Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pallavi M. Gosavi"'
Autor:
Kevin Chun-Ho Ngan, Samuel M Hoenig, Hui Si Kwok, Nicholas Z Lue, Pallavi M Gosavi, David A Tanner, Emma M Garcia, Ceejay Lee, Brian B Liau
Publikováno v:
eLife, Vol 12 (2023)
Allostery enables dynamic control of protein function. A paradigmatic example is the tightly orchestrated process of DNA methylation maintenance. Despite the fundamental importance of allosteric sites, their identification remains highly challenging.
Externí odkaz:
https://doaj.org/article/77dc5b6fa55344c28ec05a1bf2d5c339
Autor:
Kevin Chun-Ho Ngan, Samuel M Hoenig, Hui Si Kwok, Nicholas Z Lue, Pallavi M Gosavi, David A Tanner, Emma M Garcia, Ceejay Lee, Brian B Liau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5af23885b076db27413b07fe53044042
https://doi.org/10.7554/elife.80640.sa2
https://doi.org/10.7554/elife.80640.sa2
Autor:
Mary Beth B. Monroe, Kelly M. Schultz, Olga V. Makhlynets, Zsofia Lengyel-Zhand, Matthew D. Wehrman, Areetha D'Souza, Alex Sternisha, Liam R. Marshall, Pallavi M. Gosavi, Jennifer H. Yoon, Garrick Centola, Henry T. Beaman
Publikováno v:
ACS Applied Materials & Interfaces. 12:17091-17099
Silver compounds have been used extensively for wound healing because of their antimicrobial properties, but high concentrations of silver are toxic to mammalian cells. We designed a peptide that binds silver and releases only small amounts of this i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cffc8b2a3774191bce25330733394c7
https://doi.org/10.1021/acsami.0c01154
https://doi.org/10.1021/acsami.0c01154
Autor:
Ivan V. Korendovych, Pallavi M. Gosavi
Publikováno v:
Current Opinion in Chemical Biology. 34:103-109
Spectroscopic studies of small proteins and peptides, especially those requiring fine spatial and/or temporal resolution, demand synthetic probes that confer the minimal possible steric and functional change on the native properties. Here we review t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::550c7ceb426b0c2e3268c6651dba670a
https://doi.org/10.1016/j.cbpa.2016.08.010
https://doi.org/10.1016/j.cbpa.2016.08.010
Publikováno v:
Angewandte Chemie International Edition. 55:9017-9020
We have shown that de novo designed peptides self-assemble in the presence of copper to create supramolecular assemblies capable of carrying out the oxidation of dimethoxyphenol in the presence of dioxygen. Formation of the supramolecular assembly, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483c70e860571519d1201a0c1b371f0c
https://doi.org/10.1002/anie.201602480
https://doi.org/10.1002/anie.201602480
Autor:
Joel J. L. Rempillo, Megha Jayachandran, Pallavi M. Gosavi, Oleksii Zozulia, Olga V. Makhlynets, Ivan V. Korendovych
A computationally designed, allosterically regulated catalyst (CaM M144H) produced by substituting a single residue in calmodulin, a non-enzymatic protein, is capable of efficient and site selective post-translational acylation of lysines in peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b72e83dd402618b2b1d44fd3ca394c
https://europepmc.org/articles/PMC6394838/
https://europepmc.org/articles/PMC6394838/
Autor:
Olga V. Makhlynets, Pallavi M. Gosavi, Tiffany T. Dunston, Ivan V. Korendovych, Yibing Wu, Nico A. J. van Nuland, Jennifer H. Yoon, Alissa B. Olsen, Korrie L. Mack, Olesia V. Moroz, Jaclyn M. McLaughlin, Yurii S. Moroz
Publikováno v:
Journal of the American Chemical Society. 137:14905-14911
Design of a new catalytic function in proteins, apart from its inherent practical value, is important for fundamental understanding of enzymatic activity. Using a computationally inexpensive, minimalistic approach that focuses on introducing a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8203af4f16df199d2c88946c896999
https://doi.org/10.1021/jacs.5b07812
https://doi.org/10.1021/jacs.5b07812
Autor:
Pallavi M. Gosavi, Amy E. Chavis, Joseph E. Reiner, Christopher E. Angevine, Yurii S. Moroz, Gregory A. Caputo, Zachary Ridgway, Angela L. Picciano, Ivan V. Korendovych
Publikováno v:
Biopolymers. 104:384-394
Tryptophan (Trp) is a naturally occurring amino acid, which exhibits fluorescence emission properties that are dependent on the polarity of the local environment around the Trp side chain. However, this sensitivity also complicates interpretation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63276352580bc4e6b0b9a5bfdf55f462
https://doi.org/10.1002/bip.22624
https://doi.org/10.1002/bip.22624
Autor:
William F. DeGrado, Haifan Wu, Tuo Wang, Olga V. Makhlynets, Jan Stöhr, Ivan V. Korendovych, Yibing Wu, Nicholas F. Polizzi, Pallavi M. Gosavi, Myungwoon Lee, Mei Hong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 24
Throughout biology, amyloids are key structures in both functional proteins and the end product of pathologic protein misfolding. Amyloids might also represent an early precursor in the evolution of life because of their small molecular size and thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d62c7d15c4d487fa4d45be63149ea29
https://escholarship.org/uc/item/6ph1k6k8
https://escholarship.org/uc/item/6ph1k6k8
Publikováno v:
Materials Letters. 112:32-35
This study reports in situ crosslinking of electrospun alginate/polyvinyl alcohol nanofibers using citric acid. Porous, interconnected network of nanofibers (mean diameter=250±30 nm) were electrospun from a homogeneous blend of sodium alginate-polyv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d0b26488bc4c69b1f64eb06a7c74ca9
https://doi.org/10.1016/j.matlet.2013.08.100
https://doi.org/10.1016/j.matlet.2013.08.100