Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Palak G. Patel"'
Autor:
Robert Siddaway, Scott Milos, Arun Kumaran Anguraj Vadivel, Tara H. W. Dobson, Jyothishmathi Swaminathan, Scott Ryall, Sanja Pajovic, Palak G. Patel, Javad Nazarian, Oren Becher, Michael Brudno, Arun Ramani, Vidya Gopalakrishnan, Cynthia Hawkins
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Targeting genetic drivers of high grade diffuse glioma (HGG) has not improved patient survival, suggesting the involvement of other mechanisms. Here, across cancer types, the authors identify increased alternative splicing burden in cancer drivers co
Externí odkaz:
https://doaj.org/article/16682e61ebb34dd9b0ee5d0b70707f1e
Autor:
Walead Ebrahimizadeh, Karl-Philippe Guérard, Shaghayegh Rouzbeh, Eleonora Scarlata, Fadi Brimo, Palak G. Patel, Tamara Jamaspishvili, Lucie Hamel, Armen G. Aprikian, Anna Y. Lee, David M. Berman, John M. S. Bartlett, Simone Chevalier, Jacques Lapointe
Publikováno v:
British Journal of Cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0568e14e7646d2bce1d3d62e59885af2
https://doi.org/10.1038/s41416-023-02236-8
https://doi.org/10.1038/s41416-023-02236-8
Autor:
Afrakoma Afriyie-Asante, Palak G. Patel, Madhuri Koti, Eun Young Kang, Rachel Sue-A-Quan, May Phyo Nyi Nyi, Noor Shakfa, Martin Köbel
Publikováno v:
Gynecologic oncology. 162(2)
Objective To define the pre-treatment tumour immune landscape of clear cell carcinoma of the ovary (CCOC). Methods We investigated the infiltration profiles of selected immune cell populations and immune checkpoint proteins that have been previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3626aa4d837986433ae9656f1b8c1a
https://pubmed.ncbi.nlm.nih.gov/34088514
https://pubmed.ncbi.nlm.nih.gov/34088514
Autor:
Stephanie Harmon, Peter L. Choyke, Rachael Iseman, Tamara Jamaspishvili, David M. Berman, Thiago Vidotto, Thomas Sanford, Samira Masoudi, Jeremy A. Squire, Clarissa Gondim Picanço, Sherif Mehralivand, Baris Turkbey, Palak G. Patel, Isabelle Caven
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Mod Pathol
Universidade de São Paulo (USP)
instacron:USP
Mod Pathol
Phosphatase and tensin homolog (PTEN) loss is associated with adverse outcomes in prostate cancer and has clinical potential as a prognostic biomarker. The objective of this work was to develop an artificial intelligence (AI) system for automated det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a6a75d483eef76ddaea5ec2a870987
Autor:
Winnie Fu, Nathan E How, David M. Berman, Rachel Livergant, Thiago Vidotto, D. Robert Siemens, Liana B. Guedes, Palak G. Patel, Tamara Jamaspishvili, Anne Marie Mes-Masson, Tamara L. Lotan, Veronique Ouellet, Rodolfo Borges dos Reis, Madhuri Koti, Fred Saad, John B. A. Okello, Atsunari Kawashima, Clarissa Gondim Picanço, Jeremy A. Squire, Yingwei P. Peng, Yi Niu, Isabelle Caven
Publikováno v:
J Natl Cancer Inst
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Background Phosphatase and tensin homolog (PTEN) loss has long been associated with adverse findings in early prostate cancer. Studies to date have yet to employ quantitative methods (qPTEN) for measuring of prognostically relevant amounts of PTEN lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0d058142c5934fa49a3e86f74969c9
https://pubmed.ncbi.nlm.nih.gov/32129860
https://pubmed.ncbi.nlm.nih.gov/32129860
Autor:
David M. Berman, Armen Aprikian, Simone Chevalier, Walead Ebrahimizadeh, Palak G. Patel, Karl-Philippe Guérard, Tamara Jamaspishvili, Eleonora Scarlata, Jacques Lapointe, John M. S. Bartlett, Shaghayegh Rouzbeh, Yogesh M Bramhecha, Fadi Brimo
Publikováno v:
The Journal of molecular diagnostics : JMD. 22(10)
DNA copy number alterations (CNAs) are promising biomarkers to predict prostate cancer (PCa) outcome. However, fluorescence in situ hybridization (FISH) cannot assess complex CNA signatures because of low multiplexing capabilities. Multiplex ligation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb480ab97abda641a18d662ceb6afb05
https://pubmed.ncbi.nlm.nih.gov/32763409
https://pubmed.ncbi.nlm.nih.gov/32763409
Autor:
Winnie Fu, Palak G. Patel, Madhuri Koti, David M. Berman, Clarissa Gondim Picanço, Tamara Jamaspishvili, Yingwei Peng, Thiago Vidotto, Anne Marie Mes-Masson, Yi Niu, Fred Saad, Tamara L. Lotan, Rachel Livergant, Jeremy A. Squire, Nathan E How, Isabelle Caven, Veronique Ouellet, Rodolfo Borges dos Reis
Publikováno v:
Journal of Urology. 201
INTRODUCTION AND OBJECTIVES:Loss of the PTEN tumor suppressor is a powerful prognostic biomarker in prostate cancer. However, the significance of tumour heterogeneity and partial loss are not clear...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfc59c3d7844fa4b2fad0525ce5de5e1
https://doi.org/10.1097/01.ju.0000555707.15264.f6
https://doi.org/10.1097/01.ju.0000555707.15264.f6
Autor:
Laura A. Lee, Tanya Sack, Robert J. Gooding, Rachel Dunn, Joseph L. Chin, Atsunari Kawashima, Audrey Ellis, Karl-Philippe Guérard, Elizabeth Marra, Glenn Bauman, Vinolia Arthur-Hayward, Chelsea L. Jackson, Fadi Brimo, Simone Chevalier, Khurram M. Siddiqui, David M. Berman, Karen Mackie, Thomas Wessel, Dan Dion, Tamara Jamaspishvili, Suzanne Boursalie, Anna Ying-Wah Lee, Lee-Anne Pickard, Jacques Lapointe, Palak G. Patel, Eleonora Scarlata, Nathan E How, John M. S. Bartlett, John B. A. Okello, Khalil Hetou, Madeleine Moussa, Paul C. Boutros
Publikováno v:
Medical Biophysics Publications
Patel, P G, Wessel, T, Kawashima, A, Okello, J B, Jamaspishvili, T, Guerard, K-P, Lee, L, Ying-Wah Lee, A, E. How, N, Dion, D, Scarlata, E, L. Jackson, C, Boursalie, S, Sack, T, Dunn, R, Moussa, M, Mackie, K, Ellis, A, Marra, E, Chin, J, Siddiqui, K, Hetou, K, Pickard, L-A, Arthur Hayward, V, Bauman, G, Chevalier, S, Brimo, F, Boutros, P, Lapointe, J, Bartlett, J, J. Gooding, R & M. Berman, D 2019, ' A three gene DNA methylation biomarker accurately classifies early stage prostate cancer ', Prostate . https://doi.org/10.1002/pros.23895
Patel, P G, Wessel, T, Kawashima, A, Okello, J B, Jamaspishvili, T, Guerard, K-P, Lee, L, Ying-Wah Lee, A, E. How, N, Dion, D, Scarlata, E, L. Jackson, C, Boursalie, S, Sack, T, Dunn, R, Moussa, M, Mackie, K, Ellis, A, Marra, E, Chin, J, Siddiqui, K, Hetou, K, Pickard, L-A, Arthur Hayward, V, Bauman, G, Chevalier, S, Brimo, F, Boutros, P, Lapointe, J, Bartlett, J, J. Gooding, R & M. Berman, D 2019, ' A three gene DNA methylation biomarker accurately classifies early stage prostate cancer ', Prostate . https://doi.org/10.1002/pros.23895
Background We identify and validate accurate diagnostic biomarkers for prostate cancer through a systematic evaluation of DNA methylation alterations. Materials and methods We assembled three early prostate cancer cohorts (total patients = 699) from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ff13d6577bd2a95ff43c8114d9bb6f
https://pubmed.ncbi.nlm.nih.gov/31433512
https://pubmed.ncbi.nlm.nih.gov/31433512
Autor:
David M. Berman, Jacques Lapointe, Anna Yw Lee, Tamara Jamaspishvili, Dan Dion, Laura A. Lee, Simone Chevalier, Nadia Boufaied, Vasundara Venkateswaran, Paul C. Boutros, Palak G. Patel, Paul C. Park, Karl-Philippe Guérard, Axel A. Thomson, Walead Ebrahimizadeh, John M. S. Bartlett, Jane Bayani, Robert Lesurf, Fadi Brimo, Ralph Buttyan
Publikováno v:
Journal of Clinical Oncology. 39:209-209
209 Background: Histopathologic investigation of diagnostic prostate biopsies both confirms the presence of disease and estimates its potential for distal spread via tumour grade. The accuracy of biopsy grading is limited by intra-tumoral heterogenei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c96b16ce5fc611496f22ffd3ddc8ac48
https://doi.org/10.1200/jco.2021.39.6_suppl.209
https://doi.org/10.1200/jco.2021.39.6_suppl.209
Autor:
Andrew G. Hatch, Palak G. Patel, David M. Berman, Loni Pickle, Aren Ewing, Zunping Luo, Mark Andersen, Fiona Hyland
Publikováno v:
Cancer Research. 80:158-158
Changes in DNA methylation, causing chromosome instability and altered gene expression, have been strongly associated with carcinogenesis. Due to the involvement of methylation in cancer, methylation profiles have been heralded as promising cancer bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3fbccb27320f661c74446dbd3a18ac7
https://doi.org/10.1158/1538-7445.am2020-158
https://doi.org/10.1158/1538-7445.am2020-158