Recent developments in StemBase: a tool to study gene expression in human and murine stem cells

Autor: Krzyzanowski Paul M, Porter Christopher J, Huska Matthew R, Palidwor Gareth A, Sandie Reatha, Muro Enrique M, Perez-Iratxeta Carolina, Andrade-Navarro Miguel A

Publikováno v: BMC Research Notes, Vol 2, Iss 1, p 39 (2009)

Abstract Background Currently one of the largest online repositories for human and mouse stem cell gene expression data, StemBase was first designed as a simple web-interface to DNA microarray data generated by the Canadian Stem Cell Network to facil

Externí odkaz: https://doaj.org/article/e7949a0c09e74655949bcb4fed8528d1

Gene function in early mouse embryonic stem cell differentiation

Autor: Campbell Pearl A, Muro Enrique M, Perez-Iratxeta Carolina, Palidwor Gareth, Porter Christopher J, Sene Kagnew, Rudnicki Michael A, Andrade-Navarro Miguel A

Publikováno v: BMC Genomics, Vol 8, Iss 1, p 85 (2007)

Abstract Background Little is known about the genes that drive embryonic stem cell differentiation. However, such knowledge is necessary if we are to exploit the therapeutic potential of stem cells. To uncover the genetic determinants of mouse embryo

Externí odkaz: https://doaj.org/article/b58bac1fa3bf4e529dab99fd674d9b99

Accuracy and reproducibility of somatic point mutation calling in clinical-type targeted sequencing data.

Autor: Karimnezhad A; Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, K1H8L6, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, K1H8M5, Canada., Palidwor GA; Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, K1H8L6, Canada., Thavorn K; Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, K1H8L6, Canada.; School of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Crescent, Ottawa, K1G5Z3, Canada., Stewart DJ; The Ottawa Hospital, 501 Smyth Road, Ottawa, K1H8L6, Canada., Campbell PA; Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, K1H8L6, Canada., Lo B; The Ottawa Hospital, 501 Smyth Road, Ottawa, K1H8L6, Canada., Perkins TJ; Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, K1H8L6, Canada. tperkins@ohri.ca.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, K1H8M5, Canada. tperkins@ohri.ca.

Publikováno v: BMC medical genomics [BMC Med Genomics] 2020 Oct 15; Vol. 13 (1), pp. 156. Date of Electronic Publication: 2020 Oct 15.

Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis.

Autor: Rothberg JLM; 1The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6 Canada.; 2Ottawa Institute of Systems Biology, Ottawa, ON Canada.; 3Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON Canada., Maganti HB; 1The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6 Canada.; 2Ottawa Institute of Systems Biology, Ottawa, ON Canada.; 4Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON Canada., Jrade H; 1The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6 Canada.; 2Ottawa Institute of Systems Biology, Ottawa, ON Canada.; 3Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON Canada., Porter CJ; 5Ottawa Bioinformatics Core Facility, The Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6 Canada., Palidwor GA; 5Ottawa Bioinformatics Core Facility, The Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6 Canada., Cafariello C; 1The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6 Canada.; 2Ottawa Institute of Systems Biology, Ottawa, ON Canada.; 3Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON Canada., Battaion HL; 1The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6 Canada.; 2Ottawa Institute of Systems Biology, Ottawa, ON Canada.; 3Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON Canada., Khan ST; 1The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6 Canada., Perkins TJ; 1The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6 Canada.; 4Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON Canada.; 5Ottawa Bioinformatics Core Facility, The Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6 Canada., Paulson RF; 6Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA 16802 USA., Ito CY; 1The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6 Canada.; 3Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON Canada., Stanford WL; 1The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6 Canada.; 2Ottawa Institute of Systems Biology, Ottawa, ON Canada.; 3Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON Canada.; 4Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON Canada.

Publikováno v: Cell discovery [Cell Discov] 2018 May 01; Vol. 4, pp. 21. Date of Electronic Publication: 2018 May 01 (Print Publication: 2018).

Functional and genomic analyses of alpha-solenoid proteins.

Autor: Fournier D; Max-Delbrück Center for Molecular Medicine, Berlin, Germany., Palidwor GA, Shcherbinin S, Szengel A, Schaefer MH, Perez-Iratxeta C, Andrade-Navarro MA

Publikováno v: PloS one [PLoS One] 2013 Nov 21; Vol. 8 (11), pp. e79894. Date of Electronic Publication: 2013 Nov 21 (Print Publication: 2013).