TRIM28 inactivation in epithelial nephroblastoma is frequent and often associated with predisposing TRIM28 germline variants.

Autor: Wegert J; Theodor-Boveri-Institute/Biocenter, Developmental Biochemistry, University of Wuerzburg, Wuerzburg, Germany., Fischer AK; Department of Pathology, University of Cologne, Cologne, Germany., Palhazi B; Theodor-Boveri-Institute/Biocenter, Developmental Biochemistry, University of Wuerzburg, Wuerzburg, Germany., Treger TD; Wellcome Sanger Institute, Hinxton, UK.; Department of Paediatrics, University of Cambridge, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Hilgers C; Department of Pathology, Section of Pediatric Pathology, University of Bonn, Bonn, Germany., Ziegler B; Theodor-Boveri-Institute/Biocenter, Developmental Biochemistry, University of Wuerzburg, Wuerzburg, Germany., Jung H; Wellcome Sanger Institute, Hinxton, UK., Jüttner E; Department of Pathology, Schleswig-Holstein University Hospital, Kiel, Germany., Waha A; Department of Neuropathology, University of Bonn, Bonn, Germany., Fuchs J; Department of Pediatric Surgery and Pediatric Urology, University Children's Hospital Tübingen, Tübingen, Germany., Warmann SW; Department of Pediatric Surgery and Pediatric Urology, University Children's Hospital Tübingen, Tübingen, Germany., Frühwald MC; Swabian Children's Cancer Center, Pediatrics and Adolescent Medicine, University Hospital Augsburg, Augsburg, Germany., Hubertus J; Department of Pediatric Surgery at Marienhospital Witten, Ruhr-University Bochum, Witten, Germany., Pritchard-Jones K; UCL Great Ormond Street Institute of Child Health, University College London, London, UK., Graf N; Department of Paediatric Haematology and Oncology, Saarland University Hospital, Homburg, Germany., Behjati S; Wellcome Sanger Institute, Hinxton, UK.; Department of Paediatrics, University of Cambridge, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Furtwängler R; Department of Paediatric Haematology and Oncology, Saarland University Hospital, Homburg, Germany.; Pediatric Hematology and Oncology, Inselspital Children's Hospital, University Bern, Bern, Switzerland., Gessler M; Theodor-Boveri-Institute/Biocenter, Developmental Biochemistry, University of Wuerzburg, Wuerzburg, Germany.; Comprehensive Cancer Center Mainfranken, University of Wuerzburg, Wuerzburg, Germany., Vokuhl C; Department of Pathology, Section of Pediatric Pathology, University of Bonn, Bonn, Germany.

Publikováno v: The Journal of pathology [J Pathol] 2024 Jan; Vol. 262 (1), pp. 10-21. Date of Electronic Publication: 2023 Oct 04.

1258P - Analysis of molecular profile complexities for immunotherapy decision support

Autor: Dóczi, R. ¹, Tihanyi, D. ², Filotas, P. ¹, Dirner, A. ¹, Pálházi, B. ¹, Várkondi, E. ³, Farkas, Z. ³, Deri, J. ⁴, Lengyel, E. ⁵, Hegedus, C. ¹, Petak, I. ³

Publikováno v: In Annals of Oncology October 2019 30 Supplement 5:v512-v512

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TRIM28 in cancer and cancer therapy.

Autor: Kailang Li, Haifeng Wang, Bitao Jiang, Xiaofeng Jin

Publikováno v: Frontiers in Genetics; 2024, p1-16, 16p

Wilms tumour resulting from paternal transmission of a TRIM28 pathogenic variant-A first report.

Autor: Whitworth J; University of Cambridge Department of Medical Genetics, Box 238 Level 6, Addenbrooke's Treatment Centre, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, UK. jww39@cam.ac.uk.; Department of Clinical Genetics, Box 134 Level 6, Addenbrooke's Treatment Centre, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, UK. jww39@cam.ac.uk., Armstrong R; Department of Clinical Genetics, Box 134 Level 6, Addenbrooke's Treatment Centre, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, UK., Maher ER; University of Cambridge Department of Medical Genetics, Box 238 Level 6, Addenbrooke's Treatment Centre, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, UK.; Department of Clinical Genetics, Box 134 Level 6, Addenbrooke's Treatment Centre, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, UK.; Aston Medical School, Aston University, Birmingham, B4 7ET, UK.

Publikováno v: European journal of human genetics : EJHG [Eur J Hum Genet] 2024 Mar; Vol. 32 (3), pp. 361-364. Date of Electronic Publication: 2024 Jan 29.