Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pam R. Fain"'
Autor:
Marshall W. Anderson, Joan E. Bailey-Wilson, Colette Gaba, Teresa Coons, Ming You, Diptasri Mandal, Henry Rothschild, Dong Zeng, Jonathan S. Wiest, John Minna, Adi Gazdar, Pam R. Fain, Ann G. Schwartz, Ping Yang, Mariza A. de Andrade, Juwon Lee, Elena Kupert, Yafang Li, Susan M. Pinney, Christopher I. Amos
Supplementary Figures 1-3, Tables 1-2 from A Susceptibility Locus on Chromosome 6q Greatly Increases Lung Cancer Risk among Light and Never Smokers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c1fc2136eb17a5f50e80591189c3c4
https://doi.org/10.1158/0008-5472.22387146.v1
https://doi.org/10.1158/0008-5472.22387146.v1
Autor:
Peter A. Gottlieb, Peter R. Baker, Janet C. Siebert, Marian Rewers, Priyaanka Nanduri, Pam R. Fain, Taylor M. Triolo, Taylor K. Armstrong, Sunanda R. Babu, Erin E. Baschal, George S. Eisenbarth, Jennifer M. Barker
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 96:2154-2162
Autoimmune Addison's disease (AD) is the major cause of primary adrenal failure in developed nations. Autoantibodies to 21-hydroxylase (21OH-AA) are associated with increased risk of progression to AD. Highest genetic risk is associated with the Majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a215f0025989bc133725b90f3d1679b
https://doi.org/10.1210/jc.2010-2964
https://doi.org/10.1210/jc.2010-2964
Autor:
Carani B. Sanjeevi, Pam R. Fain, Liping Yu, Y.S. Park, Marian Rewers, David T. Robles, George S. Eisenbarth, Peter A. Gottlieb
Publikováno v:
Tissue Antigens. 60:155-163
Intra-MHC sequences including MHC class I chain-related genes (MICAs), D6S273 and D6S2223 are associated with autoimmune diseases in addition to HLA class II. In the current study, we ascertained the haplotypes of 57 Caucasian patients with Addison's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aaaf880d697ca6e582cd31383252848
https://doi.org/10.1034/j.1399-0039.2002.600206.x
https://doi.org/10.1034/j.1399-0039.2002.600206.x
Autor:
Fei Bao, Liping Yu, Teodorica L. Bugawan, Sunanda R. Babu, Pnina Vardi, D Tiosano, Charles F. Verge, George S. Eisenbarth, Pam R. Fain, Henry A. Erlich
Publikováno v:
Journal of Clinical Investigation. 102:1569-1575
Based on a genomic search for linkage, a locus contributing to type 1 diabetes in a large Bedouin Arab family (19 affected relatives) maps to the long arm of chromosome 10 (10q25; nonparametric linkage = 4.99; P = 0.00004). All affected relatives car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c857d6b96790a5d511cd9e147e7b064f
https://doi.org/10.1172/jci3379
https://doi.org/10.1172/jci3379
Autor:
Marian Rewers, George S. Eisenbarth, Janet C. Siebert, Taylor M. Triolo, Sunanda R. Babu, Taylor K. Armstrong, Peter R. Baker, Pam R. Fain, Jennifer M. Barker, Priyaanka Nanduri, Peter A. Gottlieb, Erin E. Baschal
Publikováno v:
The Journal of clinical endocrinology and metabolism. 95(10)
Context: Multiple autoimmune disorders (e.g. Addison’s disease, type 1 diabetes, celiac disease) are associated with HLA-DR3, but it is likely that alleles of additional genes in linkage disequilibrium with HLA-DRB1 contribute to disease. Objective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916487034a72c90086572243871d1296
https://pubmed.ncbi.nlm.nih.gov/20631027
https://pubmed.ncbi.nlm.nih.gov/20631027
Autor:
John D. Minna, Pam R. Fain, Elena Kupert, Teresa A. Coons, Juwon Lee, Jonathan S. Wiest, Susan M. Pinney, Christopher I. Amos, Ann G. Schwartz, Colette Gaba, Adi F. Gazdar, Dong Zeng, Yafang Li, Diptasri Mandal, Henry Rothschild, Joan E. Bailey-Wilson, Ming You, Mariza de Andrade, Marshall W. Anderson, Ping Yang
Publikováno v:
Cancer research. 70(6)
Cigarette smoking is the major cause for lung cancer, but genetic factors also affect susceptibility. We studied families that included multiple relatives affected by lung cancer. Results from linkage analysis showed strong evidence that a region of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62cd5d34f728a962ec6e2414ed9b657
https://pubmed.ncbi.nlm.nih.gov/20215501
https://pubmed.ncbi.nlm.nih.gov/20215501
Autor:
Eugene E. Wolfel, Dmi Dao, William P. McNair, Luisa Mestroni, Pam R. Fain, Lisa Ku, Matthew R.G. Taylor
Publikováno v:
Circulation. 110(15)
Background— We studied a large family affected by an autosomal dominant cardiac conduction disorder associated with sinus node dysfunction, arrhythmia, and right and occasionally left ventricular dilatation and dysfunction. Previous linkage analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7ed8e11c30f771af9701b750f82b58
https://pubmed.ncbi.nlm.nih.gov/15998690
https://pubmed.ncbi.nlm.nih.gov/15998690
Publikováno v:
Journal of Autoimmunity
Journal of Autoimmunity, Elsevier, 2003, 21 (2), pp.93-98. ⟨10.1016/S0896-8411(03)00097-0⟩
Journal of Autoimmunity, Elsevier, 2003, 21 (2), pp.93-98. ⟨10.1016/S0896-8411(03)00097-0⟩
International audience; Type 1A (immune mediated) diabetes is genetically heterogeneous with important examples for man and animal models with major mutations (autosomal recessive and X-linked recessive) identified as well as oligogenic/polygenic inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd88f76a3d0a2a067c08953faf1757d
https://hal-pasteur.archives-ouvertes.fr/pasteur-01643793
https://hal-pasteur.archives-ouvertes.fr/pasteur-01643793
Publikováno v:
Journal of Investigative Medicine. 53:S149.1-S149
Addison9s disease (AD) is a rare autoimmune disorder affecting approximately 1/10,000 in the general population. It typically occurs sporadically with a single member of a family affected (simplex families). Rarely, multiple members of a family can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60b31c2116522bdd97f699ede0c8340c
https://doi.org/10.2310/6650.2005.00005.402
https://doi.org/10.2310/6650.2005.00005.402
Autor:
Christine Klein, Qian Liu, Henry Rothschild, Daniela Seminara, Diptasri Mandal, Jeffrey E. Lee, D. Zeng, M. De Andrade, Pam R. Fain, Jonathan S. Wiest, Antonio Perez, X. Zhou, Marshall W. Anderson, Colette Gaba, Christopher I. Amos, Elena Kupert, Wilbur A. Franklin, Teresa A. Coons, Susan M. Pinney, Adi F. Gazdar, Ann G. Schwartz, Q. Zhang, Gloria M. Petersen, Joan E. Bailey-Wilson, John D. Minna, Ming You, Joshua P. Slusser
Publikováno v:
The American Journal of Human Genetics. (3):460-474
Lung cancer is a major cause of death in the United States and other countries. The risk of lung cancer is greatly increased by cigarette smoking and by certain occupational exposures, but familial factors also clearly play a major role. To identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0c8f85ea4250ce7b3229d527b296f2