Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Pal Papsai"'
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 11:974-990
The DNA interference pathways exhibited by cisplatin and related anticancer active metal complexes have been extensively studied. Much less is known to what extent RNA interaction pathways may operate in parallel, and perhaps contribute to both antin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f9966aec30ebf10f7691e0046c238a
https://doi.org/10.1007/s00775-006-0157-y
https://doi.org/10.1007/s00775-006-0157-y
Publikováno v:
Dalton Trans.. :3515-3517
The anticancer active complex cisplatin interacts preferentially with the common, G-C rich, wobble base pair region of both tRNA(Ala) and Mh(Ala) in a reaction that at pH 6.3 is rate limited by the acid hydrolysis of the metal complex.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43b1a2936a03ed462c23473e06eb286
https://doi.org/10.1039/b603833f
https://doi.org/10.1039/b603833f
Publikováno v:
Dalton transactions (Cambridge, England : 2003). (38)
Nuclear DNA is a well characterized target for many low molecular metal-based drugs, with cisplatin and related antineoplastic compounds as typical examples. Much less is known concerning to what extent targeting of RNA may influence the activity spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7ea80e1950b3e05a61d52e1f1af129
https://pubmed.ncbi.nlm.nih.gov/18813377
https://pubmed.ncbi.nlm.nih.gov/18813377
Autor:
Pal Papsai, Hanna K. Hedman, Veronika Jenei, Ute Jungwirth, Sofi K. C. Elmroth, Margareta Hägerlöf
Publikováno v:
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 13(3)
Wnt-5a is a secreted glycoprotein which has been shown to be involved in the regulation of cell adhesion and motility, processes which are of importance in metastasis formation by cancer cells. We here present an initial study aiming at evaluating wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca6e5c4acf840f110b1fb100d029a36
https://pubmed.ncbi.nlm.nih.gov/18058140
https://pubmed.ncbi.nlm.nih.gov/18058140
Publikováno v:
Dalton Transactions: An International Journal of Inorganic Chemistry; Jul2006, Vol. 2006 Issue 29, p3515-3517, 3p