Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Paishiun N. Hsieh"'
Autor:
Paishiun N. Hsieh, Guangjin Zhou, Yiyuan Yuan, Rongli Zhang, Domenick A. Prosdocimo, Panjamaporn Sangwung, Anna H. Borton, Evgenii Boriushkin, Anne Hamik, Hisashi Fujioka, Ciaran E. Fealy, John P. Kirwan, Maureen Peters, Yuan Lu, Xudong Liao, Diana Ramírez-Bergeron, Zhaoyang Feng, Mukesh K. Jain
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
KLF family transcription factors (KLFs) regulate many cellular processes, including proliferation, survival and stress responses. Here, the authors position KLFs as important regulators of autophagy and lifespan in C. elegans, a role that may extend
Externí odkaz:
https://doaj.org/article/f6fefca5fe574b6cb4028da608dba560
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
The role of inflammation in vascular disease is well recognized, involving dysregulation of both circulating immune cells as well as the cells of the vessel wall itself. Unrestrained vascular inflammation leads to pathological remodeling that eventua
Externí odkaz:
https://doaj.org/article/65af82d82e684671adc428c31ea11df4
Autor:
Saumendra N. Sarkar, Robert L. Ferris, Pawel Kalinski, Ravikumar Muthuswamy, Paishiun N. Hsieh, Adriana Forero, Yvonne K. Mburu, Jianzhong Zhu, Naoki Umemura
PDF file - 520K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f9a4d05fdf165d20addd4be2f824fa
https://doi.org/10.1158/0008-5472.22393731.v1
https://doi.org/10.1158/0008-5472.22393731.v1
Autor:
Keiki Sugi, Paishiun N Hsieh, Olga Ilkayeva, Shamanthika Shelkay, Bridget Moroney, Palvir Baadh, Browning Haynes, Megan Pophal, Liyan Fan, Christopher B Newgard, Domenick A Prosdocimo, Mukesh K Jain
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192376 (2018)
Cardiac metabolism is highly adaptive in response to changes in substrate availability, as occur during fasting. This metabolic flexibility is essential to the maintenance of contractile function and is under the control of a group of select transcri
Externí odkaz:
https://doaj.org/article/60ff0ea696484aa189649c00d245fea6
Publikováno v:
Endocrine Reviews. 40:137-152
Nutrient handling by higher organisms is a complex process that is regulated at the transcriptional level. Studies over the past 15 years have highlighted the critical importance of a family of transcriptional regulators termed the Krüppel-like fact
Autor:
Charles F. McTiernan, Christine S. Moravec, Samir Saba, Vladimir Shusterman, Kenneth Bedi, Paishiun N. Hsieh, Kenneth B. Margulies, Bonnie Lemster
Publikováno v:
Circ Arrhythm Electrophysiol
Background: Ventricular tachyarrhythmias and sudden cardiac death show a circadian pattern of occurrence in patients with heart failure. In the rodent ventricle, a significant portion of genes, including some ion channels, shows a circadian pattern o
Publikováno v:
Cellular and Molecular Life Sciences
Over the course of a 24-h day, demand on the heart rises and falls with the sleep/wake cycles of the organism. Cardiac metabolism oscillates appropriately, with the relative contributions of major energy sources changing in a circadian fashion. The c
Autor:
Mukesh K. Jain, Paishiun N. Hsieh, Jonathan S. Stamler, Steven P. Gygi, Liwen Wang, Suhib Jamal, Puneet Seth, Jeff Coller
Publikováno v:
Cell. 176(5)
Summary Bioactive molecules can pass between microbiota and host to influence host cellular functions. However, general principles of interspecies communication have not been discovered. We show here in C. elegans that nitric oxide derived from resid
Publikováno v:
Trends in cellmolecular biology. 12
The mammalian Krüppel-like factors (KLFs) are a family of zinc-finger containing transcription factors with diverse patterns of expression and a wide array of cellular functions. While their roles in mammalian physiology are well known, there is a g
Autor:
Browning Haynes, Domenick A. Prosdocimo, Megan Pophal, Mukesh K. Jain, Shamanthika Shelkay, Palvir K. Baadh, Liyan Fan, Olga Ilkayeva, Bridget Moroney, Paishiun N. Hsieh, Christopher B. Newgard, Keiki Sugi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 2, p e0192376 (2018)
PLoS ONE, Vol 13, Iss 2, p e0192376 (2018)
Cardiac metabolism is highly adaptive in response to changes in substrate availability, as occur during fasting. This metabolic flexibility is essential to the maintenance of contractile function and is under the control of a group of select transcri