Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Pallavi Bhattaram"'
Autor:
Archana Kamalakar, Brendan Tobin, Sundus Kaimari, M Hope Robinson, Afra I Toma, Timothy Cha, Samir Chihab, Irica Moriarity, Surabhi Gautam, Pallavi Bhattaram, Shelly Abramowicz, Hicham Drissi, Andres Garcia, Levi Wood, Steven L Goudy
Publikováno v:
eLife, Vol 13 (2024)
Current treatments for congenital and acquired craniofacial (CF) bone abnormalities are limited and costly. Conventional methods involve surgical correction, short-term stabilization, and long-term bone grafting, which may include problematic allogra
Externí odkaz:
https://doaj.org/article/0089cf3ed1324a5a8e384123ccfabe55
Autor:
Sergio Ramirez-Perez, Rushi Vekariya, Surabhi Gautam, Itzel Viridiana Reyes-Perez, Hicham Drissi, Pallavi Bhattaram
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-15 (2023)
Abstract Background Dimerization of the myeloid differentiation primary response 88 protein (MyD88) plays a pivotal role in the exacerbated response to innate immunity-dependent signaling in rheumatoid arthritis (RA). ST2825 is a highly specific inhi
Externí odkaz:
https://doaj.org/article/0c3f45e445064769a1e48daf8b3677c3
Autor:
Nazir M Khan, Martha Elena Diaz-Hernandez, Samir Chihab, Priyanka Priyadarshani, Pallavi Bhattaram, Luke J Mortensen, Rosa M Guzzo, Hicham Drissi
Publikováno v:
eLife, Vol 12 (2023)
Induced pluripotent stem cells (iPSCs) are potential cell sources for regenerative medicine. The iPSCs exhibit a preference for lineage differentiation to the donor cell type indicating the existence of memory of origin. Although the intrinsic effect
Externí odkaz:
https://doaj.org/article/aac6c27662114cf4a8e970f61611ed7d
Autor:
Sergio Ramirez-Perez, Itzel Viridiana Reyes-Perez, Diana Emilia Martinez-Fernandez, Luis Alexis Hernandez-Palma, Pallavi Bhattaram
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105548- (2022)
Summary: Arthritic diseases have attracted enormous scientific interest because of increased worldwide prevalence and represent a significant socioeconomic burden. Osteoarthritis (OA) is the most prevalent form of arthritis. It is a disorder of the d
Externí odkaz:
https://doaj.org/article/741c8dd943a44d559228d6f29595e3a8
Autor:
Kyle Jones, Marco Angelozzi, Umesh Gangishetti, Abdul Haseeb, Charles deCharleroy, Véronique Lefebvre, Pallavi Bhattaram
Publikováno v:
ACR Open Rheumatology, Vol 3, Iss 6, Pp 359-370 (2021)
Objectives Fibroblast‐like synoviocytes (FLS) and articular chondrocytes (AC) derive from a common pool of embryonic precursor cells. They are currently believed to engage in largely distinct differentiation programs to build synovium and articular
Externí odkaz:
https://doaj.org/article/5d600c0a65cb4fc58f69fdb674fb38b8
Autor:
Adrian J. Giovannone, Elena Reales, Pallavi Bhattaram, Sirpi Nackeeran, Adam B. Monahan, Rashid Syed, Thomas Weimbs
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Syntaxins are a family of membrane-anchored SNARE proteins that are essential components required for membrane fusion in eukaryotic intracellular membrane trafficking pathways. Syntaxins contain an N-terminal regulatory domain, termed the Ha
Externí odkaz:
https://doaj.org/article/312ac1bd715e454dbbec8c5acdc7cf54
Autor:
Kyle Jones, Sergio Ramirez-Perez, Sean Niu, Umesh Gangishetti, Hicham Drissi, Pallavi Bhattaram
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
SOX4 belongs to the group C of the SOX transcription factor family. It is a critical mediator of tumor necrosis factor alpha (TNF)-induced transformation of fibroblast-like s-ynoviocytes (FLS) in arthritis. In this study we investigated the genome wi
Externí odkaz:
https://doaj.org/article/22bbb12b68474105954461aa1e883d35
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
MyD88-dependent intracellular signalling cascades and subsequently NF-kappaB-mediated transcription lead to the dynamic inflammatory processes underlying the pathogenesis of rheumatoid arthritis (RA) and related autoimmune diseases. This study aimed
Externí odkaz:
https://doaj.org/article/d8aebd027df54e75ba1173d66b195e92
Publikováno v:
Bio-Protocol, Vol 8, Iss 3 (2018)
The uptake and trafficking of cell surface receptors can be monitored by a technique called ‘antibody-feeding’ which uses an externally applied antibody to label the receptor on the surface of cultured, live cells. Here, we adapt the traditional
Externí odkaz:
https://doaj.org/article/64cdce6d749c4d17b548ce94afde5ff9
Autor:
Bogdan Dumitriu, Pallavi Bhattaram, Peter Dy, Yuanshuai Huang, Nayeem Quayum, Jan Jensen, Véronique Lefebvre
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12088 (2010)
BACKGROUND: Definitive erythropoiesis is a vital process throughout life. Both its basal activity under physiological conditions and its increased activity under anemia-induced stress conditions are highly stimulated by the hormone erythropoietin. Th
Externí odkaz:
https://doaj.org/article/3e235c17c81a4bd384e12769a9b63507