Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Pallabi Sil"'
Autor:
Pallabi Sil Paul, Tark Patel, Jae-Young Cho, Allan Yarahmady, Aria Khalili, Valentyna Semenchenko, Holger Wille, Marianna Kulka, Sue-Ann Mok, Satyabrata Kar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Evidence suggests that beta-amyloid (Aβ)-induced phosphorylation/aggregation of tau protein plays a critical role in the degeneration of neurons and development of Alzheimer’s disease (AD), the most common cause of dementia affecting the
Externí odkaz:
https://doaj.org/article/873e2f7dd82d41a68b93515e4db067ac
Autor:
Pallabi Sil Paul, Jae-Young Cho, Qi Wu, Govindarajan Karthivashan, Emily Grabovac, Holger Wille, Mariana Kulka, Satyabrata Kar
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-26 (2022)
Abstract Conversion of β-amyloid (Aβ) peptides from soluble random-coil to aggregated protein enriched with β-sheet-rich intermediates has been suggested to play a role in the degeneration of neurons and development of Alzheimer’s disease (AD) p
Externí odkaz:
https://doaj.org/article/280d20a778fa42f98e881597e1943749
Autor:
Ritobrita Chakraborty, Sandip Dey, Pallabi Sil, Simanta Sarani Paul, Dipita Bhattacharyya, Anirban Bhunia, Jayati Sengupta, Krishnananda Chattopadhyay
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Chakraborty et al. present biophysical and structural insights into fibril-forming oligomers of alpha-synuclein stabilized by heme. They show that heme targets the His50 residue of the oligomers and locks the protein into a different conformation whi
Externí odkaz:
https://doaj.org/article/25742eb9b9d54e619cd7385d8ac904d4
Autor:
Paul, Pallabi Sil1 (AUTHOR), Patel, Tark2 (AUTHOR), Cho, Jae-Young3 (AUTHOR), Yarahmady, Allan2 (AUTHOR), Khalili, Aria3 (AUTHOR), Semenchenko, Valentyna3 (AUTHOR), Wille, Holger2 (AUTHOR), Kulka, Marianna3,4 (AUTHOR), Mok, Sue-Ann2 (AUTHOR), Kar, Satyabrata1,5 (AUTHOR) skar@ualberta.ca
Publikováno v:
Scientific Reports. 1/5/2024, Vol. 14 Issue 1, p1-16. 16p.
Autor:
Paul, Pallabi Sil1 (AUTHOR), Cho, Jae-Young2 (AUTHOR), Wu, Qi1 (AUTHOR), Karthivashan, Govindarajan1 (AUTHOR), Grabovac, Emily2 (AUTHOR), Wille, Holger3 (AUTHOR), Kulka, Marianna2,4 (AUTHOR), Kar, Satyabrata1,5 (AUTHOR) skar@ualberta.ca
Publikováno v:
Journal of Nanobiotechnology. 3/8/2022, Vol. 20 Issue 1, p1-26. 26p.
Autor:
Paul, Pallabi Sil, Cho, Jae-Young, Wu, Qi, Karthivashan, Govindarajan, Grabovac, Emily, Wille, Holger, Kulka, Marianna, Kar, Satyabrata
Additional file 1: Figure S1. ThT kinetic assays showing aggregation of 2.5���20 ��M A��1���42 over a 24 h incubation at 27 ��C (A), 37 ��C (B) and 40 ��C (C). Figure S2. A���C ThT assays showing aggregation kine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f190b33490f707a305a1ff2fdd0ef30
Autor:
Pallabi Sil Paul, Jae-Young Cho, Qi Wu, Govindarajan Karthivashan, Emily Grabovac, Holger Wille, Marianna Kulka, Satyabrata Kar
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-26 (2022)
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-26 (2022)
Conversion of β-amyloid (Aβ) peptides from soluble random-coil to aggregated protein enriched with β-sheet-rich intermediates has been suggested to play a role in the degeneration of neurons and development of Alzheimer’s disease (AD) pathology.
Autor:
Jayati Sengupta, Ritobrita Chakraborty, Simanta Sarani Paul, Sandip Dey, Dipita Bhattacharyya, Krishnananda Chattopadhyay, Anirban Bhunia, Pallabi Sil
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
The fibrillation pathway of alpha-Synuclein, the causative protein of Parkinson’s disease, encompasses transient, heterogeneous oligomeric forms whose structural understanding and link to toxicity are not yet understood. We report that the addition
Publikováno v:
Endocrine Abstracts.
Publikováno v:
Journal of the Endocrine Society
Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting key enzymes of cortisol biosynthesis. In the majority of cases the underlying cause are detrimental mutations in the steroidogenic cytochrome P450 enzyme 21-hy