Correction: Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain.

Autor: The Quyen Nguyen, Mélanie Chenon, Fernando Vilela, Christophe Velours, Magali Aumont-Nicaise, Jessica Andreani, Paloma F Varela, Paola Llinas, Julie Ménétrey

Publikováno v: PLoS ONE, Vol 13, Iss 5, p e0197193 (2018)

[This corrects the article DOI: 10.1371/journal.pone.0186354.].

Externí odkaz: https://doaj.org/article/f2e5b460a92a44a083ccb24a0e9bc7e6

Structural snapshots of the kinesin‐2 OSM‐3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism

Autor: Paloma F. Varela, Mélanie Chenon, Christophe Velours, Kristen J. Verhey, Julie Ménétrey, Benoît Gigant

Publikováno v: FEBS Open Bio, Vol 11, Iss 3, Pp 564-577 (2021)

Motile kinesins are motor proteins that translocate along microtubules as they hydrolyze ATP. They share a conserved motor domain which harbors both ATPase and microtubule‐binding activities. An ATP hydrolysis mechanism involving two water molecule

Externí odkaz: https://doaj.org/article/11baac956d21439289aea43ce1bac83d

Macromolecular interactions in vitro, comparing classical and novel approaches

Autor: Jean-Baptiste Charbonnier, Christophe Quétard, Pierre Soule, Paloma F. Varela, Guillaume Bec, Adrián Velázquez-Campoy, Christine Ebel, Stephan Uebel, Patrick England, Magali Aumont-Nicaise, David Stroebel, Alain Roussel, Christophe Velours

Publikováno v: European Biophysics Journal
European Biophysics Journal, Springer Verlag (Germany), 2021, 50, pp.313-330. ⟨10.1007/s00249-021-01517-5⟩
European Biophysics Journal, 2021, 50, pp.313-330. ⟨10.1007/s00249-021-01517-5⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname

18 pags., 4 figs. -- This article has been updated, a correction to this article was published on 27 April 2021
Biophysical quantification of protein interactions is central to unveil the molecular mechanisms of cellular processes. Researchers c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc11bcc7f6e9550ab8b8f56d6283fd82
http://hdl.handle.net/10261/253612

Author Correction: A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment

Autor: Yann Herault, Gwenaëlle Le Roux, Amie K. Lund, Serena Pavoni, Laurent Meijer, Anne-Cécile Guyot, Narciso Costa, Aloïse Mabondzo, Clémence Disdier, Nassima Oumata, Paloma F. Varela, Charlotte Leuxe, Jean-Baptiste Charbonnier, Emile Andriambeloson, Hervé Galons, Arnaud Duchon, Stéphanie Wagner

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Scientific Reports

Neurodegenerative diseases, including Alzheimer's and Parkinson's disease, are characterized by increased protein aggregation in the brain, progressive neuronal loss, increased inflammation, and neurogenesis impairment. We analyzed the effects of a n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d3737fc65739d61cd3be385696bf5e
https://doi.org/10.1038/s41598-020-67127-x

MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus

Autor: Jacqueline Cherfils, Christian Galicia, Paloma F. Varela, Wenhua Zhang, Stefano Trapani, Jorge Navaza, Sébastien Lhospice, Tâm Mignot, Julien Herrou

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.5300. ⟨10.1038/s41467-019-13274-3⟩
'Nature Communications ', vol: 10, pages: 5300-1-5300-12 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications, 2019, 10 (1), pp.5300. ⟨10.1038/s41467-019-13274-3⟩
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-13274-3⟩

In Myxococcus xanthus, directed movement is controlled by pole-to-pole oscillations of the small GTPase MglA and its GAP MglB. Direction reversals require that MglA is inactivated by MglB, yet paradoxically MglA and MglB are located at opposite poles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f2e6ad5fb828d02c584dc6201f3f23
https://hal-amu.archives-ouvertes.fr/hal-02423612/document