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Autor:
Brian Peter SmithKline Beecham Pharm Clarke, Moreno Galleni, David J. Payne, Bateson John Hargreaves, Ceri Lewis, Christy A. Cheever, Sherin S. Abdel-Meguid, Pam Rowling, Nestor O. Concha, Stewart C. Pearson, Jean-Marie Frere, Cheryl A. Janson
Publikováno v:
Biochemistry. 39:4288-4298
Metallo beta-lactamase enzymes confer antibiotic resistance to bacteria by catalyzing the hydrolysis of beta-lactam antibiotics. This relatively new form of resistance is spreading unchallenged as there is a current lack of potent and selective inhib