Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pal Boto"'
Autor:
Abdennour Douida, Frank Batista, Pal Boto, Zsolt Regdon, Agnieszka Robaszkiewicz, Krisztina Tar
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1629 (2021)
The conserved Blm10/PA200 proteins are proteasome activators. Previously, we identified PA200-enriched regions in the genome of SH-SY5Y neuroblastoma cells by chromatin immunoprecipitation (ChIP) and ChIP-seq analysis. We also found that selective mi
Externí odkaz:
https://doaj.org/article/79dbf140cc4f4f4d90177166df6333ee
Autor:
Renáta Bencsik, Pal Boto, Renáta Nóra Szabó, Bianka Monika Toth, Emilia Simo, Bálint László Bálint, Istvan Szatmari
Publikováno v:
Stem Cell Research, Vol 17, Iss 2, Pp 228-234 (2016)
Transgene-mediated programming is a preeminent strategy to direct cellular identity. To facilitate cell fate switching, lineage regulating genes must be efficiently and uniformly induced. However, gene expression is often heterogeneous in transgenic
Externí odkaz:
https://doaj.org/article/d0d243e1d2294199bb4eda1969895e7a
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5338 (2019)
Huntington’s disease (HD) is an inherited neurodegenerative disorder, caused by an abnormal polyglutamine (polyQ) expansion in the huntingtin protein (Htt). Mitochondrial dysfunction and impairment of the ubiquitin-proteasome system (UPS) are hallm
Externí odkaz:
https://doaj.org/article/b60bfd16dced48fc9ff61538386a1681
Zbtb46-dependent altered developmental program in embryonic stem cell-derived blood cell progenitors
Publikováno v:
Stem cells (Dayton, Ohio)REFERENCES. 39(10)
Zbtb46 is a recently identified dendritic cell (DC)-specific transcription factor with poorly defined biology. Although Zbtb46 is highly expressed in conventional DCs, evidence also points to its presence in erythroid progenitors and endothelial cell
Autor:
Petros Tzerpos, Pal Boto, Attila Bacsi, László Halász, Zsolt Czimmerer, Sascha Sauer, Istvan Szatmari, Anikó Nagy, Gyorgy Hajas, Bence Daniel, Wilhelm K. Berger, Attila Horvath, Gergely Nagy, Szilárd Póliska, Jean Francois-Deleuze, Laszlo Nagy, Zsuzsanna Kolostyak, Timea Cseh
Publikováno v:
Genes Dev
Macrophages polarize into functionally distinct subtypes while responding to microenvironmental cues. The identity of proximal transcription factors (TFs) downstream from the polarization signals are known, but their activity is typically transient,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d92b0c4debed4906c2bf9184106871
http://edoc.mdc-berlin.de/19495/1/19495oa.pdf
http://edoc.mdc-berlin.de/19495/1/19495oa.pdf
Publikováno v:
Critical Reviews in Immunology. 38:63-78
The transcription factor RUNX3 is a prominent regulator of multiple hematopoietic cell lineages. Gene loss of function studies demonstrated the unique and essential roles of this master regulator in differentiated lymphoid and myeloid cells. As a com
Autor:
Károly Jambrovics, Pál Botó, Attila Pap, Zsolt Sarang, Zsuzsanna Kolostyák, Zsolt Czimmerer, Istvan Szatmari, László Fésüs, Iván P. Uray, Zoltán Balajthy
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-10 (2023)
Abstract Atypically expressed transglutaminase 2 (TG2) has been identified as a poor prognostic factor in a variety of cancers. In this study, we evaluated the contribution of TG2 to the prolonged cell survival of differentiated acute promyelocytic l
Externí odkaz:
https://doaj.org/article/2af418809b3c4062a29a52c240c93479
Autor:
Gergely Nagy, Zsolt Czimmerer, Petros Tzerpos, Pal Boto, Mate Kiss, Massimiliano Mazzone, Attila Pap, Istvan Szatmari, Manuel Ehling, Laszlo Nagy, Zsuzsanna Kolostyak, Bence Daniel, Pawel Bieniasz-Krzywiec, Attila Horvath, Szilárd Póliska
Retinoid X receptor (RXR) regulates several key functions in myeloid cells, including inflammatory responses, phagocytosis, chemokine secretion, and proangiogenic activity. Its importance, however, in tumor-associated myeloid cells is unknown. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7e3c40d9e8907f868d6fb600d20e65
http://hdl.handle.net/2318/1841233
http://hdl.handle.net/2318/1841233
Autor:
Julianna Kobolák, Attila Pap, Erika Takács, Pal Boto, Istvan Szatmari, Szilvia Benko, Tamas Imre Csuth, Elek Gergő Kovács, Bianka Tóth, Hadas Raveh-Amit, Emilia Simo, Andras Dinnyes
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(1)
Application of dendritic cells (DCs) to prime responses to tumor Ags provides a promising approach to immunotherapy. However, only a limited number of DCs can be manufactured from adult precursors. In contrast, pluripotent embryonic stem (ES) cells r