Výsledky vyhledávání - "Pallavi Asthana"

Akademický článek

Artesunate treats obesity in male mice and non-human primates through GDF15/GFRAL signalling axis

Autor: Xuanming Guo, Pallavi Asthana, Lixiang Zhai, Ka Wing Cheng, Susma Gurung, Jiangang Huang, Jiayan Wu, Yijing Zhang, Arun Kumar Mahato, Mart Saarma, Mart Ustav, Hiu Yee Kwan, Aiping Lyu, Kui Ming Chan, Pingyi Xu, Zhao-Xiang Bian, Hoi Leong Xavier Wong

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)

Abstract Obesity, a global health challenge, is a major risk factor for multiple life-threatening diseases, including diabetes, fatty liver, and cancer. There is an ongoing need to identify safe and tolerable therapeutics for obesity management. Here

Externí odkaz: https://doaj.org/article/a29cc025e9664a529d8c924433238848

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Akademický článek

Prediction of Student’s Performance With Learning Coefficients Using Regression Based Machine Learning Models

Autor: Pallavi Asthana, Sumita Mishra, Nishu Gupta, Mohammad Derawi, Anil Kumar

Publikováno v: IEEE Access, Vol 11, Pp 72732-72742 (2023)

Advanced machine learning (ML) methods can predict student’s performance with key features based on academic, behavioral, and demographic data. Significant works have predicted the student’s performance based on the primary and secondary data set

Externí odkaz: https://doaj.org/article/8babf87b0e5c47e1aa66f88ad71d7c23

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Akademický článek

Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)

The role of soluble angiotensin converting enzyme 2 (sACE2) in SARS-CoV-2 infection is not well understood. Here, authors show that membrane type 1 matrix metalloproteinase (MT1-MMP) releases sACE2 to promote SARS-CoV-2 cell entry in vitro and in viv

Externí odkaz: https://doaj.org/article/b805e181bd2d4dafb2de5ce5eb516da8

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Akademický článek

Clinically relevant small-molecule promotes nerve repair and visual function recovery

Autor: Ngan Pan Bennett Au, Gajendra Kumar, Pallavi Asthana, Fuying Gao, Riki Kawaguchi, Raymond Chuen Chung Chang, Kwok Fai So, Yang Hu, Daniel H. Geschwind, Giovanni Coppola, Chi Him Eddie Ma

Publikováno v: npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-16 (2022)

Abstract Adult mammalian injured axons regenerate over short-distance in the peripheral nervous system (PNS) while the axons in the central nervous system (CNS) are unable to regrow after injury. Here, we demonstrated that Lycium barbarum polysacchar

Externí odkaz: https://doaj.org/article/59d7549c2a1b4038917bf05b09f9ef36

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Akademický článek

Cerebellar glutamatergic system impacts spontaneous motor recovery by regulating Gria1 expression

Autor: Pallavi Asthana, Gajendra Kumar, Lukasz M. Milanowski, Ngan Pan Bennett Au, Siu Chung Chan, Jianpan Huang, Hemin Feng, Kin Ming Kwan, Jufang He, Kannie Wai Yan Chan, Zbigniew K. Wszolek, Chi Him Eddie Ma

Publikováno v: npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-19 (2022)

Abstract Peripheral nerve injury (PNI) often results in spontaneous motor recovery; however, how disrupted cerebellar circuitry affects PNI-associated motor recovery is unknown. Here, we demonstrated disrupted cerebellar circuitry and poor motor reco

Externí odkaz: https://doaj.org/article/3b2eeb318d0e4288b3702b110a4ba585

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Akademický článek

Regulation of age-associated insulin resistance by MT1-MMP-mediated cleavage of insulin receptor

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)

Insulin sensitivity declines with age via unclear mechanisms. Here, the authors show that the activity of membrane type 1 matrix metalloproteinase (MT1-MMP) is increased with ageing, leading to cleavage of the insulin receptor, and show that metaboli

Externí odkaz: https://doaj.org/article/32333283ecad4975964575d74c627b97

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A Framework for Computerized Adaptive Assessment based on Trajectory Driven Pedagogy Implemented in an Engineering Course

Autor: Pallavi Asthana, Anil Kumar, Sudeep Tanwar, Sumita Mishra

Publikováno v: International Journal on Recent and Innovation Trends in Computing and Communication. 10:19-30

Engineering education needs to be flexible with the changing technology, and it must blend traditional and new teaching pedagogy for the overall knowledge creation in the students. A survey of prevalent experiential learning methods has shown tremend

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb488285a00efd2f3ace5d1daad836c7
https://doi.org/10.17762/ijritcc.v10i1s.5792

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