Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Paloma A. Harcha"'
Autor:
Sebastian Urquiza-Zurich, Victor Antonio Garcia-Angulo, Paula Burdisso, M. Fernanda Palominos, Lucia Fernandez-Hubeid, Paloma A. Harcha, Juan P. Castillo, Andrea Calixto
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Bacterivore nematodes are the most abundant animals in the biosphere, largely contributing to global biogeochemistry. Thus, the effects of environmental microbes on the nematodes’ life-history traits are likely to contribute to the general
Externí odkaz:
https://doaj.org/article/7cdb978dfa9e415197310e647cb99621
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The role of Pannexin (PANX) channels during collective and single cell migration is increasingly recognized. Amongst many functions that are relevant to cell migration, here we focus on the role of PANX-mediated adenine nucleotide release and associa
Externí odkaz:
https://doaj.org/article/c3b5a6c42dc24bda81c8146ad3925f8f
Autor:
Paloma A. Harcha, Ximena López, Pablo J. Sáez, Paola Fernández, Iván Barría, Agustín D. Martínez, Juan C. Sáez
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Mast cells (MCs) release pro-inflammatory mediators through a process called degranulation response. The latter may be induced by several conditions, including antigen recognition through immunoglobulin E (IgE) or “cross-linking,” classically ass
Externí odkaz:
https://doaj.org/article/6913c62c86054f8a89dfa20dd193aa8e
Autor:
Jorge González-Casanova, Oliver Schmachtenberg, Agustín D. Martínez, Helmuth A. Sanchez, Paloma A. Harcha, Diana Rojas-Gomez
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3194 (2021)
Diabetic retinopathy (DR) is one of the main causes of vision loss in the working age population. It is characterized by a progressive deterioration of the retinal microvasculature, caused by long-term metabolic alterations inherent to diabetes, lead
Externí odkaz:
https://doaj.org/article/70c0517f99cf4a8caa07097f6431a9f2
Autor:
Paloma A. Harcha, Polett Garcés, Cristian Arredondo, Germán Fernández, Juan C. Sáez, Brigitte van Zundert
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1924 (2021)
Considered relevant during allergy responses, numerous observations have also identified mast cells (MCs) as critical effectors during the progression and modulation of several neuroinflammatory conditions, including Alzheimer’s disease (AD) and am
Externí odkaz:
https://doaj.org/article/db0ee0c1d9f5429a88c05aa0622bdee6
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
In the central nervous system (CNS), mastocytes and glial cells (microglia, astrocytes and oligodendrocytes) function as sensors of neuroinflammatory conditions, responding to stress triggers or becoming sensitized to subsequent proinflammatory chall
Externí odkaz:
https://doaj.org/article/5ca95e8987e8429684c68751188a7d28
Autor:
Pablo J. Sáez, Kenji F. Shoji, Mauricio A. Retamal, Paloma A. Harcha, Gigliola Ramírez, Jean X. Jiang, Rommy von Bernhardi, Juan C. Sáez
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Microglia are the immune cells in the central nervous system. After injury microglia release bioactive molecules, including cytokines and ATP, which modify the functional state of hemichannels (HCs) and gap junction channels (GJCs), affecting the int
Externí odkaz:
https://doaj.org/article/f24d124a393144398c4f87e90b98ddeb
Autor:
Juan C. Sáez, Germán Fernández, Paloma A. Harcha, Brigitte van Zundert, Cristian Arredondo, Polett Garcés
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1924, p 1924 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Considered relevant during allergy responses, numerous observations have also identified mast cells (MCs) as critical effectors during the progression and modulation of several neuroinflammatory conditions, including Alzheimer’s disease (AD) and am
Publikováno v:
Experimental eye research. 190
The common degu (Octodon degus) is an emerging model in biomedical science research due to its longevity and propensity to develop human-like conditions. However, there is a lack of standardized techniques for this non-traditional laboratory animal.
Autor:
Pablo J, Sáez, Pablo, Vargas, Kenji F, Shoji, Paloma A, Harcha, Ana-María, Lennon-Duménil, Juan C, Sáez
Publikováno v:
Science signaling. 10(506)
Upon its release from injured cells, such as infected, transformed, inflamed, or necrotic cells, extracellular adenosine-5'-triphosphate (ATP) acts as a danger signal that recruits phagocytes, such as neutrophils, macrophages, and dendritic cells (DC