Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Pakit Kumboonma"'
Autor:
La-or Somsakeesit, Anupong Joompang, Santi Phosr, Pattaravadee Srikoon, Pakit Kumboonma, Thanaset Senawong, Chanokbhorn Phaosiri
Publikováno v:
Songklanakarin Journal of Science and Technology (SJST), Vol 44, Iss 6, Pp 1481-1488 (2022)
Piperine (1) was obtained from the seeds of Piper nigrum L. It could act as a pan-histone deacetylase (HDAC) inhibitor. This lead compound was structurally modified to six derivatives that exhibited improved HDAC inhibitory activity. Based on the p
Externí odkaz:
https://doaj.org/article/fb0291b4a4874c05b059ffa285edfd17
Autor:
Narissara Namwan, Gulsiri Senawong, Chanokbhorn Phaosiri, Pakit Kumboonma, La-or Somsakeesit, Arunta Samankul, Chadaporn Leerat, Thanaset Senawong
Publikováno v:
Molecules, Vol 27, Iss 13, p 4014 (2022)
Previous research reported that the curcumin derivative (CU17) inhibited several cancer cell growths in vitro. However, its anticancer potential against human lung cancer cells (A549 cell lines) has not yet been evaluated. The purpose of this researc
Externí odkaz:
https://doaj.org/article/1031ee61ca0f4df8ac59e81e0e31ceb3
Autor:
Chanokbhorn Phaosiri, Chavi Yenjai, Thanaset Senawong, Gulsiri Senawong, Somprasong Saenglee, La-or Somsakeesit, Pakit Kumboonma
Publikováno v:
Molecules, Vol 27, Iss 10, p 3332 (2022)
Twenty newly synthesized derivatives of [6]-shogaol (4) were tested for inhibitory activity against histone deacetylases. All derivatives showed moderate to good histone deacetylase inhibition at 100 µM with a slightly lower potency than the lead co
Externí odkaz:
https://doaj.org/article/350cf8cd211542be831d2503c15d52bf
Publikováno v:
Songklanakarin Journal of Science and Technology (SJST), Vol 38, Iss 4, Pp 399-406 (2016)
The natural products, capsaicin and dihydrocapsaicin, were modified at double-bond and phenolic moieties to provide twelve capsaicin and dihydrocapsaicin derivatives. The natural products and synthesized compounds were evaluated as histone deacetyl
Externí odkaz:
https://doaj.org/article/5367998dd7d442e9a928a28f2c60c907
Autor:
Panom Winyayong, Passakorn Teerapongpisan, Thanakorn Mongantha, Patcharapol Siliwelawan, Chama Thamjamnein, Pakit Kumboonma, Surat Laphookhieo, Phunrawie Promnart
Publikováno v:
Trends in Sciences; Nov2024, Vol. 21 Issue 11, p1-12, 12p
Autor:
Virayu Suthiphasilp, Narawadee Rujanapun, Pakit Kumboonma, Boonyanoot Chaiyosang, Sarawut Tontapha, Tharakorn Maneerat, Brian O Patrick, Raymond J Andersen, Thidarat Duangyod, Rawiwan Charoensup, Surat Laphookhieo
Publikováno v:
ACS Omega. 7:24511-24521
Autor:
Passakorn Teerapongpisan, Virayu Suthiphasilp, Pakit Kumboonma, Tharakorn Maneerat, Thidarat Duangyod, Rawiwan Charoensup, Raymond J. Andersen, Surat Laphookhieo
Publikováno v:
Phytochemistry. 212:113717
Publikováno v:
Organic Communications. :133-143
Autor:
Thanaset Senawong, Somprasong Saenglee, La-or Somsakeesit, Gulsiri Senawong, Pakit Kumboonma, Chanokbhorn Phaosiri, Chavi Yenjai
Publikováno v:
Medicinal Chemistry Research. 28:1773-1782
The aims of this study were to explore histone deacetylase inhibitory and antioxidant activities of curcuminoids as well as derivatives of curcumin. Curcumin (6), demethoxycurcumin (7), dihydrocurcumin (8), bisdemethoxycurcumin (9), and hydroxycurcum
Publikováno v:
Medicinal Chemistry Research. 27:2004-2015
Two new compounds, melanorrone (1) and melanorric acid (2), as well as 19 known compounds were isolated and identified from the twigs of Melanorrhoea usitata. Their structures were determined by spectroscopic methods (IR, 1H-NMR, 13C-NMR, 2D-NMR, MS,