Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Paired immunoglobulin-like receptor B"'
Autor:
Xiaoyu Meng, Danpei Li, Ranran Kan, Yuxi Xiang, Limeng Pan, Yaming Guo, Peng Yu, Peiqiong Luo, Huajie Zou, Li Huang, Yurong Zhu, Beibei Mao, Yi He, Lei Xie, Jialu Xu, Xiaoyan Liu, Wenjun Li, Yong Chen, Suiqiang Zhu, Yan Yang, Xuefeng Yu
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Background Type 2 diabetes mellitus (T2D) is associated with an increased risk of cognitive dysfunction. Angiopoietin-like protein 8 (ANGPTL8) is an important regulator in T2D, but the role of ANGPTL8 in diabetes-associated cognitive dysfunc
Externí odkaz:
https://doaj.org/article/0433053d232846b998d7b57d5f0301dd
Autor:
Yuki Kawaguchi, Junpei Matsubayashi, Yutaka Kawakami, Ryohei Nishida, Yuji Kurihara, Kohtaro Takei
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-13 (2022)
Abstract Background Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide but has no effective treatment. Amyloid beta (Aβ) protein, a primary risk factor for AD, accumulates and aggregates in the brain of patients with A
Externí odkaz:
https://doaj.org/article/48f01a0cce6b4ca8bd522ad02c01bcd8
Akademický článek
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Publikováno v:
Di-san junyi daxue xuebao, Vol 42, Iss 1, Pp 39-44 (2020)
Objective To investigate the pro-inflammatory effects and mechanisms of angiopoietin-like protein 2 (Angptl2) in the eyes. Methods SD rats (8 weeks old) were given a single intravitreal injection of 0.2 mg LPS or PBS to establish intraocular inflamma
Externí odkaz:
https://doaj.org/article/d448a2b83a394ff1bf4c9fa9ec31d273
Akademický článek
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Akademický článek
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Publikováno v:
Neural Regeneration Research, Vol 10, Iss 8, Pp 1338-1342 (2015)
Regenerative capacity is weak after central nervous system injury because of the absence of an enhancing microenvironment and presence of an inhibitory microenvironment for neuronal and axonal repair. In addition to the Nogo receptor (NgR), the paire
Externí odkaz:
https://doaj.org/article/bbe130b8a27a4a4a99b25025fab116dc
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 7, Pp 1139-1146 (2015)
Paired immunoglobulin-like receptor B (PirB) is a functional receptor of myelin-associated inhibitors for axonal regeneration and synaptic plasticity in the central nervous system, and thus suppresses nerve regeneration. The regulatory effect of PirB
Externí odkaz:
https://doaj.org/article/aeaee187da924f6daa136c98f2d383c2
Autor:
Kasper Hoebe, Shrinivas Bishu, John Y. Kao, Varsha Ganesan, Ankit Sharma, Yanfen Yang, Chang Zeng, Rodney D. Newberry, Sahiti Marella, Simon P. Hogan, Philip D. King, Ariel Munitz, Jazib Uddin, Taeko K. Noah, Lee A. Denson, Andrew R. Patterson, Simone Vanoni, Lisa Waggoner, Senad Divanovic, Paul S. Foster, Michael J. Rosen, S. M. S. Tomar
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1479-1502 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1479-1502 (2021)
Background & Aims CD4+ T cells are regulated by activating and inhibitory cues, and dysregulation of these proper regulatory inputs predisposes these cells to aberrant inflammation and exacerbation of disease. We investigated the role of the inhibito
Autor:
Zhi Nie, Wenjing Cheng, Baiyang Liu, Yongbin Chen, Cuifeng Xia, Cui-Ping Yang, Jun Pu, Dating Cheng
Publikováno v:
Aging (Albany NY)
Neural stem cells play pivotal roles during prenatal development and throughout life. Here, we report that Paired immunoglobulin-like receptor B (PirB) functions as a suppressor during brain neurogenesis in the adult mouse. PirB expression increased