Výsledky vyhledávání - "Paired Box Transcription Factors/*physiology"

Pax6 Regulates the Proglucagon Processing Enzyme PC2 and Its Chaperone 7B2▿ †

Autor: Jacques Philippe, Liora S. Katz, Yvan Gosmain, Eric Marthinet

Publikováno v: Molecular and Cellular Biology, Vol. 29, No 8 (2009) pp. 2322-2334

Pax6 is important in the development of the pancreas and was previously shown to regulate pancreatic endocrine differentiation, as well as the insulin, glucagon, and somatostatin genes. Prohormone convertase 2 (PC2) is the main processing enzyme in p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c5236d1e1c8118fb84053c76a0e1dc
https://europepmc.org/articles/PMC2663301/

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Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets

Autor: Domenico Bosco, Reto M. Baertschiger, Yoichiro Iwakura, Jose Oberholzer, Benoit R. Gauthier, Claes B. Wollheim, Marc Y. Donath, Helga Ellingsgaard, Nadine S. Sauter, Desiree M. Schumann, Kathrin Maedler

Publikováno v: Diabetes, Vol. 55, No 10 (2006) pp. 2713-22

High glucose concentrations have a dual effect on beta-cell turnover, inducing proliferation in the short-term and apoptosis in the long-term. Hyperglycemia leads to beta-cell production of interleuking (IL)-1beta in human pancreatic islets. Fas, a d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af167f76184b62e33f6726df0f74dfa
https://archive-ouverte.unige.ch/unige:34523

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