Výsledky vyhledávání - "Pam S, Schwartz"

Autor: Michael K, Manion, John, Fry, Pam S, Schwartz, David M, Hockenbery

Publikováno v: Current opinion in investigational drugs (London, England : 2000). 7(12)

Cancer cells with elevated levels of Bcl-2 and the related anti-apoptotic proteins Bcl-x(L), Mcl-1 and Bcl-W are broadly resistant to standard anticancer drugs and other therapeutic modalities. Antisense oligodeoxynucleotides and, more recently, smal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::88dc19c067c54d1d3cba4bcec88d0591
https://pubmed.ncbi.nlm.nih.gov/17209525

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Promises and challenges of targeting Bcl-2 anti-apoptotic proteins for cancer therapy

Autor: Michael Keoni Manion, Jason W. O'Neill, Pam S. Schwartz, David M. Hockenbery

Publikováno v: Biochimica et biophysica acta. 1705(1)

Cancer cells with elevated levels of BCL-2 and related survival proteins are broadly resistant to cytotoxic agents. Antisense oligodeoxynucleotides, and more recently small molecule ligands for BCL-2 and BCL-XL, are directly cytotoxic or synergistic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32644b94eabb6f511b44042a37c51f48
https://pubmed.ncbi.nlm.nih.gov/15585172

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