Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Palle Jakobsen"'
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:2625-2632
Transport across the intestinal barrier of compounds with low permeability may be facilitated by targeting the human oligopeptide transporter, hPepT1. A flexible synthetic pathway for attaching compounds to dipeptides through ester or amide bonds was
Publikováno v:
The Journal of Organic Chemistry. 66:4214-4219
4-Substituted pyrazolo[4,3-c]quinolines 4a−i and 6a−b were prepared from pyrazole 3 whereas 9-substituted pyrazolo[3,4-c]quinolines 9a−d and 17 were prepared from pyrazole 13 utilizing anionic annelation techniques. 1,4-Dihydrochromeno[4,3-c]py
Publikováno v:
Bioorganic & Medicinal Chemistry. 8:2803-2812
The synthesis of a series of 2-aryl substituted hetero annulated 1,3-oxazin-4-ones and their evaluation as specific inhibitors of the tissue factor (TF)/factor VIIa (FVIIa)-induced pathway of coagulation is reported. Inhibitory activities (IC50 value
Publikováno v:
Bioorganic & Medicinal Chemistry. 8:2095-2103
The synthesis of a series of novel 2-aryl substituted 4H-3,1-benzoxazin-4-ones and their evaluation as specific inhibitors of the Tissue Factor (TF)/Factor VIIa (FVIIa)-induced pathway of coagulation is reported. Inhibitory activities (IC50 values) i
Publikováno v:
Immunology. 93:264-269
To better understand reasons for increased susceptibility to malaria in pregnancy; and the interrelationships between maternal malaria, local immune reactions and the development of the fetus, concentrations of soluble interleukin-10 (IL-10), cytokin
Autor:
Hayder A. Giha, Edward E Zijlstra, Ibrahim M. Elhassan, Trine Staalsø, Ahmed M. Elhassan, Eltahir A G Khalil, Palle Jakobsen, Thor G. Theander
Publikováno v:
Immunology Letters. 60:121-126
The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family of protein antigens are involved in adhesion of P. falciparum infected erythrocytes to the capillary endothelium of the host. Antibodies to variable regions of these proteins, m
Autor:
H. Fujioka, Thor G. Theander, Ib C. Bygbjerg, Masamichi Aikawa, Palle Jakobsen, Riad Bayoumi, Claus Koch, Lars Hviid
Publikováno v:
Immunology Letters. 59:35-42
Monoclonal antibodies (Mab) were raised against haemoglobin (Hb) associated with Plasmodium falciparum protein and used to develop an ELISA, measuring circulating levels of released Hb. This assay was evaluated in different malaria patients in parall
Autor:
Brian Greenwood, Jørgen A. L. Kurtzhals, James B. Jensen, E.M. Riley, S. Morris-Jones, Palle Jakobsen, R. G. Ridley, Riad Bayoumi, Thor G. Theander, Lars Hviid
Publikováno v:
Parasite Immunology. 19:387-393
Plasma IgM and IgG antibody reactivities against the recombinant Plasmodium falciparum protein, Rhoptry Associated Protein-1 (rRAP-1) were measured by ELISA in individuals from Sudan, Indonesia, Kenya and The Gambia living in areas of different malar
Autor:
JA Akida, H.A. Msangeni, Ib C. Bygbjerg, J. Mhina, Anita M. Rønn, Martha M. Lemnge, Peter M. H. Heegaard, Yousif A. Abu-Zeid, R. G. Ridley, A. S. Ruta, Palle Jakobsen, F.M. Salum
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 55:642-646
In the Muheza region of Tanzania, an area with holoendemic malaria, the proportion of responders with IgG enzyme-linked immunosorbent assay reactivities to recombinant rhoptry-associated protein-1 (rRAP-1) as well as IgG reactivities to a repeat regi
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 55:69-75
The profile of filarial-specific immunoglobulin G1 (IgG1), IgG4, and Wuchereria bancrofti-specific circulating antigen (Og4C3) was analyzed in individuals one year of age and older in a community with high endemicity for Bancroftian filariasis. The o