Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Palanikumar Ravindran"'
4
Akademický článek
Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B.
Autor: Simon P Fletcher, Daniel J Chin, Lore Gruenbaum, Hans Bitter, Erik Rasmussen, Palanikumar Ravindran, David C Swinney, Fabian Birzele, Roland Schmucki, Stefan H Lorenz, Erhard Kopetzki, Jade Carter, Miriam Triyatni, Linta M Thampi, Junming Yang, Dalal AlDeghaither, Marta G Murreddu, Paul Cote, Stephan Menne
Publikováno v: PLoS Pathogens, Vol 11, Iss 9, p e1005103 (2015)
Recombinant interferon-alpha (IFN-α) is an approved therapy for chronic hepatitis B (CHB), but the molecular basis of treatment response remains to be determined. The woodchuck model of chronic hepatitis B virus (HBV) infection displays many charact
Externí odkaz: https://doaj.org/article/490241e2b789474f94c1b6547a08b2f4
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5
Akademický článek
Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for 'active' disease.
Autor: Ruoqi Peng, Sriram Sridhar, Gaurav Tyagi, Jonathan E Phillips, Rosario Garrido, Paul Harris, Lisa Burns, Lorena Renteria, John Woods, Leena Chen, John Allard, Palanikumar Ravindran, Hans Bitter, Zhenmin Liang, Cory M Hogaboam, Chris Kitson, David C Budd, Jay S Fine, Carla M T Bauer, Christopher S Stevenson
Publikováno v: PLoS ONE, Vol 8, Iss 4, p e59348 (2013)
The preclinical model of bleomycin-induced lung fibrosis, used to investigate mechanisms related to idiopathic pulmonary fibrosis (IPF), has incorrectly predicted efficacy for several candidate compounds suggesting that it may be of limited value. As
Externí odkaz: https://doaj.org/article/f1de7e184b004255ba62f718b13adc00
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6
Akademický článek
Expression profiling of human immune cell subsets identifies miRNA-mRNA regulatory relationships correlated with cell type specific expression.
Autor: Florence Allantaz, Donavan T Cheng, Tobias Bergauer, Palanikumar Ravindran, Michel F Rossier, Martin Ebeling, Laura Badi, Bernhard Reis, Hans Bitter, Matilde D'Asaro, Alberto Chiappe, Sriram Sridhar, Gonzalo Duran Pacheco, Michael E Burczynski, Denis Hochstrasser, Jacky Vonderscher, Thomas Matthes
Publikováno v: PLoS ONE, Vol 7, Iss 1, p e29979 (2012)
Blood consists of different cell populations with distinct functions and correspondingly, distinct gene expression profiles. In this study, global miRNA expression profiling was performed across a panel of nine human immune cell subsets (neutrophils,
Externí odkaz: https://doaj.org/article/a09b488f612142eb9150e0324b41df65
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7
Akademický článek
Systemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of disease severity.
Autor: Debra A Cockayne, Donavan T Cheng, Benjamin Waschki, Sriram Sridhar, Palanikumar Ravindran, Holly Hilton, Galina Kourteva, Hans Bitter, Sreekumar G Pillai, Sudha Visvanathan, Kai-Christian Müller, Olaf Holz, Helgo Magnussen, Henrik Watz, Jay S Fine
Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38629 (2012)
The identification and validation of biomarkers to support the assessment of novel therapeutics for COPD continues to be an important area of research. The aim of the current study was to identify systemic protein biomarkers correlated with measures
Externí odkaz: https://doaj.org/article/d670836d162341129c02f54fff4b294d
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