Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Paloma Gil-Bernabe"'
Autor:
Atsushi Yasukawa, Koa Hosoki, Masaaki Toda, Yasushi Miyake, Yuki Matsushima, Takahiro Matsumoto, Daniel Boveda-Ruiz, Paloma Gil-Bernabe, Mizuho Nagao, Mayumi Sugimoto, Yukiko Hiraguchi, Reiko Tokuda, Masahiro Naito, Takehiro Takagi, Corina N D'Alessandro-Gabazza, Shigeru Suga, Tetsu Kobayashi, Takao Fujisawa, Osamu Taguchi, Esteban C Gabazza
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64281 (2013)
Eosinophilic inflammation and remodeling of the airways including subepithelial fibrosis and myofibroblast hyperplasia are characteristic pathological findings of bronchial asthma. Epithelial to mesenchymal transition (EMT) plays a critical role in a
Externí odkaz:
https://doaj.org/article/624fd18eef824ff3a3d570e05a942221
Autor:
Tomohiro Hamasaki, Hiroshi Suzuki, Hisao Shirohzu, Takahiro Matsumoto, Corina N D'Alessandro-Gabazza, Paloma Gil-Bernabe, Daniel Boveda-Ruiz, Masahiro Naito, Tetsu Kobayashi, Masaaki Toda, Takayuki Mizutani, Osamu Taguchi, John Morser, Yutaka Eguchi, Masahiko Kuroda, Takahiro Ochiya, Hirotake Hayashi, Esteban C Gabazza, Tadaaki Ohgi
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42655 (2012)
RNA interference (RNAi) is being widely used in functional gene research and is an important tool for drug discovery. However, canonical double-stranded short interfering RNAs are unstable and induce undesirable adverse effects, and thus there is no
Externí odkaz:
https://doaj.org/article/82716a38560e48259e74f1950b23ae7a
Autor:
Josephine A. Hinneh, Isaac Cann, John Morser, Iwasa Motoh, Esteban C. Gabazza, Paloma Gil-Bernabe, Ziaurahman Roeen, Taro Yasuma, Corina N. D’Alessandro-Gabazza, Kota Nishihama, Yutaka Yano, Masaaki Toda, Tetsu Kobayashi, Rumi Mifuji-Moroka, Yoshiyuki Takei
Publikováno v:
Diabetes. 65:1940-1951
Protein S is an anticoagulant factor that also regulates inflammation and cell apoptosis. The effect of protein S on diabetes and its complications is unknown. This study compared the development of diabetes between wild-type and transgenic mice over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4562c2380d155c89eebff4bf5a82f007
https://doi.org/10.2337/db15-1404
https://doi.org/10.2337/db15-1404
Autor:
Masaaki Toda, Takahiro Matsumoto, Tetsu Kobayashi, Yuki Matsushima, John Morser, Paloma Gil-Bernabe, Masahiro Naito, Ayshwarya-Lakshmi Chelakkot-Govindalayathil, Osamu Hataji, Osamu Taguchi, Daniel Boveda-Ruiz, Takehiro Takagi, Atsushi Yasukawa, Yoshiyuki Takei, Corina N. D'Alessandro-Gabazza, Esteban C. Gabazza
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 49:646-653
Acute lung injury (ALI) is a devastating disease with an overall mortality rate of 30 to 40%. The coagulation/fibrinolysis system is implicated in the pathogenesis of ALI. Thrombin-activatable fibronolysis inhibitor (TAFI) is an important component o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c3c67d57580a14e32ffbcbd7aa72e3
https://doi.org/10.1165/rcmb.2012-0454oc
https://doi.org/10.1165/rcmb.2012-0454oc
Autor:
Tetsu Kobayashi, Atsushi Yasukawa, Takahiro Matsumoto, Daniel Boveda-Ruiz, Takehiro Takagi, Yuki Matsushima, Corina N. D'Alessandro-Gabazza, Ayshwarya-Lakshmi Chelakkot-Govindalayathil, John Morser, Paloma Gil-Bernabe, Esteban C. Gabazza, Yasushi Miyake, Osamu Taguchi, Masahiro Naito, Masaaki Toda
Publikováno v:
Immunobiology. 218:245-254
Regulatory T cells (Tregs) are a specific subset of T lymphocytes that regulate the function of other subsets of lymphocytes. Contradictory results have been reported regarding the role of Tregs in lung fibrosis. We wished to clarify the role of Treg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ea8eb9304f76105e43c10fb2c1a879
https://doi.org/10.1016/j.imbio.2012.05.020
https://doi.org/10.1016/j.imbio.2012.05.020
Autor:
Peter D. Wagner, Masaaki Toda, Tetsu Kobayashi, Ayako Fukuda, Yutaka Yano, Esteban C. Gabazza, Takehiro Takagi, Osamu Taguchi, Stephen I. Rennard, Tetsuya Hasegawa, John Morser, Paloma Gil-Bernabe, Hidekazu Toyobuku, Yasushi Miyake, Corina N. D’Alessandro-Gabazza, Yoshiyuki Takei, Daniel Boveda-Ruiz, Noboru Suzuki, Hiromitsu Saito, Atsushi Yasukawa, Yoshikazu Matsuda
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 46:397-406
Idiopathic pulmonary fibrosis is a chronic devastating disease of unknown etiology. No therapy is currently available. A growing body of evidence supports the role of transforming growth factor (TGF)-β1 as the major player in the pathogenesis of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45ca99abf2f039b579e40f4d32fe389
https://doi.org/10.1165/rcmb.2011-0158oc
https://doi.org/10.1165/rcmb.2011-0158oc
Autor:
John Morser, Yasushi Miyake, Corina N. D’Alessandro-Gabazza, Paloma Gil Bernabe, Takehiro Takagi, Yoshiyuki Takei, Seiichi Munesue, Shinya Aoki, Esteban C. Gabazza, Daniel Boveda Ruiz, Fumiko Chiba, Koji Suzuki, Yutaka Yano, Osamu Taguchi, Yasuhiko Yamamoto, Edward M. Conway, Hiroshi Yamamoto, Masaaki Toda, Tetsu Kobayashi
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 183:31-42
bronchial asthma is caused by inappropriate acquired immune responses to environmental allergens. It is a major health problem, with a prevalence that is rapidly increasing. Curative therapy is not currently available.to test the hypothesis that thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d110c200631e0b25a7d0b3f0ff9cd69
https://doi.org/10.1164/rccm.201001-0107oc
https://doi.org/10.1164/rccm.201001-0107oc
Autor:
Tetsuya Beppu, T. Murata, John Morser, Paloma Gil-Bernabe, Yasushi Miyake, Mariko Murata, Masaaki Toda, Yutaka Yano, Yoshikazu Matsuda, Esteban C. Gabazza, Yoshiyuki Takei, Katsuya Shiraki, Corina N. D’Alessandro-Gabazza, Daniel Boveda-Ruiz
Publikováno v:
Journal of Thrombosis and Haemostasis. 8:2514-2522
Summary. Background: Activation of the complement system has been implicated in tumor growth. The antifibrinolytic protein, activated thrombin-activatable fibrinolysis inhibitor (TAFIa), can modulate the activation of the complement system by inactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd051cb5f6487e87c28bad859e07e2b
https://doi.org/10.1111/j.1538-7836.2010.04023.x
https://doi.org/10.1111/j.1538-7836.2010.04023.x
Autor:
Yutaka Yano, Osamu Taguchi, Yasushi Miyake, Liqiang Qin, V. T. San Martin Montenegro, Yoshiyuki Takei, A. Y. Ramirez Marmol, Masaaki Toda, Esteban C. Gabazza, Corina N. D’Alessandro-Gabazza, S. Aoki, John Morser, Paloma Gil-Bernabe, Daniel Boveda-Ruiz, Takehiro Takagi
Publikováno v:
Journal of Thrombosis and Haemostasis. 8:808-816
Summary. Background: The fibrinolytic system has been implicated in the pathogenesis of pulmonary hypertension (PH). Thrombin-activatable fibrinolysis inhibitor (TAFI) inhibits fibrinolysis and therefore its absence would be expected to increase fibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d52537e201329f2ee836da91d593ff
https://doi.org/10.1111/j.1538-7836.2010.03751.x
https://doi.org/10.1111/j.1538-7836.2010.03751.x
Autor:
Ziaurahman Roeen, Taro Yasuma, Esteban C. Gabazza, Paloma Gil-Bernabe, Yoshikazu Matsuda, Ayshwarya-Lakshmi Chelakkot-Govindalayathil, Yoshiyuki Takei, Motoh Iwasa, Corina N. D'Alessandro-Gabazza, Masaaki Toda, Rumi Mifuji-Moroka, Yutaka Yano
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 13(1)
Summary Background Alcohol consumption is a major cause of liver injury but the mechanisms are not completely understood. Protein S (PS) is an anticoagulant glycoprotein with multiple functions. The role of PS in liver injury is unknown. Objectives T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee43e262810605f29c486b24e620e8dc
https://pubmed.ncbi.nlm.nih.gov/25399514
https://pubmed.ncbi.nlm.nih.gov/25399514