Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Palaniappa Nanjappan"'
Autor:
Kondareddiar Ramalingam, Natarajan Raju, Nancy J. Bogdan, Steve Eaton, Edmund R. Marinelli, Mathew A. Von Wronski, Thangavel Arunachalam, Sibylle Pochon, Palaniappa Nanjappan, Pillai Radhakrishna, Michael F. Tweedle, Adrian D. Nunn, Feng Yan, Karen E. Linder
Publikováno v:
Journal of Biological Chemistry. 281:5702-5710
Tuftsin, Thr-Lys-Pro-Arg (TKPR), is an immunostimulatory peptide with reported nervous system effects as well. We unexpectedly found that tuftsin and a higher affinity antagonist, TKPPR, bind selectively to neuropilin-1 and block vascular endothelial
Publikováno v:
Tetrahedron. 51:2875-2894
A series of 2-substituted-1,3-diaminopropanes ( 1b-1f, 1h ) have been synthesized as precursors to nitroimidazole-substituted 3,3,9,9-tetramethyl-4,8-diazaundecane-2,10-dione dioxime ( 21b, 21d, 21e and 26a-26c ) (Propylene Amine Oxime, PnAO) ligands
Autor:
Palaniappa Nanjappan, Thangavel Arunachalam, Kimberly Ramos, Edmund R. Marinelli, Tina Marie Skedzielewski, Michael F. Tweedle, Adrian D. Nunn, Karen E. Linder, Edmund Metcalfe, Rolf E. Swenson
Publikováno v:
Bioconjugate chemistry. 22(7)
Protease-cleavable peptides containing a suitable fluor/quencher (Fl/Q) pair are optically dark until cleaved by their target protease, generating fluorescence. This approach has been used with many Fl/Q pairs, but little has been reported with IRDye
Publikováno v:
Academic radiology. 9
The future of contrast agents probably resides not only in their ability to highlight a lesion but also to characterize it and discriminate between various functional status at the molecular level. The high sensitivity of ultrasound (US) contrast ima
Autor:
K. Ramalingam, W. L. Rumsey, Adrian D. Nunn, N. Raju, David P. Nowotnik, Pirro John P, Palaniappa Nanjappan, K. E. Linder, W. Zeng
Publikováno v:
Journal of medicinal chemistry. 37(24)
We have developed a 99mTechnetium complex for imaging of hypoxic tissue (BMS-181321). Recently, another nitroimidazole derivative, based upon a bis(amine-phenol) ligand, was described in the patent literature. To compare this compound to BMS-181321,
Autor:
Tina Marie Skedzielewski, Karen E. Linder, Thangavel Arunachalam, A. D. Nunn, Kimberly Ramos, Palaniappa Nanjappan, Edmund Metcalfe, Michael F. Tweedle, Rolf E. Swenson
Publikováno v:
Contrast Media & Molecular Imaging. 4:265-265