Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Pallavi Chandakkar"'
Autor:
Valérie Vingtdeux, Haitian Zhao, Pallavi Chandakkar, Christopher M Acker, Peter Davies, Philippe Marambaud
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 841-849 (2016)
Abstract Strategies aimed at reducing cerebral accumulation of the amyloid-β (Aβ) peptides have therapeutic potential in Alzheimer’s disease (AD). Aβ immunization has proven to be effective at promoting Aβ clearance in animal models, but advers
Externí odkaz:
https://doaj.org/article/84d5ac9f3e794abe8f2434556bbc913a
Autor:
Valérie Vingtdeux, Jessica E Tanis, Pallavi Chandakkar, Haitian Zhao, Ute Dreses-Werringloer, Fabien Campagne, J Kevin Foskett, Philippe Marambaud
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112484 (2014)
CALHM1 is a plasma membrane voltage-gated Ca2+-permeable ion channel that controls amyloid-β (Aβ) metabolism and is potentially involved in the onset of Alzheimer's disease (AD). Recently, Rubio-Moscardo et al. (PLoS One (2013) 8: e74203) reported
Externí odkaz:
https://doaj.org/article/dcc9cf9544d840f3a0ff8b8499002e31
Autor:
Santiago Ruiz, Haitian Zhao, Christine N. Metz, Fabien Campagne, Julien Papoin, Pallavi Chandakkar, Philippe Marambaud, Lionel Blanc, Erica Christen, Prodyot K. Chatterjee
Publikováno v:
Human Molecular Genetics. 26:4786-4798
Hereditary hemorrhagic telangiectasia (HHT) is a highly debilitating and life-threatening genetic vascular disorder arising from endothelial cell (EC) proliferation and hypervascularization, for which no cure exists. Because HHT is caused by loss-of-
Autor:
Matthew Gillen, Ping Wang, Yousef Al-Abed, Fabien Campagne, Mingzhu He, Li Diao, Haitian Zhao, Aya Nomura-Kitabayashi, Lionel Blanc, Hyunwoo Choi, S. Paul Oh, Philippe Marambaud, Prodyot K. Chatterjee, Pallavi Chandakkar, Radhika Patel, Julien Papoin, Santiago Ruiz, Christine N. Metz
Hereditary hemorrhagic telangiectasia (HHT), a genetic bleeding disorder leading to systemic arteriovenous malformations (AVMs), is caused by loss-of-function mutations in the ALK1-ENG-Smad1/5/8 pathway. Evidence suggests that HHT pathogenesis strong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8473fc22e32495742122408da21c5a44
Autor:
Fabien Campagne, Aya Nomura-Kitabayashi, Mingzhu He, Lionel Blanc, Yousef Al-Abed, Santiago Ruiz, Ping Wang, Christine N. Metz, Haitian Zhao, Pallavi Chandakkar, Radhika Patel, Hyunwoo Choi, S. Paul Oh, Philippe Marambaud, Julien Papoin, Li Diao, Prodyot K. Chatterjee, Matthew Gillen
Publikováno v:
J Clin Invest
Hereditary hemorrhagic telangiectasia (HHT), a genetic bleeding disorder leading to systemic arteriovenous malformations (AVMs), is caused by loss-of-function mutations in the ALK1/ENG/Smad1/5/8 pathway. Evidence suggests that HHT pathogenesis strong
Autor:
Philippe Marambaud, Fabien Campagne, Erica Christen, Santiago Ruiz, Christine N. Metz, Pallavi Chandakkar, Lionel Blanc, Prodyot K. Chatterjee, Julien Papoin, Haitian Zhao
Hereditary hemorrhagic telangiectasia (HHT) is a genetic vascular disorder arising from endothelial cell (EC) proliferation and hypervascularization, for which no cure exists. Because HHT is caused by loss-of-function mutations in BMP9-ALK1-Smad1/5/8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e88c6573b00f6179e343ce968b3c90d
https://doi.org/10.1101/137737
https://doi.org/10.1101/137737
Autor:
Santiago Ruiz, Christine N. Metz, Lionel Blanc, Philippe Marambaud, Pallavi Chandakkar, Haitian Zhao, Fabien Campagne, Prodyot K. Chatterjee
Hereditary hemorrhagic telangiectasia (HHT) is a potentially life-threatening genetic vascular disorder caused by loss-of-function mutations in the genes encoding activin receptor-like kinase 1 (ALK1), endoglin, Smad4, and bone morphogenetic protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10c7755e1223c4825d32af06de20443
https://doi.org/10.1101/084889
https://doi.org/10.1101/084889
Autor:
Haitian Zhao, Pallavi Chandakkar, Prodyot K. Chatterjee, Lionel Blanc, Philippe Marambaud, Fabien Campagne, Santiago Ruiz, Christine N. Metz, Julien Papoin
Publikováno v:
Scientific Reports
Hereditary hemorrhagic telangiectasia (HHT) is a potentially life-threatening genetic vascular disorder caused by loss-of-function mutations in the genes encoding activin receptor-like kinase 1 (ALK1), endoglin, Smad4 and bone morphogenetic protein 9
Autor:
Peter Davies, Pallavi Chandakkar, Ute Dreses-Werringloer, Philippe Marambaud, Valérie Vingtdeux, Haitian Zhao
Publikováno v:
Journal of Cell Science. 126:1199-1206
Summary Calcium homeostasis modulator 1 (CALHM1) is a Ca2+ channel controlling neuronal excitability and potentially involved in the pathogenesis of Alzheimer's disease (AD). Although strong evidence indicates that CALHM1 is required for neuronal ele
Autor:
Sebastien Didier, Luc Buée, Manon Domise, Haitian Zhao, Philippe Marambaud, Valérie Vingtdeux, Benoit Viollet, Claudia Marinangeli, Peter Davies, Pallavi Chandakkar
Publikováno v:
Scientific Reports
Neurofibrillary tangles (NFTs) are the pathological hallmark of neurodegenerative diseases commonly known as tauopathies. NFTs result from the intracellular aggregation of abnormally and hyperphosphorylated tau proteins. Tau functions, which include