Zobrazeno 1 - 5 of 5 pro vyhledávání: '"Pam F. Jones"'
1
Mathematical and computational models of drug transport in tumours
Autor: Roger M. Phillips, Nagarajan Periasamy, Matthew E. Hubbard, Paul M. Loadman, Pam F. Jones, C. M. Groh, Chris Twelves, Stephen W. Smye, Brian D. Sleeman
Publikováno v: Journal of the Royal Society, Interface. 11(94)
The ability to predict how far a drug will penetrate into the tumour microenvironment within its pharmacokinetic (PK) lifespan would provide valuable information about therapeutic response. As the PK profile is directly related to the route and sched
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cdd016e1a3f953b24d2b7cd1becd24
https://pubmed.ncbi.nlm.nih.gov/24621814
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3
Abstract 1572: Characterising the tumor vasculature in vivo in mouse models of colorectal cancer using contrast enhanced high-frequency ultrasound
Autor: Pam F. Jones, John A. Evans, Alex F. Markham, PL Coletta, Gemma Marston, Mark A. Hull
Publikováno v: Cancer Research. 71:1572-1572
Angiogenesis is essential for tumours to grow beyond a few millimetres in size and to metastasise, making it an attractive target for both cancer imaging and therapeutic intervention. Although microvessel density (MVD) is routinely used to assess tum
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4609650179e9402039918af3b5214ad
https://doi.org/10.1158/1538-7445.am2011-1572
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4
Abstract 5507: The development and evaluation of a model for assessing convective fluid flow through multicell layers in vitro
Autor: Brian D. Sleeman, Roger M. Phillips, Pam F. Jones, Nagarajan Periasamy, Stephen W. Smye, C.J. Evans, Chris J. Twelves, Paul M. Loadman
Publikováno v: Cancer Research. 70:5507-5507
Introduction: Elevated interstitial fluid pressure (IFP) is a characteristic feature of many solid tumours. One consequence of elevated IFP is that the normal process of convective fluid flow through tissues is impeded, and this is now recognised as
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e690abd107d4f9401c1f169670c4f667
https://doi.org/10.1158/1538-7445.am10-5507
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