Zobrazeno 1 - 10
of 390
pro vyhledávání: '"Palmer AA"'
Autor:
Sanchez-Roige, S, Palmer, AA, Fontanillas, P, Elson, SL, 23andMe Research Team, Substance Use Disorder Working Group of the Psychiatric Genomics Consortium, Adams, MJ, Howard, DM, Edenberg, HJ, Davies, G, Crist, RC, Deary, IJ, McIntosh, AM, Clarke, T-K
Publikováno v:
Sanchez-Roige, S; Palmer, AA; Fontanillas, P; Elson, SL; 23andMe Research Team,; Substance Use Disorder Working Group of the Psychiatric Genomics Consortium,; et al.(2018). Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.. The American journal of psychiatry, appiajp201818040369. doi: 10.1176/appi.ajp.2018.18040369. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/498384k1
OBJECTIVE::Alcohol use disorders are common conditions that have enormous social and economic consequences. Genome-wide association analyses were performed to identify genetic variants associated with a proxy measure of alcohol consumption and alcoho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::1c35ef49f603bfcb19ddc3883f1e846c
http://www.escholarship.org/uc/item/498384k1
http://www.escholarship.org/uc/item/498384k1
Publikováno v:
de Guglielmo, G; Conlisk, DE; Barkley-Levenson, AM; Palmer, AA; & George, O. (2018). Inhibition of &ITGlyoxalase&IT &IT1&IT reduces alcohol self-administration in dependent and nondependent rats. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 167, 36-41. doi: 10.1016/j.pbb.2018.03.001. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0mg188hr
Previous studies showed that the glyoxalase 1 (Glo1) gene modulates anxiety-like behavior, seizure susceptibility, depression-like behavior, and alcohol drinking in the drinking-in-the-dark paradigm in nondependent mice. Administration of the small-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::8ed8df91f8c0d2c1c58a05e918f5a37c
http://www.escholarship.org/uc/item/0mg188hr
http://www.escholarship.org/uc/item/0mg188hr
Autor:
McMurray, KMJ, Ramaker, MJ, Barkley-Levenson, AM, Sidhu, PS, Elkin, PK, Reddy, MK, Guthrie, ML, Cook, JM, Rawal, VH, Arnold, LA, Dulawa, SC, Palmer, AA
Publikováno v:
Molecular psychiatry, vol 23, iss 2
McMurray, KMJ; Ramaker, MJ; Barkley-Levenson, AM; Sidhu, PS; Elkin, PK; Reddy, MK; et al.(2018). Identification of a novel, fast-acting GABAergic antidepressant. MOLECULAR PSYCHIATRY, 23(2), 384-391. doi: 10.1038/mp.2017.14. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9x4284kb
McMurray, KMJ; Ramaker, MJ; Barkley-Levenson, AM; Sidhu, PS; Elkin, PK; Reddy, MK; et al.(2018). Identification of a novel, fast-acting GABAergic antidepressant. MOLECULAR PSYCHIATRY, 23(2), 384-391. doi: 10.1038/mp.2017.14. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9x4284kb
Current pharmacotherapies for depression exhibit slow onset, side effects and limited efficacy. Therefore, identification of novel fast-onset antidepressants is desirable. GLO1 is a ubiquitous cellular enzyme responsible for the detoxification of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::01d7ea718980a4d27ad304f6b3b33c99
https://escholarship.org/uc/item/9x4284kb
https://escholarship.org/uc/item/9x4284kb
Autor:
Sanchez-Roige, S, Fontanillas, P, Elson, SL, Pandit, A, Schmidt, EM, Foerster, JR, Abecasis, GR, Gray, JC, De Wit, H, Davis, LK, MacKillop, J, Palmer, AA
Publikováno v:
Sanchez-Roige, S; Fontanillas, P; Elson, SL; Pandit, A; Schmidt, EM; Foerster, JR; et al.(2018). Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry. Nature Neuroscience, 21(1), 16-20. doi: 10.1038/s41593-017-0032-x. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/7vj1h8df
© 2017 The Author(s). Delay discounting (DD), the tendency to discount the value of delayed versus current rewards, is elevated in a constellation of diseases and behavioral conditions. We performed a genome-wide association study of DD using 23,127
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::8068c98f2431e66e3969bccd0b17adaa
http://www.escholarship.org/uc/item/7vj1h8df
http://www.escholarship.org/uc/item/7vj1h8df
Autor:
Sanchez-Roige, S, Fontanillas, P, Elson, SL, 23andMe Research Team, Gray, JC, de Wit, H, Davis, LK, MacKillop, J, Palmer, AA
Publikováno v:
Sanchez-Roige, S; Fontanillas, P; Elson, SL; 23andMe Research Team,; Gray, JC; de Wit, H; et al.(2017). Genome-wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry.. Addiction biology. doi: 10.1111/adb.12574. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/6cp6227f
Genetic factors contribute to the risk for developing alcohol use disorder (AUD). In collaboration with the genetics company 23andMe, Inc., we performed a genome-wide association study of the alcohol use disorder identification test (AUDIT), an instr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::d78d50feff606d04c11b3254bf1ddf58
http://www.escholarship.org/uc/item/6cp6227f
http://www.escholarship.org/uc/item/6cp6227f
Autor:
Holl, K, He, H, Wedemeyer, M, Clopton, L, Wert, S, Meckes, JK, Cheng, R, Kastner, A, Palmer, AA, Redei, EE, Solberg Woods, LC
Publikováno v:
Holl, K; He, H; Wedemeyer, M; Clopton, L; Wert, S; Meckes, JK; et al.(2018). Heterogeneous stock rats: a model to study the genetics of despair-like behavior in adolescence. Genes, Brain and Behavior, 17(2), 139-148. doi: 10.1111/gbb.12410. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/61w4j51r
Genes, brain, and behavior, vol 17, iss 2
Genes, brain, and behavior, vol 17, iss 2
© 2017 John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society Major depressive disorder (MDD) is a complex illness caused by both genetic and environmental factors. Antidepressant resistance also has a genetic component. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bd82a96d4874acefe8113982c03db70a
https://europepmc.org/articles/PMC5836722/
https://europepmc.org/articles/PMC5836722/
Autor:
King, CP, Militello, L, Hart, A, St Pierre, CL, Leung, E, Versaggi, CL, Roberson, N, Catlin, J, Palmer, AA, Richards, JB, Meyer, PJ
Publikováno v:
Genes, brain, and behavior, vol 16, iss 7
King, CP; Militello, L; Hart, A; St Pierre, CL; Leung, E; Versaggi, CL; et al.(2017). Cdh13 and AdipoQ gene knockout alter instrumental and Pavlovian drug conditioning. GENES BRAIN AND BEHAVIOR, 16(7), 686-698. doi: 10.1111/gbb.12382. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/4qv053m7
King, CP; Militello, L; Hart, A; St Pierre, CL; Leung, E; Versaggi, CL; et al.(2017). Cdh13 and AdipoQ gene knockout alter instrumental and Pavlovian drug conditioning. GENES BRAIN AND BEHAVIOR, 16(7), 686-698. doi: 10.1111/gbb.12382. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/4qv053m7
Genome-wide association studies in humans have suggested that variants of the cadherin-13 (CDH13) gene are associated with substance use disorder, subjective response to amphetamine, and attention deficit hyperactivity disorder. To examine the role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0d6033d6a4a96aea0598de893c5baa6f
https://escholarship.org/uc/item/4qv053m7
https://escholarship.org/uc/item/4qv053m7
Publikováno v:
Gao, J; Davis, LK; Hart, AB; Sanchez-Roige, S; Han, L; Cacioppo, JT; et al.(2017). Genome-Wide Association Study of Loneliness Demonstrates a Role for Common Variation. Neuropsychopharmacology, 42(4), 811-821. doi: 10.1038/npp.2016.197. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9751w1kb
© 2017 American College of Neuropsychopharmacology. All right reserved. Loneliness is a complex biological trait that has been associated with numerous negative health outcomes. The measurement and environmental determinants of loneliness are well u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::338fc1ad2e1ce70b2e3a289e063aa492
http://www.escholarship.org/uc/item/9751w1kb
http://www.escholarship.org/uc/item/9751w1kb
Publikováno v:
Journal of the experimental analysis of behavior, vol 106, iss 2
Gray, JC; Amlung, MT; Palmer, AA; & MacKillop, J. (2016). Syntax for calculation of discounting indices from the monetary choice questionnaire and probability discounting questionnaire. JOURNAL OF THE EXPERIMENTAL ANALYSIS OF BEHAVIOR, 106(2), 156-163. doi: 10.1002/jeab.221. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/3mp088n8
Gray, JC; Amlung, MT; Palmer, AA; & MacKillop, J. (2016). Syntax for calculation of discounting indices from the monetary choice questionnaire and probability discounting questionnaire. JOURNAL OF THE EXPERIMENTAL ANALYSIS OF BEHAVIOR, 106(2), 156-163. doi: 10.1002/jeab.221. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/3mp088n8
The 27-item Monetary Choice Questionnaire (MCQ; Kirby, Petry, & Bickel, 1999) and 30-item Probability Discounting Questionnaire (PDQ; Madden, Petry, & Johnson, 2009) are widely used, validated measures of preferences for immediate versus delayed rewa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::12dbc3c76cc4620505fb3efa130cb264
https://escholarship.org/uc/item/3mp088n8
https://escholarship.org/uc/item/3mp088n8
Autor:
Parker, CC, Gopalakrishnan, S, Carbonetto, P, Gonzales, NM, Leung, E, Park, YJ, Aryee, E, Davis, J, Blizard, DA, Ackert-Bicknell, CL, Lionikas, A, Pritchard, JK, Palmer, AA
Publikováno v:
Parker, CC; Gopalakrishnan, S; Carbonetto, P; Gonzales, NM; Leung, E; Park, YJ; et al.(2016). Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice. NATURE GENETICS, 48(8), 919-+. doi: 10.1038/ng.3609. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/03r8k1ct
Although mice are the most widely used mammalian model organism, genetic studies have suffered from limited mapping resolution due to extensive linkage disequilibrium (LD) that is characteristic of crosses among inbred strains. Carworth Farms White (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::4d1710af156ce12ecbe3c3ef3caec977
http://www.escholarship.org/uc/item/03r8k1ct
http://www.escholarship.org/uc/item/03r8k1ct