Zobrazeno 1 - 10
of 2 320
pro vyhledávání: '"Pak H"'
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 2, Pp 440-449 (2012)
Oxidative stress and glucose affect the expression of various genes that contribute to both reactive oxygen species generation and antioxidant systems. However, systemic alteration of oxidative stress-related gene expression in normal brains and in b
Externí odkaz:
https://doaj.org/article/bfbece36fab94949b6f6ad68fc6647e4
Publikováno v:
Neurobiology of Disease, Vol 42, Iss 3, Pp 341-348 (2011)
Nicotinamide adenine dinucleotide phosphate oxidase (NOX) is widely expressed in brain tissue including neurons, glia, and endothelia in neurovascular units. It is a major source of oxidants in the post-ischemic brain and significantly contributes to
Externí odkaz:
https://doaj.org/article/a8f500e44a15414d874c4d0e76389c13
Publikováno v:
MATEC Web of Conferences, Vol 170, p 01073 (2018)
The article examines the financial stability of municipalities in conjunction with financial and budgetary security. The analytical base is provided by the information of the Federal State Statistics Service, the section Municipal Statistics, the dat
Externí odkaz:
https://doaj.org/article/b0bcd5588a894286a9bd14256cca885a
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 2, Pp 491-499 (2005)
The serine–threonine kinase Akt is a cell survival signaling pathway that inactivates the proapoptotic BCL-2 family protein Bad and promotes cell survival in cerebral ischemia. Involvement of the Akt/Bad signaling pathway after spinal cord injury (
Externí odkaz:
https://doaj.org/article/91c1bbd8b89b4451b83957bd1d6beafd
Publikováno v:
Neurobiology of Disease, Vol 15, Iss 2, Pp 229-239 (2004)
Oxidative damage to the endoplasmic reticulum (ER) could be involved in ischemic neuronal cell death because this organelle is susceptible to reactive oxygen species. Using wild-type mice and copper/zinc-superoxide dismutase (SOD1) transgenic mice, w
Externí odkaz:
https://doaj.org/article/45d74c1ea5874790a377b1c13a9530b0
Autor:
Carolina M. Maier, Guo Hua Sun, Danye Cheng, Midori A. Yenari, Pak H. Chan, Gary K. Steinberg
Publikováno v:
Neurobiology of Disease, Vol 11, Iss 1, Pp 28-42 (2002)
Following a transient ischemic insult there is a marked increase in free radical (FR) production within the first 10–15 min of reperfusion and again at the peak of the inflammatory process. Hypothermia decreases lipid peroxidation following global
Externí odkaz:
https://doaj.org/article/1ab8d3dca5364023a5b47087d9fd59d1
Publikováno v:
Neurobiology of Disease, Vol 9, Iss 3, Pp 294-304 (2002)
The serine-threonine kinase, Akt, is involved in the survival signaling pathways in many cell systems. The present study examined phosphorylation of Akt at serine-473 and DNA fragmentation after traumatic brain injury (TBI) in mice. Immunohistochemis
Externí odkaz:
https://doaj.org/article/09a71b6a3b984bde8036f9a23b7518f5
Autor:
Yu-Yo Sun, Yury M Morozov, Dianer Yang, Yikun Li, R Scott Dunn, Pasko Rakic, Pak H Chan, Koji Abe, Diana M Lindquist, Chia-Yi Kuan
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98807 (2014)
Edaravone, a potent antioxidant, may improve thrombolytic therapy because it benefits ischemic stroke patients on its own and mitigates adverse effects of tissue plasminogen activator (tPA) in preclinical models. However, whether the combined tPA-eda
Externí odkaz:
https://doaj.org/article/46b6060a8b7243149c112cf5d943802f
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 3, Pp 380-390 (2001)
The DNA repair enzyme, apurinic/apyrimidinic endonuclease (or redox effector factor-1, APE/Ref-1), is involved in base excision repair of apurinic/apyrimidinic sites after oxidative DNA damage. We investigated the expression of APE/Ref-1 and its rela
Externí odkaz:
https://doaj.org/article/81d286a5e86647ebbb47195e9a3f0ea8