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Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia.

Autor: Wen J; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Trost B; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada., Engchuan W; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada., Halvorsen M; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Pallotto LM; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada., Mitina A; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada., Ancalade N; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Farrell M; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Backstrom I; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada., Guo K; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada., Pellecchia G; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada., Thiruvahindrapuram B; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada., Giusti-Rodriguez P; Department of Psychiatry, University of Florida College of Medicine, Gainesville, FL, 32610, USA., Rosen JD; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Li Y; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA.; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, 27599, USA., Won H; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, 17177, Sweden., Gyllensten U; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, 75185, Sweden., Bassett AS; Clinical Genetics Research Program and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, M6J 1H4, Canada.; The Dalglish Family 22q Clinic for Adults with 22q11.2 Deletion Syndrome, Toronto General Hospital, and Toronto General Hospital Research Institute, University Health Network, Toronto, ON, M5G 2C4, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON, M5S 1A8, Canada., Hultman CM; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, 17177, Sweden., Sullivan PF; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, 17177, Sweden.; Department of Psychiatry, University of North Carolina, Chapel Hill, NC, 27599, USA., Yuen RKC; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada. ryan.yuen@sickkids.ca.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada. ryan.yuen@sickkids.ca., Szatkiewicz JP; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA. jin_szatkiewicz@med.unc.edu.; Department of Psychiatry, University of North Carolina, Chapel Hill, NC, 27599, USA. jin_szatkiewicz@med.unc.edu.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2023 Jan; Vol. 28 (1), pp. 475-482. Date of Electronic Publication: 2022 Nov 16.