A set of diagnostic tests for detection of active Babesia duncani infection.

Autor: Chand M; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, USA., Vydyam P; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, USA., Pal AC; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, USA., Thekkiniath J; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, USA., Darif D; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, USA., Li Z; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, USA., Choi JY; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, USA., Magni R; School of Systems Biology, George Mason University, Fairfax, USA., Luchini A; School of Systems Biology, George Mason University, Fairfax, USA., Tonnetti L; Scientific Affairs, American Red Cross, Rockville, USA., Horn EJ; Lyme Disease Biobank, Portland, USA., Tufts DM; Department of Infectious Diseases and Microbiology, University of Pittsburgh School of Public Health, Pittsburgh, USA; Department of Veterinary Tropical Diseases, University of Pretoria, Pretoria, South Africa., Ben Mamoun C; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, USA. Electronic address: choukri.benmamoun@yale.edu.

Publikováno v: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2024 Oct; Vol. 147, pp. 107178. Date of Electronic Publication: 2024 Jul 25.

Tafenoquine-Atovaquone Combination Achieves Radical Cure and Confers Sterile Immunity in Experimental Models of Human Babesiosis.

Autor: Vydyam P; Department of Infectious Diseases, School of Medicine, Yale University, New Haven, Connecticut, USA., Pal AC; Department of Infectious Diseases, School of Medicine, Yale University, New Haven, Connecticut, USA., Renard I; Department of Infectious Diseases, School of Medicine, Yale University, New Haven, Connecticut, USA., Chand M; Department of Infectious Diseases, School of Medicine, Yale University, New Haven, Connecticut, USA., Kumari V; Department of Infectious Diseases, School of Medicine, Yale University, New Haven, Connecticut, USA., Gennaro JC; Department of Infectious Diseases, School of Medicine, Yale University, New Haven, Connecticut, USA., Mamoun CB; Department of Infectious Diseases, School of Medicine, Yale University, New Haven, Connecticut, USA.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2024 Jan 12; Vol. 229 (1), pp. 161-172.

Epitope profiling of monoclonal antibodies to the immunodominant antigen BmGPI12 of the human pathogen Babesia microti .

Autor: Chand M; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States., Choi JY; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States., Pal AC; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States., Singh P; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States., Kumari V; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States., Thekkiniath J; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States., Gagnon J; L2 Diagnostics, LLC, New Haven, CT, United States., Timalsina S; L2 Diagnostics, LLC, New Haven, CT, United States., Gaur G; L2 Diagnostics, LLC, New Haven, CT, United States., Williams S; Department of Forestry and Horticulture, Connecticut Agricultural Experiment Station, New Haven, CT, United States., Ledizet M; L2 Diagnostics, LLC, New Haven, CT, United States., Mamoun CB; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, United States.

Publikováno v: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2022 Nov 25; Vol. 12, pp. 1039197. Date of Electronic Publication: 2022 Nov 25 (Print Publication: 2022).

High-resolution crystal structure and chemical screening reveal pantothenate kinase as a new target for antifungal development.

Autor: Gihaz S; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA., Gareiss P; Yale Center for Molecular Discovery, Yale West Campus, West Haven, CT 06516, USA., Choi JY; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA., Renard I; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA., Pal AC; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA., Surovsteva Y; Yale Center for Molecular Discovery, Yale West Campus, West Haven, CT 06516, USA., Chiu JE; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA., Thekkiniath J; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA., Plummer M; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA., Hungerford W; Yale Center for Molecular Discovery, Yale West Campus, West Haven, CT 06516, USA., Montgomery ML; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Hosford A; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA; Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Adams EM; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA; Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Lightfoot JD; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA; Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Fox D 3rd; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, WA 98109, USA; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA; UCB Pharma, 7869 NE Day Road West, Bainbridge Island, WA 98110, USA., Ojo KK; Center for Emerging & Re-emerging Infectious Disease, Division of Allergy & Infectious Disease, Department of Medicine, University of Washington, Seattle, WA 98109, USA., Staker BL; Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle, WA 98109, USA; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA 98109, USA., Fuller K; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA; Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA., Ben Mamoun C; Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: choukri.benmamoun@yale.edu.

Publikováno v: Structure (London, England : 1993) [Structure] 2022 Nov 03; Vol. 30 (11), pp. 1494-1507.e6. Date of Electronic Publication: 2022 Sep 26.

Specific and Sensitive Diagnosis of Babesia microti Active Infection Using Monoclonal Antibodies to the Immunodominant Antigen BmGPI12.

Autor: Gagnon J; L2 Diagnostics, LLC, New Haven, Connecticut, USA., Timalsina S; L2 Diagnostics, LLC, New Haven, Connecticut, USA., Choi JY; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicinegrid.471390.8, New Haven, Connecticut, USA., Chand M; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicinegrid.471390.8, New Haven, Connecticut, USA., Singh P; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicinegrid.471390.8, New Haven, Connecticut, USA., Lamba P; Department of Medicine (Division of Infectious Diseases), Stony Brook University Renaissance School of Medicine, Stony Brook, New York, USA.; Department of Microbiology and Immunology, Stony Brook University Renaissance School of Medicine, Stony Brook, New York, USA., Gaur G; L2 Diagnostics, LLC, New Haven, Connecticut, USA., Pal AC; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicinegrid.471390.8, New Haven, Connecticut, USA., Mootien S; L2 Diagnostics, LLC, New Haven, Connecticut, USA., Marcos LA; Department of Medicine (Division of Infectious Diseases), Stony Brook University Renaissance School of Medicine, Stony Brook, New York, USA.; Department of Microbiology and Immunology, Stony Brook University Renaissance School of Medicine, Stony Brook, New York, USA., Ben Mamoun C; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicinegrid.471390.8, New Haven, Connecticut, USA., Ledizet M; L2 Diagnostics, LLC, New Haven, Connecticut, USA.

Publikováno v: Journal of clinical microbiology [J Clin Microbiol] 2022 Sep 21; Vol. 60 (9), pp. e0092522. Date of Electronic Publication: 2022 Aug 30.