Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Palte RL"'
Autor:
Logan KM; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Kaplan W; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Simov V; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Zhou H; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Li D; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Torres L; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Morriello GJ; Merck & Co., Inc., 126 E. Lincoln Ave., Rahway, New Jersey 07065, United States., Acton JJ; Merck & Co., Inc., 126 E. Lincoln Ave., Rahway, New Jersey 07065, United States., Pio B; Merck & Co., Inc., 126 E. Lincoln Ave., Rahway, New Jersey 07065, United States., Chen YH; Merck & Co., Inc., 126 E. Lincoln Ave., Rahway, New Jersey 07065, United States., Keylor MH; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Johnson R; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Kattar SD; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Chau R; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Yan X; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Ardolino M; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Zarate C; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Otte KM; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Palte RL; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Xiong T; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., McMinn SE; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Lin S; Merck & Co., Inc., 126 E. Lincoln Ave., Rahway, New Jersey 07065, United States., Neelamkavil SF; Merck & Co., Inc., 126 E. Lincoln Ave., Rahway, New Jersey 07065, United States., Liu P; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Su J; Merck & Co., Inc., 126 E. Lincoln Ave., Rahway, New Jersey 07065, United States., Hegde LG; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Woodhouse JD; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Moy LY; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Ciaccio PJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Piesvaux J; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Zebisch M; Evotec (U.K.) Ltd., 90 Park Drive, Milton Park, Abingdon OX14 4RZ, Oxfordshire, U.K., Henry C; Evotec (U.K.) Ltd., 90 Park Drive, Milton Park, Abingdon OX14 4RZ, Oxfordshire, U.K., Barker J; Evotec (U.K.) Ltd., 90 Park Drive, Milton Park, Abingdon OX14 4RZ, Oxfordshire, U.K., Wood HB; Merck & Co., Inc., 126 E. Lincoln Ave., Rahway, New Jersey 07065, United States., Kennedy ME; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., DiMauro EF; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Fell MJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Fuller PH; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2024 Sep 26; Vol. 67 (18), pp. 16807-16819. Date of Electronic Publication: 2024 Sep 04.
Autor:
Kattar SD; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Gulati A; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Margrey KA; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Keylor MH; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Ardolino M; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Yan X; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Johnson R; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Palte RL; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., McMinn SE; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Nogle L; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Su J; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Xiao D; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Piesvaux J; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Lee S; Merck & Co., Inc., 126 E. Lincoln Ave., Rahway, New Jersey 07065, United States., Hegde LG; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Woodhouse JD; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Faltus R; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Moy LY; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Xiong T; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Ciaccio PJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Pearson K; Merck & Co., Inc., 770 Sumneytown Pike., West Point, Pennsylvania 19486, United States., Patel M; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Otte KM; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Leyns CEG; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Kennedy ME; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Bennett DJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., DiMauro EF; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Fell MJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Fuller PH; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2023 Nov 09; Vol. 66 (21), pp. 14912-14927. Date of Electronic Publication: 2023 Oct 20.
Autor:
Gathiaka S; Computational & Structural Chemistry, Merck & Co., Inc., Boston, MA 02115, USA. Electronic address: symon.gathiaka@gmail.com., Palte RL; Computational & Structural Chemistry, Merck & Co., Inc., Boston, MA 02115, USA., So SS; Computational & Structural Chemistry, Merck & Co., Inc., Kenilworth, NJ 07033, USA., Chai X; Quantitative Biosciences, Merck & Co., Inc., Boston, NJ 02115, USA., Richard Miller J; Quantitative Biosciences, Merck & Co., Inc., Boston, MA 02115, USA., Kuvelkar R; Screening, Target and Compound Profiling, Merck & Co., Inc., Kenilworth, NJ 07033, USA., Wen X; Computational & Structural Chemistry, Merck & Co., Inc., Boston, MA 02115, USA., Cifelli S; Screening, Target and Compound Profiling, Merck & Co., Inc., Kenilworth, NJ 07033, USA., Kreamer A; Screening, Target and Compound Profiling, Merck & Co., Inc., Kenilworth, NJ 07033, USA., Liaw A; Biometrics Research, Merck & Co., Inc., Rahway, 90 E Scott Ave, Rahway, NJ 07065, USA., McLaren DG; Computational & Structural Chemistry, Merck & Co., Inc., Boston, MA 02115, USA., Fischer C; Discovery Chemistry, Merck & Co., Inc., Boston, MA 02115, USA.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2023 Mar 15; Vol. 84, pp. 129193. Date of Electronic Publication: 2023 Feb 21.
Autor:
Candito DA; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Simov V; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Gulati A; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Kattar S; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Chau RW; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Lapointe BT; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Methot JL; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., DeMong DE; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Graham TH; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Kurukulasuriya R; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Keylor MH; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Tong L; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Morriello GJ; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Acton JJ; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Pio B; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Liu W; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Scott JD; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Ardolino MJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Martinot TA; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Maddess ML; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Yan X; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Gunaydin H; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Palte RL; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., McMinn SE; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Nogle L; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Yu H; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Minnihan EC; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Lesburg CA; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Liu P; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Su J; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Hegde LG; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Moy LY; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Woodhouse JD; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Faltus R; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Xiong T; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Ciaccio P; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Piesvaux JA; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Otte KM; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Kennedy ME; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Bennett DJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., DiMauro EF; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Fell MJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Neelamkavil S; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Wood HB; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Fuller PH; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Ellis JM; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2022 Dec 22; Vol. 65 (24), pp. 16801-16817. Date of Electronic Publication: 2022 Dec 07.
Autor:
Kawamura S; Discovery Chemistry, Merck & Co., Inc., Boston, MA 02115, United States. Electronic address: shuhei.kawamura@merck.com., Palte RL; Computational and Structural Chemistry, Merck & Co., Inc., Boston, MA 02115, United States., Kim HY; NMR Structure Elucidation, Process and Analytical Chemistry, Merck & Co., Inc., Boston, MA 02115, United States., Saurí J; NMR Structure Elucidation, Process and Analytical Chemistry, Merck & Co., Inc., Boston, MA 02115, United States., Sondey C; Quantitative Biosciences, Merck & Co., Inc., Boston, MA 02115, United States., Mansueto MS; Quantitative Biosciences, Merck & Co., Inc., Boston, MA 02115, United States., Altman MD; Computational and Structural Chemistry, Merck & Co., Inc., Boston, MA 02115, United States., Machacek MR; Discovery Chemistry, Merck & Co., Inc., Boston, MA 02115, United States.
Publikováno v:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2022 Jul 15; Vol. 66, pp. 116820. Date of Electronic Publication: 2022 May 14.
Autor:
Keylor MH; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Gulati A; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Kattar SD; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Johnson RE; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Chau RW; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Margrey KA; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Ardolino MJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Zarate C; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Poremba KE; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Simov V; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Morriello GJ; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States., Acton JJ; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States., Pio B; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States., Yan X; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Palte RL; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., McMinn SE; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Nogle L; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Lesburg CA; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Adpressa D; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Lin S; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States., Neelamkavil S; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States., Liu P; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Su J; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States., Hegde LG; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Woodhouse JD; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Faltus R; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Xiong T; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Ciaccio PJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Piesvaux J; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Otte KM; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Wood HB; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States., Kennedy ME; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Bennett DJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., DiMauro EF; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Fell MJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Fuller PH; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2022 Jan 13; Vol. 65 (1), pp. 838-856. Date of Electronic Publication: 2021 Dec 30.
Autor:
Palte RL; Department of Discovery Chemistry, Merck & Co., Inc., Boston, MA, USA. rachel.kubiak@merck.com., Juan V; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Gomez-Llorente Y; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ, USA., Bailly MA; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Chakravarthy K; Department of Discovery Biology, Merck & Co., Inc., Boston, MA, USA.; Ipsen Bioscience Inc., Cambridge, MA, USA., Chen X; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ, USA., Cipriano D; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Fayad GN; Department of Preclinical Development, Merck & Co., Inc., Boston, MA, USA., Fayadat-Dilman L; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Gathiaka S; Department of Discovery Chemistry, Merck & Co., Inc., Boston, MA, USA., Greb H; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA.; Synthekine Inc., Menlo Park, CA, USA., Hall B; Department of Discovery Biologics, Merck & Co., Inc., Boston, MA, USA., Handa M; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Hsieh M; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Kofman E; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Lin H; Department of Discovery Biologics, Merck & Co., Inc., Boston, MA, USA., Miller JR; Department of Discovery Biology, Merck & Co., Inc., Boston, MA, USA., Nguyen N; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., O'Neil J; Department of Discovery Oncology, Merck & Co., Inc., Boston, MA, USA.; Xilio Therapeutics, Waltham, MA, USA., Shaheen H; Department of Discovery Biologics, Merck & Co., Inc., Boston, MA, USA.; Pandion Therapeutics, Cambridge, MA, USA., Sterner E; Department of Discovery Biologics, Merck & Co., Inc., Boston, MA, USA., Strickland C; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ, USA., Sun A; Department of Discovery Biologics, Merck & Co., Inc., Boston, MA, USA., Taremi S; Department of Discovery Biologics, Merck & Co., Inc., Boston, MA, USA., Scapin G; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ, USA.; NanoImaging Services, Woburn, MA, USA.
Publikováno v:
Communications biology [Commun Biol] 2021 Nov 15; Vol. 4 (1), pp. 1310. Date of Electronic Publication: 2021 Nov 15.
Autor:
Li D; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Zhang H; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Lyons TW; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Lu M; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Achab A; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Pu Q; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Childers M; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Mitcheltree MJ; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Wang J; IDSU, WuXi AppTec Co., Ltd., Shanghai 200131, China., Martinot TA; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., McMinn SE; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Sloman DL; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Palani A; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Beard A; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Nogle L; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Gathiaka S; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Saurí J; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Kim HY; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Adpressa D; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Spacciapoli P; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Miller JR; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Palte RL; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Lesburg CA; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Cumming J; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Fischer C; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2021 Oct 13; Vol. 12 (11), pp. 1678-1688. Date of Electronic Publication: 2021 Oct 13 (Print Publication: 2021).
Autor:
Palte RL; Department of Discovery Chemistry, Merck & Co., Inc., Boston, MA, USA. rachel.kubiak@merck.com., Juan V; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Gomez-Llorente Y; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ, USA., Bailly MA; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Chakravarthy K; Department of Discovery Biology, Merck & Co., Inc., Boston, MA, USA.; Ipsen Bioscience Inc., Cambridge, MA, USA., Chen X; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ, USA., Cipriano D; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Fayad GN; Department of Preclinical Development, Merck & Co., Inc., Boston, MA, USA., Fayadat-Dilman L; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Gathiaka S; Department of Discovery Chemistry, Merck & Co., Inc., Boston, MA, USA., Greb H; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA.; Synthekine Inc., Menlo Park, CA, USA., Hall B; Department of Discovery Biologics, Merck & Co., Inc., Boston, MA, USA., Handa M; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Hsieh M; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Kofman E; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., Lin H; Department of Discovery Biologics, Merck & Co., Inc., Boston, MA, USA., Miller JR; Department of Discovery Biology, Merck & Co., Inc., Boston, MA, USA., Nguyen N; Department of Discovery Biologics, Merck & Co., Inc., South San Francisco, CA, USA., O'Neil J; Department of Discovery Oncology, Merck & Co., Inc., Boston, MA, USA.; Xilio Therapeutics, Waltham, MA, USA., Shaheen H; Department of Discovery Biologics, Merck & Co., Inc., Boston, MA, USA.; Pandion Therapeutics, Cambridge, MA, USA., Sterner E; Department of Discovery Biologics, Merck & Co., Inc., Boston, MA, USA., Strickland C; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ, USA., Sun A; Department of Discovery Biologics, Merck & Co., Inc., Boston, MA, USA., Taremi S; Department of Discovery Biologics, Merck & Co., Inc., Boston, MA, USA., Scapin G; Department of Discovery Chemistry, Merck & Co., Inc., Kenilworth, NJ, USA.; NanoImaging Services, Woburn, MA, USA.
Publikováno v:
Communications biology [Commun Biol] 2021 Jul 29; Vol. 4 (1), pp. 927. Date of Electronic Publication: 2021 Jul 29.
Autor:
Lu M; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Zhang H; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Li D; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Childers M; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Pu Q; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Palte RL; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Gathiaka S; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Lyons TW; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Palani A; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Fan PW; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Spacciapoli P; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Miller JR; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Cho H; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Cheng M; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Chakravarthy K; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., O'Neil J; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Eangoor P; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Beard A; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Kim HY; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Saurí J; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Gunaydin H; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Sloman DL; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Siliphaivanh P; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Cumming J; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Fischer C; Discovery Chemistry, Computational and Structural Chemistry, Quantitative Biosciences, Discovery Process Chemistry, Discovery Oncology, Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, and Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2021 Jul 16; Vol. 12 (9), pp. 1380-1388. Date of Electronic Publication: 2021 Jul 16 (Print Publication: 2021).