. Trepod, Douglas J. Staples, Eric T. Baldwin, Barry C. Finzel
Publikováno v:
Journal of medicinal chemistry. 42(9)
The synthesis and enzyme inhibition data for a series of thiadiazole urea matrix metalloproteinase (MMP) inhibitors are described. A broad screening effort was utilized to identify several thiadiazoles which were weak inhibitors of stromelysin. Optim