Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Pal Rongved"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 2156-2160 (2019)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
We present a short and efficient way of synthesizing two synthetically versatile 4-quinolone-3-carboxylate building blocks by cyclopropanation-ring expansion of 3-chloroindoles with α-halodiazoacetates as the key step. This novel transformation was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e11623c18642081f015d1329bb75086
https://doi.org/10.3762/bjoc.15.212
https://doi.org/10.3762/bjoc.15.212
Autor:
Saïd Yous, Pal Rongved, Samar Issa, Marc Le Borgne, Nicolas Bedel, Zouhair Bouaziz, Anthony Prandina
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, 34 (1), pp.1321-1346. ⟨10.1080/14756366.2019.1640692⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1321-1346 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2019, 34 (1), pp.1321-1346. ⟨10.1080/14756366.2019.1640692⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, 34 (1), pp.1321-1346. ⟨10.1080/14756366.2019.1640692⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1321-1346 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2019, 34 (1), pp.1321-1346. ⟨10.1080/14756366.2019.1640692⟩
International audience; For over half a century, the carbazole skeleton has been the key structural motif of many biologically active compounds including natural and synthetic products. Carbazoles have taken an important part in all the existing anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cfd9cb87fbb61e794dc4fdea723107a
http://europepmc.org/articles/PMC6691762
http://europepmc.org/articles/PMC6691762
Autor:
Christian Schnaars, Adriana Magalhaes Santos Andresen, Silje Lauksund, Christopher Fröhlich, Pal Rongved, Ole Andreas Økstad, Sandra Huber, Susann Skagseth, Tor Gjøen, Ørjan Samuelsen, Adam Heikal, Hanna-Kirsti S. Leiros, Ove Alexander Høgmoen Åstrand, Annette Bayer, Geir Kildahl-Andersen, Trine Josefine Olsen Carlsen, Sarah Finke
Publikováno v:
Antimicrobial Agents and Chemotherapy
Carbapenem-resistant Gram-negative pathogens are a critical public health threat and there is an urgent need for new treatments. Carbapenemases (β-lactamases able to inactivate carbapenems) have been identified in both serine β-lactamase (SBL) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be70d5ec4329bdb54e632d65b712aa9
https://hdl.handle.net/10037/18642
https://hdl.handle.net/10037/18642
Autor:
Sylvie Radix, Adriana Magalhaes Santos Andresen, Christopher Fröhlich, Christian Schnaars, Ole Andreas Økstad, Ørjan Samuelsen, Silje Lauksund, Anthony Prandina, Ove Alexander Høgmoen Åstrand, Adam Heikal, Roya Popal, Lars Petter Jordheim, Marc Le Borgne, Geir Kildahl-Andersen, Tor Gjøen, Pal Rongved
Publikováno v:
ACS Infectious Diseases
ACS Infectious Diseases, American Chemical Society, 2018, ⟨10.1021/acsinfecdis.8b00137⟩
ACS Infectious Diseases, American Chemical Society, 2018, ⟨10.1021/acsinfecdis.8b00137⟩
The rise of antimicrobial resistance (AMR) worldwide and the increasing spread of multi-drug-resistant organisms expressing metallo-β-lactamases (MBL) require the development of efficient and clinically available MBL inhibitors. At present, no such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a99720e5a1149d53c0d780d8118c69
https://doi.org/10.1021/acsinfecdis.8b00137
https://doi.org/10.1021/acsinfecdis.8b00137
Autor:
Christine Olsen, Frøydis Sved Skottvoll, Ole Kristian Brandtzaeg, Steven Ray Wilson, Christian Schnaars, Elsa Lundanes, Pal Rongved
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 7 (2019)
Frontiers in Chemistry, Vol 7 (2019)
Prior to mass spectrometry, on-line sample preparation can be beneficial to reduce manual steps, increase speed, and enable analysis of limited sample amounts. For example, bottom-up proteomics sample preparation and analysis can be accelerated by di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f535c8f7f21abe350812332b76cf4c13
https://pubmed.ncbi.nlm.nih.gov/31850321
https://pubmed.ncbi.nlm.nih.gov/31850321
Autor:
Pal Rongved, Marc Le Borgne, Lars Petter Jordheim, Christopher Fröhlich, Sylvie Radix, Ove Alexander Høgmoen Åstrand, Anthony Prandina, Tor Gjøen, Silje Lauksund, Christian Schnaars, Ørjan Samuelsen, Adriana Magalhaes Santos Andresen, Geir Kildahl-Andersen
Publikováno v:
MedChemComm
MedChemComm, Royal Society of Chemistry, In press, 10 (4), pp.528-537. ⟨10.1039/C8MD00578H⟩
MedChemComm, Royal Society of Chemistry, In press, 10 (4), pp.528-537. ⟨10.1039/C8MD00578H⟩
International audience; The syntheses of metallo-β-lactamase inhibitors comprising chelating moieties, with varying zinc affinities,and peptides partly inspired from bacterial peptide sequences, have been undertaken. The zinc chelatorstrength was va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eeeeb423d35ab7e14d9a5a80a9ccf4e
https://hal.archives-ouvertes.fr/hal-02077900
https://hal.archives-ouvertes.fr/hal-02077900
Autor:
Zineb Bousfiha, Espen Frøvold, Lars Petter Jordheim, Christopher Fröhlich, Anthony Prandina, Sylvie Radix, Ørjan Samuelsen, Ove Alexander Høgmoen Åstrand, Marc Le Borgne, Pal Rongved, Hanna-Kirsti S. Leiros
Publikováno v:
Tetrahedron
Tetrahedron, Elsevier, 2019, 75 (11), pp.1525-1540. ⟨10.1016/j.tet.2019.02.004⟩
Tetrahedron, Elsevier, 2019, 75 (11), pp.1525-1540. ⟨10.1016/j.tet.2019.02.004⟩
Antibiotics are key drugs in modern healthcare, especially in hospitals, where multiresistant bacteria resides and is a potential threat to human health. In the present work, a new series of adjuvants working synergistically with the carbapenem merop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e1b96f2ca9fcecb4e761c2469d38ab
https://hdl.handle.net/10037/17889
https://hdl.handle.net/10037/17889
Autor:
Simen Snellingen, Ove Alexander Høgmoen Åstrand, Tore Bonge-Hansen, Stein Ove Døskeland, Pal Rongved, Reidun Aesoy, Lars Herfindal, Misbah Sabir, Elvar Örn Viktorsson, Bendik Melling Grøthe, Anthony Prandina
Publikováno v:
Bioorganicmedicinal chemistry. 25(7)
A new efficient total synthesis of the phenazine 5,10-dioxide natural products iodinin and myxin and new compounds derived from them was achieved in few steps, a key-step being 1,6-dihydroxyphenazine di-N-oxidation. Analogues prepared from iodinin, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19dbffeadbf4faf10c58fe369c70fc7
https://pubmed.ncbi.nlm.nih.gov/28284865
https://pubmed.ncbi.nlm.nih.gov/28284865
Autor:
Pal Rongved, Ingebrigt Sylte, G. Hege Thoresen, Ingvei Gikling, Arild C. Rustan, Eili Tranheim Kase, Ove Alexander Høgmoen Åstrand
Publikováno v:
European Journal of Medicinal Chemistry. 74:258-263
Four new mimics of 22-S-hydroxycholesterol (22SHC) were synthesized and evaluated using molecular modeling and tested in human muscle cells (primary myotubes) and hepatocytes (HepG2 cells). The new compounds (9, 12, 15a and 15b) showed good interrela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103bf259a953b54819b9c8b7c4a81384
https://doi.org/10.1016/j.ejmech.2014.01.003
https://doi.org/10.1016/j.ejmech.2014.01.003
Autor:
Marcel Sandberg, Eili Tranheim Kase, Ingebrigt Sylte, Pal Rongved, G. Hege Thoresen, Carl Henrik Görbitz, O. Alexander H. Åstrand
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:643-650
The generic, synthetic oxysterol 22(S)-hydroxycholesterol (22SHC) has shown antagonistic effects towards liver X receptor (LXR) in vitro and promising effects on plasma triacylglycerol level and body weight-gain in animal studies.1,2 On the contrary,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c98423008478fba8b23aef1fdafa7de
https://doi.org/10.1016/j.bmc.2013.10.024
https://doi.org/10.1016/j.bmc.2013.10.024