Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Palak N. Patel"'
Autor:
Palak N. Patel, Thayne H. Dickey, Ababacar Diouf, Nichole D. Salinas, Holly McAleese, Tarik Ouahes, Carole A. Long, Kazutoyo Miura, Lynn E. Lambert, Niraj H. Tolia
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Apical membrane antigen 1 (AMA1) is a key malaria vaccine candidate and target of neutralizing antibodies. AMA1 binds to a loop in rhoptry neck protein 2 (RON2L) to form the moving junction during parasite invasion of host cells, and this co
Externí odkaz:
https://doaj.org/article/e25790efa50d468795dd8e573113c770
Autor:
Palak N. Patel, Thayne H. Dickey, Christine S. Hopp, Ababacar Diouf, Wai Kwan Tang, Carole A. Long, Kazutoyo Miura, Peter D. Crompton, Niraj H. Tolia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The Plasmodium falciparum Merozoite Surface Protein 1 (MSP-1) is a prime vaccine candidate for malaria. Here, the authors structurally and functionally characterise a panel of naturally acquired MSP-1 specific antibodies to identify one with potent b
Externí odkaz:
https://doaj.org/article/531c632caf744568b96ae1a66ae3b555
Publikováno v:
International Journal of Biological Macromolecules. 220:613-626
The extracellular insoluble deposits of highly ordered cross-β-structure-containing amyloid fibrils form the pathological basis for protein misfolding diseases. As amyloid fibrils are cytotoxic, inhibition of the process is a therapeutic strategy. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b7dee7196cdd64bcce96a1cd46f862
https://doi.org/10.1016/j.ijbiomac.2022.08.089
https://doi.org/10.1016/j.ijbiomac.2022.08.089
Autor:
Niraj H. Tolia, Palak N Patel
Publikováno v:
Expert Review of Vaccines. 20:199-214
Introduction: The development of effective vaccines remains a major health priority to combat the global burden of malaria, a life-threatening disease caused by Plasmodium parasites. Transmission-blocking vaccines (TBVs) elicit antibodies that neutra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71687e45c2049202e523aa03d88a0cc1
https://doi.org/10.1080/14760584.2021.1873135
https://doi.org/10.1080/14760584.2021.1873135