Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity.

Autor: Wright TH; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Bower BJ; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Chalker JM; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Bernardes GJ; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Wiewiora R; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Ng WL; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Raj R; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Faulkner S; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Vallée MR; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Phanumartwiwath A; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Coleman OD; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Thézénas ML; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Headington, Oxford OX3 7FZ, UK., Khan M; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Galan SR; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Lercher L; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Schombs MW; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Gerstberger S; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Palm-Espling ME; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Baldwin AJ; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Kessler BM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Headington, Oxford OX3 7FZ, UK., Claridge TD; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Mohammed S; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Davis BG; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK. ben.davis@chem.ox.ac.uk.

Publikováno v: Science (New York, N.Y.) [Science] 2016 Nov 04; Vol. 354 (6312). Date of Electronic Publication: 2016 Sep 22.

Determinants for simultaneous binding of copper and platinum to human chaperone Atox1: hitchhiking not hijacking.

Autor: Palm-Espling ME; Department of Chemistry, Umeå University, Umeå, Sweden., Andersson CD, Björn E, Linusson A, Wittung-Stafshede P

Publikováno v: PloS one [PLoS One] 2013 Jul 30; Vol. 8 (7), pp. e70473. Date of Electronic Publication: 2013 Jul 30 (Print Publication: 2013).

Reaction of platinum anticancer drugs and drug derivatives with a copper transporting protein, Atox1.

Autor: Palm-Espling ME; Department of Chemistry, Chemical Biological Center, Umeå University, 90187 Umeå, Sweden., Wittung-Stafshede P

Publikováno v: Biochemical pharmacology [Biochem Pharmacol] 2012 Apr 01; Vol. 83 (7), pp. 874-81. Date of Electronic Publication: 2012 Jan 21.