Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Paired Box Transcription Factors/genetics/metabolism"'
Autor:
Marc Y. Donath, Anne Wojtusciszyn, Bernhard O. Boehm, Kai Hui Hu He, Kathrin Maedler, Piero Marchetti, Nadine S. Sauter, Roberto Lupi, Benoit R. Gauthier, Thierry Brun
Publikováno v:
BASE-Bielefeld Academic Search Engine
Human molecular genetics, Vol. 17, No 4 (2008) pp. 478-89
Human molecular genetics, Vol. 17, No 4 (2008) pp. 478-89
We previously demonstrated that the transcription factor Pax4 is important for beta-cell replication and survival in rat islets. Herein, we investigate Pax4 expression in islets of non-diabetic and diabetic donors, its regulation by mitogens, glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c9b2c00f8a68d3a9851326c5e5a334
http://doc.rero.ch/record/299485/files/ddm325.pdf
http://doc.rero.ch/record/299485/files/ddm325.pdf
Autor:
Caroline Poisson, Mounia Heddad Masson, Jacques Philippe, Yvan Gosmain, Audrey Guérardel, Claire Cheyssac
Publikováno v:
Endocrinology, Vol. 153, No 9 (2012) pp. 4204-15
The Pax6 transcription factor is crucial for pancreatic α-cells. Indeed, Pax6-deficient mouse models are characterized by markedly altered α-cell differentiation. Our objective was to investigate the role of Pax6 in glucagon secretion process. We u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4e08a66a1b2e4c08788194ee66248e
https://doi.org/10.1210/en.2012-1425
https://doi.org/10.1210/en.2012-1425
Autor:
Rocio Garcia-Carbonero, Anabel Rojas, Raphael P. H. Meier, Benoit R. Gauthier, Lourdes Gomez-Izquierdo, Carmen M. Jimenez Moreno, Nadia Cobo-Vuilleumier, Petra I. Lorenzo, Thierry Berney, Irene Delgado
Publikováno v:
Histochemistry and Cell Biology
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
Histochemistry and Cell Biology, Vol. 136, No 5 (2011) pp. 595-607
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
Histochemistry and Cell Biology, Vol. 136, No 5 (2011) pp. 595-607
This article is distributed under the terms of the Creative Commons Attribution Noncommercial License.-- et al.
The paired box transcription factor Pax8 is critical for development of the eye, thyroid gland as well as the urinary and reproductiv
The paired box transcription factor Pax8 is critical for development of the eye, thyroid gland as well as the urinary and reproductiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8f7024d3c6fd0ddd5422bd85332df1
https://doi.org/10.1007/s00418-011-0866-3
https://doi.org/10.1007/s00418-011-0866-3
Autor:
Asllan Gjinovci, Carmen M. Jimenez Moreno, Claes B. Wollheim, Kai Hui Hu He, Deborah Aeberhard, Fabrizio Thorel, Marion Cornu, Benoit R. Gauthier, Petra I. Lorenzo, Jorge Vallejo Ortega, Pedro Luis Herrera, Thierry Brun, Bernard Thorens, Paolo Meda
Publikováno v:
Diabetes
Diabetes, Vol. 60, No 6 (2011) pp. 1705-15
Diabetes; Vol 60
Diabetes, vol. 60, no. 6, pp. 1705-1715
Digital.CSIC. Repositorio Institucional del CSIC
instname
Diabetes, Vol. 60, No 6 (2011) pp. 1705-15
Diabetes; Vol 60
Diabetes, vol. 60, no. 6, pp. 1705-1715
Digital.CSIC. Repositorio Institucional del CSIC
instname
et al.
[Objective]: To establish the role of the transcription factor Pax4 in pancreatic islet expansion and survival in response to physiological stress and its impact on glucose metabolism, we generated transgenic mice conditionally and select
[Objective]: To establish the role of the transcription factor Pax4 in pancreatic islet expansion and survival in response to physiological stress and its impact on glucose metabolism, we generated transgenic mice conditionally and select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43996fb6545ff2cf025baf9d4ab3104
https://doi.org/10.2337/db10-1102
https://doi.org/10.2337/db10-1102
Publikováno v:
Diabetes, Obesity and Metabolism, Vol. 13 Suppl 1 (2011) pp. 31-8
Diabetes obesity & metabolism
Diabetes obesity & metabolism
The glucagon gene is expressed in α-cells of the pancreas, L cells of the intestine and the hypothalamus. The determinants of the α-cell-specific expression of the glucagon gene are not fully characterized, although Arx, Pax6 and Foxa2 are critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9662250ca3fa0f22320257e53babf73d
https://archive-ouverte.unige.ch/unige:25626
https://archive-ouverte.unige.ch/unige:25626