Solution Structure and Conformational Flexibility of a Polyketide Synthase Module.

Autor: Klaus M; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue Strasse 15, Frankfurt am Main 60438, Germany., Rossini E; Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Max-von-Laue Strasse 3, Frankfurt am Main 60438, Germany., Linden A; Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Goettingen 37077, Germany.; Institute for Clinical Chemistry, University Medical Center Göttingen, Robert Koch Strasse 40, Goettingen 37075, Germany., Paithankar KS; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue Strasse 15, Frankfurt am Main 60438, Germany., Zeug M; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue Strasse 15, Frankfurt am Main 60438, Germany., Ignatova Z; Institute for Biochemistry and Molecular Biology, University of Hamburg, Notkestrasse 85, Hamburg 22607, Germany., Urlaub H; Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, Goettingen 37077, Germany.; Institute for Clinical Chemistry, University Medical Center Göttingen, Robert Koch Strasse 40, Goettingen 37075, Germany., Khosla C; Department of Chemistry, Stanford ChEM-H, Department of Chemical Engineering Stanford University, Stanford, California 94305, United States., Köfinger J; Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Max-von-Laue Strasse 3, Frankfurt am Main 60438, Germany., Hummer G; Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Max-von-Laue Strasse 3, Frankfurt am Main 60438, Germany.; Institute of Biophysics, Goethe University Frankfurt, Max-von-Laue Strasse 1, Frankfurt am Main 60438, Germany., Grininger M; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue Strasse 15, Frankfurt am Main 60438, Germany.

Publikováno v: JACS Au [JACS Au] 2021 Oct 18; Vol. 1 (12), pp. 2162-2171. Date of Electronic Publication: 2021 Oct 18 (Print Publication: 2021).

The resolution revolution in cryoEM requires high-quality sample preparation: a rapid pipeline to a high-resolution map of yeast fatty acid synthase.

Autor: Joppe M; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., D'Imprima E; Department of Structural Biology, Max Planck Institute of Biophysics, Max-von-Laue Strasse 3, 60438 Frankfurt am Main, Germany., Salustros N; Department of Structural Biology, Max Planck Institute of Biophysics, Max-von-Laue Strasse 3, 60438 Frankfurt am Main, Germany., Paithankar KS; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., Vonck J; Department of Structural Biology, Max Planck Institute of Biophysics, Max-von-Laue Strasse 3, 60438 Frankfurt am Main, Germany., Grininger M; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., Kühlbrandt W; Department of Structural Biology, Max Planck Institute of Biophysics, Max-von-Laue Strasse 3, 60438 Frankfurt am Main, Germany.

Publikováno v: IUCrJ [IUCrJ] 2020 Jan 25; Vol. 7 (Pt 2), pp. 220-227. Date of Electronic Publication: 2020 Jan 25 (Print Publication: 2020).

Structure of the archaeal chemotaxis protein CheY in a domain-swapped dimeric conformation.

Autor: Paithankar KS; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., Enderle M; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., Wirthensohn DC; Department of Membrane Biochemistry, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany., Miller A; Department of Membrane Biochemistry, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany., Schlesner M; Department of Membrane Biochemistry, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany., Pfeiffer F; Computational Biology Group, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany., Rittner A; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., Grininger M; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., Oesterhelt D; Department of Membrane Biochemistry, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany.

Publikováno v: Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2019 Sep 01; Vol. 75 (Pt 9), pp. 576-585. Date of Electronic Publication: 2019 Aug 30.

Characterization of the Polyspecific Transferase of Murine Type I Fatty Acid Synthase (FAS) and Implications for Polyketide Synthase (PKS) Engineering.

Autor: Rittner A; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Cluster of Excellence for Macromolecular Complexes , Goethe University Frankfurt , Max-von-Laue-Str. 15 , 60438 Frankfurt am Main , Germany., Paithankar KS; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Cluster of Excellence for Macromolecular Complexes , Goethe University Frankfurt , Max-von-Laue-Str. 15 , 60438 Frankfurt am Main , Germany., Huu KV; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Cluster of Excellence for Macromolecular Complexes , Goethe University Frankfurt , Max-von-Laue-Str. 15 , 60438 Frankfurt am Main , Germany., Grininger M; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Cluster of Excellence for Macromolecular Complexes , Goethe University Frankfurt , Max-von-Laue-Str. 15 , 60438 Frankfurt am Main , Germany.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2018 Mar 16; Vol. 13 (3), pp. 723-732. Date of Electronic Publication: 2018 Feb 01.

Crystallization and X-ray diffraction studies of a complete bacterial fatty-acid synthase type I.

Autor: Enderle M; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., McCarthy A; EMBL Grenoble, 71 Avenue des Martyrs, 38042 Grenoble CEDEX 9, France., Paithankar KS; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany., Grininger M; Institute of Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Strasse 15, 60438 Frankfurt am Main, Germany.

Publikováno v: Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2015 Nov; Vol. 71 (Pt 11), pp. 1401-7. Date of Electronic Publication: 2015 Oct 23.