Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Paivi Burke"'
Autor:
Vala Hamidi, Paivi Burke, Leslie Carter, Daniel G. Ines, Jeremy Pettus, Erin R. Giovannetti, Schafer Boeder, Adrienne Armstrong
Publikováno v:
Diabetes. 70
Individuals with T1D have an ineffective glucagon response to low glucose levels which predisposes them to episodes of hypoglycemia. SGLT-2 inhibitors (SGLT2i) do not increase and may even reduce hypoglycemia in clinical trials, yet the mechanism is
Autor:
Jeremy Pettus, Erin R. Giovannetti, Leslie Carter, Daniel G. Ines, Debra Armstrong, Schafer Boeder, Paivi Burke
Publikováno v:
Diabetes. 69
Background: Diabetic ketoacidosis is a common and life-threatening complication of T1D. Glucagon stimulates ketogenesis via peripheral lipolysis and hepatic β-oxidation of free fatty acids (FFA). Blocking glucagon action may decrease ketone formatio
Autor:
Theodore P. Ciaraldi, Eric Chen Quin Lam, Debra Armstrong, Helle Linnebjerg, Melvin J. Prince, Scott J. Jacober, Parag Garhyan, Niels Porksen, Robert R. Henry, Paivi Burke, Jeremy Pettus, Vikram Sinha, Namrata Bose, S. L. Choi, Sunder Mudaliar, Mary Pat Knadler
Publikováno v:
Diabetes Care. 37:2609-2615
OBJECTIVE We evaluated the endogenous glucose production (EGP) and glucose disposal rate (GDR) over a range of doses of basal insulin peglispro (BIL) and insulin glargine in healthy subjects. RESEARCH DESIGN AND METHODS This was a single-center, rand
Autor:
Theodore P. Ciaraldi, Monica Ligueros-Saylan, Paivi Burke, Debra Armstrong, Robert R. Henry, Sunder Mudaliar
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 98:3446-3453
Pasireotide (SOM230) is a somatostatin analog with affinity for somatostatin receptor subtypes sst₁₋₃ and sst₅. Clinical trials have demonstrated the efficacy of pasireotide in treating Cushing's disease and acromegaly but have also shown adv
Autor:
Parag Garhyan, Niels Porksen, Paivi Burke, S. L. Choi, Mary Pat Knadler, Robert R. Henry, Helle Linnebjerg, Vikram Sinha, Debra Armstrong, Eric Chen Quin Lam, Theodore P. Ciaraldi, Scott J. Jacober, Jeremy Pettus, Sunder Mudaliar, N. Bose, Melvin J. Prince
Publikováno v:
Diabetes, obesitymetabolism. 18
Aims Basal insulin peglispro (BIL), a novel PEGylated basal insulin with a large hydrodynamic size, has a delayed absorption and reduced clearance that prolongs the duration of action. The current study compared the effects of BIL and insulin glargin
Autor:
Paivi Burke, Robert R. Henry, E. Chao, Vanita R. Aroda, Sunita Baxi, A. R. Chang, Daniel T. O'Connor, Sunder Mudaliar, K. A. Griver
Publikováno v:
Diabetes, Obesity and Metabolism. 12:133-138
Objective: To evaluate the effects of intensive insulin therapy alone or with added pioglitazone on renal salt/water balance and body fluid compartment shifts in type 2 diabetes. Methods: A total of 25 insulin-treated, obese patients with type 2 diab
Autor:
Sunder Mudaliar, Paivi Burke, Theodore P. Ciaraldi, Paul Clopton, R. Jeffrey Chang, Robert R. Henry, Susan A. Phillips, Vanita R. Aroda
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 94:469-476
Context: Polycystic ovary syndrome (PCOS) is characterized by insulin resistance, compensatory hyperinsulinemia, increased prevalence of impaired glucose tolerance, and increased ovarian androgen biosynthesis. Objective: The aim of the study was to e
Autor:
Paivi Burke, Sunder Mudaliar, Vanita R. Aroda, Robert R. Henry, A. R. Chang, Pankil Shah, Michael P. Andre
Publikováno v:
Diabetes, obesitymetabolism. 13(6)
Aim: To evaluate the effects of intensive insulin therapy alone and with added pioglitazone on body weight, fat distribution, lean body mass (LBM) and liver fat in type 2 diabetic patients. Methods: Twenty-five insulin-treated, obese patients with ty