Human Obesity Associated with an Intronic SNP in the Brain-Derived Neurotrophic Factor Locus.

Autor: Mou Z; Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA; Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA., Hyde TM; The Lieber Institute for Brain Development, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Lipska BK; Human Brain Collection Core, National Institute of Mental Health (NIMH), NIH, Bethesda, MD 20892, USA., Martinowich K; The Lieber Institute for Brain Development, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Wei P; Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA; Departments of Neurology and Physical Medicine and Rehabilitation, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA., Ong CJ; Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA; Departments of Neurology and Physical Medicine and Rehabilitation, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA., Hunter LA; Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA; Departments of Neurology and Physical Medicine and Rehabilitation, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA., Palaguachi GI; Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA; Departments of Neurology and Physical Medicine and Rehabilitation, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA., Morgun E; Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA; Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA., Teng R; Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA., Lai C; Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA; Departments of Neurology and Physical Medicine and Rehabilitation, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA., Condarco TA; Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA., Demidowich AP; Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA., Krause AJ; Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA., Marshall LJ; Preclinical Microbicide & Prevention Research Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA., Haack K; Department of Genetics, Texas Biomedical Research Institute and Southwest National Primate Research Center, San Antonio, TX 78245, USA., Voruganti VS; Department of Genetics, Texas Biomedical Research Institute and Southwest National Primate Research Center, San Antonio, TX 78245, USA; Department of Nutrition and UNC Nutrition Research Institute, University of North Carolina, Chapel Hill, Kannapolis, NC 28081, USA., Cole SA; Department of Genetics, Texas Biomedical Research Institute and Southwest National Primate Research Center, San Antonio, TX 78245, USA., Butte NF; USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX 77030, USA., Comuzzie AG; Department of Genetics, Texas Biomedical Research Institute and Southwest National Primate Research Center, San Antonio, TX 78245, USA., Nalls MA; Molecular Genetics Section, National Institute of Aging (NIA), Bethesda, MD 20892, USA., Zonderman AB; Behavioral Epidemiology Section, NIA, Baltimore, MD 21224, USA., Singleton AB; Molecular Genetics Section, National Institute of Aging (NIA), Bethesda, MD 20892, USA., Evans MK; Health Disparities Research Section, NIA, Baltimore, MD 21224, USA., Martin B; Metabolism Unit, NIA, Baltimore, MD 21224, USA., Maudsley S; Receptor Pharmacology Unit, NIA, Baltimore, MD 21224, USA; Translational Neurobiology Group, VIB Department of Molecular Genetics, University of Antwerp, 2610 Wilrijk, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, 2610 Wilrijk, Belgium., Tsao JW; Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA; Departments of Neurology and Physical Medicine and Rehabilitation, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA; Department of Neurology, University of Tennessee Health Science Center, Memphis, TN 38163, USA., Kleinman JE; The Lieber Institute for Brain Development, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Yanovski JA; Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA., Han JC; Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA; Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA; Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN 38103, USA. Electronic address: jhan14@uthsc.edu.

Publikováno v: Cell reports [Cell Rep] 2015 Nov 10; Vol. 13 (6), pp. 1073-1080. Date of Electronic Publication: 2015 Oct 29.

Brain-derived neurotrophic factor in human subjects with function-altering melanocortin-4 receptor variants.

Autor: Hohenadel MG; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIH), Phoenix, AZ, USA., Thearle MS; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIH), Phoenix, AZ, USA., Grice BA; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIH), Phoenix, AZ, USA., Huang H; Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA., Dai MH; Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA., Tao YX; Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA., Hunter LA; 1] Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA [2] Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA., Palaguachi GI; 1] Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA [2] Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA., Mou Z; 1] Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA [2] Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA., Kim RC; 1] Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA [2] Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA., Tsang MM; 1] Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA [2] Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA., Haack K; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX, USA., Voruganti VS; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX, USA., Cole SA; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX, USA., Butte NF; USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX, USA., Comuzzie AG; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX, USA., Muller YL; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIH), Phoenix, AZ, USA., Baier LJ; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIH), Phoenix, AZ, USA., Krakoff J; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIH), Phoenix, AZ, USA., Knowler WC; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIH), Phoenix, AZ, USA., Yanovski JA; Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA., Han JC; 1] Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA [2] Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.

Publikováno v: International journal of obesity (2005) [Int J Obes (Lond)] 2014 Aug; Vol. 38 (8), pp. 1068-74. Date of Electronic Publication: 2013 Nov 26.