Th17 cells in systemic lupus erythematosus share functional features with Th17 cells from normal bone marrow and peripheral tissues

Autor: Henriques, A, Inês, L, Pais, ML, Pereira da Silva, JA, Paiva, AA

This study was designed to investigate the functional heterogeneity of human Th17 and how their plasticity shapes the nature of immune cell responses to inflammation and autoimmune diseases, such as systemic lupus erythematosus (SLE). We evaluated fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1504::82fbab152a48a2204bf7ede5215d270f
https://hdl.handle.net/10400.4/1128

Perioperative tumor cell dissemination in patients with primary or metastatic colorectal cancer

Autor: Tralhão, JG, Hoti, E, Serôdio, M, Laranjeiro, P, Paiva, A, Abrantes, AM, Pais, ML, Botelho, MF, Castro e Sousa, F

INTRODUCTION: Although there is general correlation between the TNM stage of colorectal cancer (CRC) and its prognosis, there is often significant variability of tumor behaviour and individual patient outcome, which is unaccounted for by pathologic f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1504::92ed54bc3270515372ddc0e2e119d876
https://hdl.handle.net/10400.4/547

Increased functional connectivity between brain regions involved in social cognition, emotion and affective-value in psychedelic states induced by N,N-Dimethyltryptamine (DMT).

Autor: Soares C; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), Institute of Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, Coimbra, Portugal.; Faculty of Medicine (FMUC), University of Coimbra, Coimbra, Portugal., Lima G; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), Institute of Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, Coimbra, Portugal.; Faculty of Medicine (FMUC), University of Coimbra, Coimbra, Portugal., Pais ML; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), Institute of Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, Coimbra, Portugal., Teixeira M; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), Institute of Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, Coimbra, Portugal., Cabral C; Clinic Academic Center of Coimbra (CACC), Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Coimbra, Portugal.; Department of Life Sciences, Centre for Functional Ecology, University of Coimbra, Coimbra, Portugal., Castelo-Branco M; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), Institute of Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, Coimbra, Portugal.; Faculty of Medicine (FMUC), University of Coimbra, Coimbra, Portugal.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2024 Oct 30; Vol. 15, pp. 1454628. Date of Electronic Publication: 2024 Oct 30 (Print Publication: 2024).

Rapid effects of tryptamine psychedelics on perceptual distortions and early visual cortical population receptive fields.

Autor: Pais ML; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), University of Coimbra, Portugal; Institute of Nuclear Sciences Applied to Health (ICNAS), Portugal., Teixeira M; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), University of Coimbra, Portugal; Institute of Nuclear Sciences Applied to Health (ICNAS), Portugal., Soares C; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), University of Coimbra, Portugal; Institute of Nuclear Sciences Applied to Health (ICNAS), Portugal., Lima G; Institute of Nuclear Sciences Applied to Health (ICNAS), Portugal; University of Maastricht, the Netherlands; Faculty of Medicine (FMUC), University of Coimbra, Portugal., Rijo P; CBIOS-Universidade Lusófona's Research Center for Biosciences & Health Technologies, Portugal; iMed.ULisboa, Faculty of Pharmacy, University of Lisbon, Portugal., Cabral C; Coimbra Institute for Clinical and Biomedical Research (iCBR), Clinic Academic Center of Coimbra (CACC), University of Coimbra, FMUC, Portugal; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, Portugal; Centre for Functional Ecology, Department of Life Sciences, University of Coimbra, Portugal., Castelo-Branco M; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), University of Coimbra, Portugal; Institute of Nuclear Sciences Applied to Health (ICNAS), Portugal; University of Maastricht, the Netherlands; Faculty of Medicine (FMUC), University of Coimbra, Portugal. Electronic address: mcbranco@fmed.uc.pt.

Publikováno v: NeuroImage [Neuroimage] 2024 Aug 15; Vol. 297, pp. 120718. Date of Electronic Publication: 2024 Jul 02.

Portuguese observational cross-sectional clinical imaging study protocol to investigate central dopaminergic mechanisms of successful weight loss through bariatric surgery.

Autor: Pais ML; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), University of Coimbra, Coimbra, Portugal.; Institute for Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, Coimbra, Portugal.; Faculty of Science and Technology, University of Coimbra, Coimbra, Portugal., Crisóstomo J; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), University of Coimbra, Coimbra, Portugal.; Champalimaud Research, Champalimaud Foundation, Lisbon, Portugal., Abrunhosa A; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), University of Coimbra, Coimbra, Portugal.; Institute for Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, Coimbra, Portugal., Castelo-Branco M; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), University of Coimbra, Coimbra, Portugal mcbranco@fmed.uc.pt.; Institute for Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, Coimbra, Portugal.

Publikováno v: BMJ open [BMJ Open] 2024 Apr 02; Vol. 14 (4), pp. e080702. Date of Electronic Publication: 2024 Apr 02.