Re-irradiation for progressive Diffuse Intrinsic Pontine Glioma (DIPG): The Spanish experience

Autor: Elena Panizo-Morgado, Felisa Vazquez-Gómez, Marta Perez-Somarriba, Miriam Pavon-Mengual, Andrés Morales-La Madrid, Blanca Lopez-Ibor, Palma Solano, Blanca Martinez de las Heras, Marta Cortés-Hernández, Miguel García-Ariza, Roberto Carlos Raynero-Mellado, Marta Martinez-Merino, Ana de Lucio Delgado, María Tallón-García, Carmen Garrido-Colino, Irene Ortiz-Gonzalez, Raquel Portugal, María Baro-Fernández, Carmen Gonzalez San-Segundo, Felipe Calvo, Alvaro Lassaletta

Publikováno v: EJC Paediatric Oncology, Vol 4, Iss , Pp 100183- (2024)

Introduction: Diffuse intrinsic pontine glioma (DIPG) is the most common malignant brainstem tumour in children. Despite advances in understanding its biology, current treatments have shown minimal impact on overall survival in this fatal disease. Fo

Externí odkaz: https://doaj.org/article/ce7f149b3aea42b3b217a1539e1170f3

Distinct molecular profile of IRF4-rearranged large B-cell lymphoma

Autor: Colleen Ramsower, Matthew J. Oberley, Julia Salmeron-Villalobos, Marta Garrido-Pontnou, Ayman Gaafar, Constantino Sábado, Montserrat Torrent, Leticia Quintanilla-Martinez, Alfredo Rivas-Delgado, Mara Andrés, Federico Garcia-Bragado, Elaine S. Jaffe, Lisa M. Rimsza, Mariona Suñol, Elias Campo, Anna Mozos, Rafael Fernandez-Delgado, Alanna Maguire, Itziar Salaverria, Carmen Bárcena, Itziar Astigarraga, Blanca Gonzalez-Farre, Olga Balagué, Ivan Dlouhy, Armando López-Guillermo, Maitane Andión, Idoia Martin-Guerrero, Ferran Nadeu, Joan Enric Ramis-Zaldivar, Anna Enjuanes, Pallavi Galera, Palma Solano-Páez, Jaime Verdu-Amoros, Guillem Clot, Soledad Gallego, Veronica Celis, Vanesa Perez, Maria Sagaseta de Ilurdoz, Gustavo Tapia, Daniel Azorín

Publikováno v: Blood
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-IGTP: Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Institut de Recerca Germans Trias i Pujol (IGTP)
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Universidad de Alicante (UA)
BLOOD
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA

Pediatric large B-cell lymphomas (LBCLs) share morphological and phenotypic features with adult types but have better prognosis. The higher frequency of some subtypes such as LBCL with IRF4 rearrangement (LBCL-IRF4) in children suggests that some age

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1f002682c581f28b516e7052a62fba
https://doi.org/10.1182/blood.2019002699

RAS/MAPK Pathway Alteration in Pediatric Low-Grade Glioma Complicated with Ventriculo-Peritoneal Shunt Related Ascites

Autor: Candela Freytes, Palma Solano-Paez, Marta Perez-Somarriba, Eric Bouffet, Nisreen Amayiri, Eduardo Quiroga, Lorena V Baroni, Adriana Fonseca, Alvaro Lassaletta

Introduction: Ventriculo-Peritoneal Shunt (VPS) related ascites is a rare complication of pediatric Low Grade Gliomas (pLGG). Physiopathology of this complication is not fully understood and there is paucity of data regarding the molecular profile of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eccdc889b76a7c3c7b9892e907a20348
https://doi.org/10.21203/rs.3.rs-1011776/v1

Clinical phenotypes and prognostic features of embryonal tumours with multi-layered rosettes: a Rare Brain Tumor Registry study

Autor: Milena La Spina, Roona Sinha, Jason E. Cain, Abhaya V. Kulkarni, Nicolas Gottardo, Young-Shin Ra, Jennifer A. Chan, Bryan K. Li, Naureen Mushtaq, Lindsey Hoffman, Maria Joao Gil da Costa, Nada Jabado, Rajeev Vibhakar, Jordan R. Hansford, Palma Solano-Paez, Andrew W. Walter, Anne Bendel, Lili-Naz Hazrati, Michael A. Grotzer, Scott L. Pomeroy, Cynthia Hawkins, Maryam Fouladi, Nicholas Gerber, Ho Keung Ng, Donna L. Johnston, David S. Ziegler, Helen M. Branson, Alexander G. Weil, Tannu Suwal, Jian Qiang Lu, Gino R. Somers, Anna Maria Buccoliero, Ramya Ramanujachar, Ashley Plant, Eloy Rivas, Vanan Magimairajan, Rong Li, Ben Ho, Sandra Camelo-Piragua, Christelle Dufour, Paula Marrano, Uri Tabori, Alyssa Reddy, Sumihito Nobusawa, Jason Fangusaro, James Loukides, Haci Ahmet Demir, Cinzia Lavarino, Angelica Oviedo, Daniel Catchpoole, Yin Wang, Derek Hanson, Joseph Torkildson, Karen Wright, Mette Jorgensen, Nongnuch Sirachainan, Hideo Nakamura, Laetitia Padovani, Luca Massimi, Annie Huang, Rina Dvir, Nalin Gupta, Amy Smith, Sara Khan, Eric Bouffet, Chien-Jui Cheng, Iqra Mumal, Mariko Sato, Jeffery Rubens, Mei Lu, Peter B. Dirks, Jesse Kresak, David Samuel, James T. Rutka, G. Yancey Gillespie, Suzanne Laughlin, Samina Afzal, Salma Al-Karmi, Kuo-Sheng Wu, Claire M. Mazewski, Eugene Hwang, Roger J. Packer, Jean Michaud, Andrew Dodgshun, James M. Drake, Vicente Santa-Maria, Christine Dahl, Sebastian Perreault, Lucie Lafay-Cousin, Frank van Landeghem, Nirav Thacker, Mary Shago, Michael D. Taylor, Derek S. Tsang, Timothy E. Van Meter, Derek Stephens, Adriana Fonseca, Birgit Ertl-Wagner, Mahjouba Boutarbouch, Vijay Ramaswamy, Joanna J. Phillips, Almeida Gonzalez Cv, Jean M. Mulcahy Levy, Benjamin Ellezam, George M. Ibrahim, Nabil Kabbara, Franck Bourdeaut, Violet Shen, Tarik Tihan, Sridharan Gururangan, Tai-Tong Wong, Michal Zapotocky, Michal Yalon-Oren, Helen Toledano, Amar Gajjar, Ute Bartels, Holly Lindsay, Christopher Dunham, Nicolas André, Laura Amariglio, David Scharnhorst, Reuben Antony, Suradej Hongeng, Andres Morales La Madrid, Sharon Low, Paul Wood, Beverly Wilson, Enrica Tan, Peter A. Downie, Dariusz Adamek, Christopher L. Moertel, Alvaro Lassaletta, Chad Jacobsen, Eric H. Raabe, Sarah Leary, Richard Grundy

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Rare Brain Tumor Registry.
[Background] Embryonal tumours with multi-layered rosettes (ETMRs) are a newly recognised, rare paediatric brain tumour with alterations of the C19MC microRNA locus. Due to varied diagnostic practices and scarce clinic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9365cb3fef6cecb8020e0446caf2a15
https://hdl.handle.net/10453/155971

IMMU-13. Dual CTLA4/ PD-1 blockade improves survival for replication-repair deficient high-grade gliomas failing single agent PD-1 inhibition: An IRRDC study

Autor: Anirban Das, Daniel Morgenstern, Vanessa Bianchi, Sumedha Sudhaman, Melissa Edwards, Lucie Stengs, Valerie Larouche, David Samuel, An Van Damme, David Gass, David Ziegler, Stefan Bielack, Shayna Zelcer, Michal Yalon, Shlomi Constantini, Tomasz Sarosiek, Witold Libionka, Kim Nichols, Rebecca Loret De Mola, Kevin Bielamowicz, Magnus Sabel, Charlotta Frojd, Matthew D Wood, Joana Cristiano Sous Migueis, Chenue Abongwa, Lee Yi Yen, Duncan Stearns, Enrico Opocher, Kanika Bhatia, Santanu Sen, Eduardo Quiroga Cantero, Palma Solano Paez, Bruce Crooks, Vanan Magimairajan, Alyssa Reddy, Jenny Adamski, Gary Mason, Scott Lindhorst, Melyssa Aronson, Birgit Ertl-Wagner, Cynthia Hawkins, Eric Bouffet, Uri Tabori

Publikováno v: Neuro-Oncology. 24:i84-i84

BACKGROUND: High-grade gliomas (HGG) with replication-repair deficiency (RRD) harbour high mutation burden (TMB) and are rapidly fatal following chemo-radiation approaches. Although hypermutation results in objective responses and prolonged survival

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f184ff8b0a3e61734789eb25cff90b75
https://doi.org/10.1093/neuonc/noac079.306