Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Pal I Bauer"'
Autor:
Zsuzsanna A Dunai, Gergely Imre, Gabor Barna, Tamas Korcsmaros, Istvan Petak, Pal I Bauer, Rudolf Mihalik
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41945 (2012)
For a long time necrosis was thought to be an uncontrolled process but evidences recently have revealed that necrosis can also occur in a regulated manner. Necroptosis, a type of programmed necrosis is defined as a death receptor-initiated process un
Externí odkaz:
https://doaj.org/article/1344c6882ccc4285b45f765f794832c9
Autor:
Anna Fekete, Erzsebet Kenesi, Eva Hunyadi-Gulyas, Hajnalka Durgo, Barbara Berko, Zsuzsanna A Dunai, Pal I Bauer
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42690 (2012)
The important regulatory role of the guanine-quadruplex (GQ) structure, present in the nuclease hypersensitive element (NHE) III(1) region of the human c-myc (h c-myc) gene's promoter, in the regulation of the transcription of that gene has been docu
Externí odkaz:
https://doaj.org/article/a9cbec8ebcb7444ab1b570fbb822ded7
Publikováno v:
Pathology & Oncology Research. 17:791-800
Programmed cell death is a key component of tissue homeostasis, normal development and wide variety of diseases. Conventional view refers to programmed cell death form as caspase-mediated apoptosis while necrosis is considered as an accidental and un
Publikováno v:
Biochemical and Biophysical Research Communications. 366:568-573
Our results show that in the intact normal animal cell mitochondrial ATP is directly connected to nuclear PARP-1 by way of a specific adenylate kinase enzymatic path. This mechanism is demonstrated in two models: (a) by its inhibition with a specific
Autor:
Gergely Keszler, Tatjana Spasokoukotskaja, Szula Virga, Pal I. Bauer, Maria Sasvari-Szekely, Maria Staub
Publikováno v:
Archives of Biochemistry and Biophysics. 436:69-77
The inborn deficiency of adenosine deaminase is characterised by accumulation of excess amounts of cytotoxic deoxyadenine nucleotides in lymphocytes. Formation of dATP requires phosphorylation of deoxyadenosine by deoxycytidine kinase (dCK), the main
Publikováno v:
Journal of Biological Chemistry. 278:9235-9243
Survival and proliferation of cells of a human myelo-erythroid CD34+ leukemia cell line (TF-1) depend on the presence of granulocyte-macrophage colony-stimulating factor or interleukin-3. Upon hormone withdrawal these cells stop proliferating and und
Autor:
György Kéri, Stefaan Keppens, Attila Stetak, Wilfried Merlevede, Pal I. Bauer, Jackie R. Vandenheede, Peter Vandenabeele, Peter Csermely, Zita Krivickiene, Mindaugas Valius, Gyöngyi Bökönyi, Tibor Vántus, Wim Declercq
Publikováno v:
Cellular Signalling. 13:717-725
TT-232 is a somatostatin analogue containing a five-residue ring structure. The present report describes TT-232-induced signalling events in A431 cells, where a 4-h preincubation with the peptide irreversibly induced a cell death program, which invol
Autor:
Attila Juhasz, Miklós Patthy, Klára Németh, Irén Fauszt, Pal I. Bauer, Sandor Bajusz, Eva Barabas
Publikováno v:
Biopolymers. 51:109-118
Interleukin-1 beta (IL-1 beta)-converting enzyme (ICE, caspase-1) processes the IL-1 beta precursor to mature inflammatory cytokine IL-1 beta. ICE has been identified as a unique cysteine protease, which cleaves Asp-X bonds, shows resistance to E-64
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1338:100-106
A proteinase was isolated from calf thymus that degraded pADPRT, histone H1 and alpha-casein in a Ca(2+)-dependent manner. In a five-step procedure, a homogenous proteinase was obtained with a subunit structure of 80 and 30 kDa. The amino-acid homolo
Autor:
Michael O'Connor, E. Kirsten, Hector R. Wong, Pal I. Bauer, Andrew L. Salzman, C. Szabo, E. Kun, E. S. Vizi, G. Hasko, Basilia Zingarelli, J. Mendeleyev
Publikováno v:
Scopus-Elsevier
Chronic inflammation is known to facilitate carcinogenic transformation in various tissues. 5-iodo-6-amino-1,2-benzopyrone (INH2BP), a novel inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (pADPRT) has recently been shown to regulate a va