The Nucleosome Remodeling and Deacetylase Complex NuRD Is Built from Preformed Catalytically Active Sub-modules

Autor: Zhang, W., Aubert, A., Gomez de Segura, J.M., Karuppasamy, M., Basu, S., Murthy, A.S., Diamante, A., Drury, T.A., Balmer, J., Cramard, J., Watson, A.A., Lando, D., Lee, S.F., Palayret, M., Kloet, S.L., Smits, A.H., Deery, M.J., Vermeulen, M., Hendrich, B., Klenerman, D., Schaffitzel, C., Berger, I., Laue, E.D.

Publikováno v: In Journal of Molecular Biology 17 July 2016 428(14):2931-2942

Initiation of T cell signaling by CD45 segregation at ‘close contacts’

Autor: Davis, SJ, Chang, VT, Fernandes, RA, Ganzinger, KA, Lee, SF, Siebold, C, McColl, M, Jonsson, P, Palayret, M, Harlos, K, Coles, CH, Jones, EY, Lui, Y, Huang, E, Gilbert, RJC, Klenerman, D, Aricescu, AR

Publikováno v: Nature immunology
Nature Immunology; 17(5), pp 574-582 (2016)

It has been proposed that the local segregation of kinases and the tyrosine phosphatase CD45 underpins T cell antigen receptor (TCR) triggering, but how such segregation occurs and whether it can initiate signaling is unclear. Using structural and bi

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The Nucleosome Remodeling and Deacetylase Complex NuRD Is Built from Preformed Catalytically Active Sub-modules

Autor: Zhang, W., Aubert, A., Gomez de Segura, J.M., Karuppasamy, M., Basu, S., Murthy, A.S., Diamante, A., Drury, T.A., Balmer, J., Cramard, J., Watson, A.A., Lando, D., Lee, S.F., Palayret, M., Kloet, S.L., Smits, A.H., Deery, M.J., Vermeulen, M., Hendrich, B., Klenerman, D., Schaffitzel, C., Berger, I., Laue, E.D.

Publikováno v: Journal of Molecular Biology, 428, 14, pp. 2931-2942
Journal of Molecular Biology
Zhang, W, Aubert, A, Gomez de Segura, J M, Karuppasamy, M, Basu, S, Murthy, A, Diamante, A, Drury, T A, Balmer, J, Cramard, J, Watson, A A, Lando, D, Lee, S F, Palayret, M, Kloet, S, Smits, A, Deery, M, Vermeulen, M, Hendrich, B, Klenerman, D, Schaffitzel, C, Berger, I & Laue, E D 2016, ' The Nucleosome Remodeling and Deacetylase Complex NuRD is built from preformed catalytically active sub-modules ', Journal of Molecular Biology, vol. 428, no. 14, pp. 2931-2942 . https://doi.org/10.1016/j.jmb.2016.04.025
Journal of Molecular Biology, 428, 2931-2942

The nucleosome remodeling deacetylase (NuRD) complex is a highly conserved regulator of chromatin structure and transcription. Structural studies have shed light on this and other chromatin modifying machines, but much less is known about how they as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::64cd9086e1c57d92a803976d41e8f45e

The Nucleosome Remodeling and Deacetylase Complex NuRD Is Built from Preformed Catalytically Active Sub-modules

Autor: Zhang, W, Aubert, A, Gomez De Segura, JM, Karuppasamy, M, Basu, S, Murthy, A, Diamante, A, Drury, TA, Balmer, J, Cramard, J, Watson, AA, Lando, D, Lee, SF, Palayret, M, Kloet, S, Smits, A, Deery, M, Vermeulen, M, Hendrich, B, Klenerman, D, Schaffitzel, C, Berger, I, Laue, ED

The nucleosome remodeling deacetylase (NuRD) complex is a highly conserved regulator of chromatin structure and transcription. Structural studies have shed light on this and other chromatin modifying machines, but much less is known about how they as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21b4b5e1c5b522b09bb89a4d990167e0