Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Pal John Pal Adabala"'
Autor:
Pal John Pal Adabala, Yang Wang, Oluwafemi S. Akintola, Sandeep Bhosale, Robert Britton, Weiwu Ren, Yumeela Ganga-Sah, Andrew J. Bennet
Publikováno v:
ACS Catalysis. 11:9377-9389
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54a6869e0e41b070c1e7f0f6ae48f6cc
https://doi.org/10.1021/acscatal.1c01634
https://doi.org/10.1021/acscatal.1c01634
Autor:
Andrew J. Bennet, Pal John Pal Adabala, Oluwafemi S. Akintola, Sandeep Bhosale, Saeideh Shamsi Kazem Abadi
Publikováno v:
The Journal of organic chemistry. 85(5)
Glycoside hydrolases (GHs) catalyze hydrolyses of glycoconjugates in which the enzyme choreographs a series of conformational changes during the catalytic cycle. As a result, some GH families, including α-amylases (GH13), have their chemical steps c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9389cf8bcc69041790b9894988e1486
https://pubmed.ncbi.nlm.nih.gov/31994882
https://pubmed.ncbi.nlm.nih.gov/31994882
Autor:
Andrew J. Bennet, Saeideh Shamsi Kazem Abadi, Anuj K. Yadav, Pal John Pal Adabala, Saswati Chakladar, Michael Tran
Publikováno v:
Journal of the American Chemical Society. 139(31)
The design of covalent inhibitors in glycoscience research is important for the development of chemical biology probes. Here we report the synthesis of a new carbocyclic mechanism-based covalent inhibitor of an α-glucosidase. The enzyme efficiently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37069d94ee4a9a8e38feb5d1717ebc5f
https://pubmed.ncbi.nlm.nih.gov/28723089
https://pubmed.ncbi.nlm.nih.gov/28723089
Exploitation of the catalytic site and 150 cavity for design of influenza A neuraminidase inhibitors
Publikováno v:
The Journal of organic chemistry. 78(21)
We report here the exploitation of the 150 cavity in the active site of influenza A viral neuraminidases for the design of novel C-6 triazole-containing Tamiflu derivatives. A general and convenient synthetic route was developed by utilizing a highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229dffaf4a3b532ff83189692748829b
https://pubmed.ncbi.nlm.nih.gov/24090215
https://pubmed.ncbi.nlm.nih.gov/24090215
Publikováno v:
The Journal of organic chemistry. 78(16)
The synthesis of a tetanus toxoid (TT)-conjugate of a hyaluronic acid (HA) hexasaccharide is described. The compound was intended for use in monitoring HA levels as a disease marker and as a potential vaccine against Group A Streptococcus (GAS) infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eaa34a4ea87a665be89e3b9ac588cef
https://pubmed.ncbi.nlm.nih.gov/23848545
https://pubmed.ncbi.nlm.nih.gov/23848545